Test Bank - Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), 9781975222321, Chapter 1-61 All Chapters

Test Bank For Abrams’ Clinical Drug Therapy R
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ationales for Nursing Practice 13th Edition (Vers
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ion 2024/2025) Geralyn Frandsen
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,Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
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the expected effect for this prescription?
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A. Curative effect on symptoms de de de



B. Systemic effect on symptoms de de de



C. Local effect on symptoms de de de



D. Parenteral effect on symptoms de de de




ANS: B d e d e



Rationale: Drugs that produce systemic effects are taken into the body, circulated through
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the bloodstream to their sites of action in various body tissues, and eventually eliminated
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from the body. Curative agents are given to cure a disease process. In this
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case, paroxeti ne hydrochloride will control the symptoms but not cure the disorder.
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Drugs with local eff ects, such as sunscreen and local anesthetics, act mainly at the site of
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application. Paroxet ine hydrochloride is not administered parenterally. Parenteral
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agents are administered sub cutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 de de



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
de Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
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SoBdOifOieSd.TW
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.hCaOt Mi s another name for this type
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o
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f medication?
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A. Synthetic drug de



B. Semisynthetic drug de



C. Biotechnology drug de



D. Prototype drug de




ANS: B d e d e



Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their
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chemic al characteristics, more consistent in their effects, and less likely to produce
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allergic react ions. Biotechnology drugs involve manipulating DNA and RNA and
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recombining genes i nto hybrid molecules that can be inserted into living organisms.
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Prototype drugs are the f irst drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 de de de



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
de Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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3. Which classification applies to morphine?
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A. Central nervous system depressant de de de



B. Central nervous system stimulant de de de

,
, C. Anti-inflammatory
D. Antihypertensive
ANS: A d e d e



Rationale: Drugs are classified according to their effects on particular body systems, their
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therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
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rvous system depressant and will produce this effect in the client. A central nervous syste
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d m stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
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antihypertensive agent reduces blood pressure.
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PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
de Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember d e NOT: Multiple Choice
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4. A client is administered amoxicillin. The generic name of this medication belongs to
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whi ch drug group?
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A. Selective serotonin reuptake inhibitors de de de



B. Diuretics
C. Penicillins
D. ACE inhibitors de




ANS: C d e d e



Rationale: The generic namGeRoAfD teE
n SinBdO
icO
atS
esTt.hC
eOdrug group (e.g., drugs with generic
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nam es ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are
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medicatio
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ns that have antidepressant effects; SSRI is a broad classification, not a generic name.
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Diur etics are medications that increase urine output; diuretic is a broad classification, not
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a ge neric name. ACE inhibitor is the broad classification for the angiotensin receptor
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blockers, not the generic name.
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PTS: 1 REF: p. 3, Drug Names OBJ: 2 de de de



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
de Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand d e NOT: Multiple Choice
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service de de



B. Federal Trade Commission de de



C. Occupational Safety and Health Administration de de de de



D. Food and de




de Drug Administration ANS: Db6 de