Test Bank For Psychopharmacology: Drugs, the Brain and Behavior 4th Edition By Meyer,ISBN; 9781605359878 All Chapters Fully Covered,Complete Guide A+.

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, Chapter 1: Principles of Pharmacology

Multiple Choice

1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action

2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action

3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action

4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action




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,5. The administration $hnof $hnoxytocin $hnhas $hnbeen $hnproposed $hnas $hna $hntreatment $hnfor
$hnautism.

a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: $hnc
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

6. Which $hnfactor $hndoes $hnnot $hnaffect $hnthe $hnpharmacokinetics $hnof $hna $hndrug?
a. Route $hnof $hnadministration
b. Lipid $hnsolubility
c. Depot $hnbinding
d. Drug $hnaction
Answer: $hnd
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

7. First-pass $hnmetabolism $hnoccurs $hnwhen $hndrugs $hnare $hntaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: $hna
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

8. The $hnarea $hnpostrema $hnis $hnone $hnarea $hnin $hnthe $hnbrain $hnwhere $hnthe is $hnnot $hncomplete.
a. cerebrospinal $hnfluid
b. blood–brain $hnbarrier
c. choroid $hnplexus
d. phospholipid $hnmembrane
Answer: $hnb
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

9. First-pass $hnmetabolism $hnoccurs $hnwith $hnorally $hnadministered $hndrugs $hnbecause
a. their $hnabsorption $hnis $hnslowed $hnby $hnfood.
b. drugs $hnabsorbed $hninto $hnthe $hnbloodstream $hnfrom $hnthe $hnstomach $hngo $hnto $hnthe $hnliver
$hnon $hnthe $hnway $hnto $hngeneral $hncirculation.

c. drugs $hnmust $hnfirst $hnsurvive $hnthe $hnacidic $hnenvironment $hnof $hnthe $hnstomach.
d. salivary $hnenzymes $hnin $hnthe $hnmouth $hnbegin $hnthe $hnprocess $hnof $hnmetabolism.
Answer: $hnb
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

10. Toxic $hnsubstances $hnin $hnthe $hnblood $hntrigger $hna $hnvomiting $hnresponse $hnby $hnactivating $hnthe
a. blood–brain $hnbarrier.
b. choroid $hnplexus.
c. area $hnpostrema.
d. median $hneminence.


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, Answer: $hnc
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

11. Drugs $hnadministered $hn_ have $hnthe $hnmost $hnrapid $hnonset $hnof $hnaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: $hnd
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

12. Ionization $hnof $hna $hndrug $hndepends $hnon $hnthe of $hnthe $hnsolution $hnand $hnthe of
$hnthe $hndrug.

a. pH; $hnpKa
b. pKa; $hnpH
c. concentration; $hnlipid $hnsolubility
d. pH; $hnconcentration
Answer: $hna
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

13. The $hnabsorption $hnof $hna $hndrug $hndepends $hnon $hnall $hnof $hnthe $hnfollowing $hnexcept
a. lipid $hnsolubility.
b. ionization.
c. body $hntemperature.
d. the $hnconcentration $hnof $hnthe $hndrug.
Answer: $hnc
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

14. Drugs $hnthat $hnare should $hnbe $hnavoided $hnby $hnwomen $hnof $hnchildbearing $hnage.
a. teratogenic
b. able $hnto $hncross $hnthe $hnplacental $hnbarrier
c. psychoactive
d. highly $hnlipid-soluble
Answer: $hna
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

15. Agents $hnthat $hninduce $hndevelopmental $hnabnormalities $hnin $hna $hnfetus $hnare $hnknown $hnas
a. psychoactive $hndrugs.
b. illicit $hndrugs.
c. teratogens.
d. placental $hndrugs.
Answer: $hnc
Textbook $hnReference: $hnPharmacokinetic $hnFactors $hnDetermining $hnDrug $hnAction

16. Depot $hnbinding $hnis $hnsaid $hnto $hnoccur $hnwhen $hndrugs
a. bind $hnto $hntheir $hntarget $hnsites.



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