NURS 307 Integrating Mental Health and
Addiction into Nursing -questions with 100%
correct answers
What does carrier proteins do? - CORRECT ANSWERS ✔✔They transport
neurotransmitters across cell membranes. Medications may block or inhibit
this transport.
What is psychopharmacology? - CORRECT ANSWERS ✔✔- Subspecialty of
pharmacology that includes medications affecting the brain and behaviour
used to treat psychiatric disorders including:
~ Antipsychotics, mood stabilizers, antidepressants,
antianxiety medications, stimulants
- It provides a basis for understanding specific biologic treatments of
psychiatric disorders
What are the four sites of action? Or, what are the targets of medications? -
CORRECT ANSWERS ✔✔- Receptors
- Ion channels
- Enzymes
- Carrier proteins
What are the two types of action in receptors? - CORRECT ANSWERS
✔✔Agonist - same biologic action
,Antagonist - opposite effect
What are the interactions with a receptor? - CORRECT ANSWERS
✔✔Selectivity: specific for a receptor
Affinity: degree of attraction
Intrinsic activity: ability to produce a biologic response once it is attached to
receptor
Which drug facilitates GABA (gamma-aminobutyric acid) neurotransmitter in
opening the chloride ion channel? - CORRECT ANSWERS ✔✔Benzodiazepine
What are enzymes - CORRECT ANSWERS ✔✔- These catalyze specific
biochemical reactions within cells and are targets for some drugs.
Ex) Monamine oxidase
- These may be inhibited to produce greater neurotransmitter effect by
medications from a group of antidepressants.
What is monoamine oxidase? - CORRECT ANSWERS ✔✔It is an enzyme that
breaks down most bioamine neurotransmitters such as Norephinephrine, DA,
and 5-HT (these neurotransmitters are important in mental health disorders)
What are carrier proteins? - CORRECT ANSWERS ✔✔They transport
neurotransmitters across cell membranes. Medications may block or inhibit
this transport.
,What is the efficacy of a drug? - CORRECT ANSWERS ✔✔Efficacy is the
maximum response achievable from a drug. Effectiveness refers to the ability
of the drug to produce a beneficial effect.
What is the potency of a drug? - CORRECT ANSWERS ✔✔A highly potent
drug (e.g., fentanyl, alprazolam, risperidone) evokes a given response at low
concentrations, while a drug of lower potency (meperidine, diazepam,
ziprasidone) evokes the same response only at higher concentrations. Higher
potency does not necessarily mean more side effects.
What are target symptoms? - CORRECT ANSWERS ✔✔measurable, specific
symptoms expected to improve with treatment
What is drug toxicity? - CORRECT ANSWERS ✔✔Drug level exceeds
therapeutic range
What is therapeutic index? - CORRECT ANSWERS ✔✔Ratio of a drug's toxic
level to the level that provides therapeutic benefits. High is safer than low.
What are the four components of pharmacokinetics? - CORRECT ANSWERS
✔✔absorption, distribution, metabolism, excretion
What is absorption? - CORRECT ANSWERS ✔✔- Movement from the site of
administration into the plasma
, What are the 3 forms of absorption? - CORRECT ANSWERS ✔✔Oral (tablet
and liquid) - decreased absorption
IM (intramuscular injection): short and long acting-schizophrenia
IV: rarely used
What is Bioavailability? - CORRECT ANSWERS ✔✔- A measure of the extent
of drug absorption for a given drug and route (from 0% to 100%).
- Amount of a drug that reaches systemic circulation unchanged
- Often used to compare one drug to another--usually the higher the
bioavailability, the better
What is distribution? - CORRECT ANSWERS ✔✔- transport of a drug by the
bloodstream to its site of action
- It reflects how easy it is for a drug to pass out of the systemic circulation and
move into other types of tissues
How are psychiatric drugs distributed? - CORRECT ANSWERS ✔✔The blood
brain barrier (most fat-soluble)
Factors affecting distribution - CORRECT ANSWERS ✔✔- Amount of blood
flow or perfusion within the tissue
- How lipophilic (fat-loving) the drug is (easier to pass through BBB)
- Anatomic barriers, such as the blood-brain barrier, that the drug must cross
Addiction into Nursing -questions with 100%
correct answers
What does carrier proteins do? - CORRECT ANSWERS ✔✔They transport
neurotransmitters across cell membranes. Medications may block or inhibit
this transport.
What is psychopharmacology? - CORRECT ANSWERS ✔✔- Subspecialty of
pharmacology that includes medications affecting the brain and behaviour
used to treat psychiatric disorders including:
~ Antipsychotics, mood stabilizers, antidepressants,
antianxiety medications, stimulants
- It provides a basis for understanding specific biologic treatments of
psychiatric disorders
What are the four sites of action? Or, what are the targets of medications? -
CORRECT ANSWERS ✔✔- Receptors
- Ion channels
- Enzymes
- Carrier proteins
What are the two types of action in receptors? - CORRECT ANSWERS
✔✔Agonist - same biologic action
,Antagonist - opposite effect
What are the interactions with a receptor? - CORRECT ANSWERS
✔✔Selectivity: specific for a receptor
Affinity: degree of attraction
Intrinsic activity: ability to produce a biologic response once it is attached to
receptor
Which drug facilitates GABA (gamma-aminobutyric acid) neurotransmitter in
opening the chloride ion channel? - CORRECT ANSWERS ✔✔Benzodiazepine
What are enzymes - CORRECT ANSWERS ✔✔- These catalyze specific
biochemical reactions within cells and are targets for some drugs.
Ex) Monamine oxidase
- These may be inhibited to produce greater neurotransmitter effect by
medications from a group of antidepressants.
What is monoamine oxidase? - CORRECT ANSWERS ✔✔It is an enzyme that
breaks down most bioamine neurotransmitters such as Norephinephrine, DA,
and 5-HT (these neurotransmitters are important in mental health disorders)
What are carrier proteins? - CORRECT ANSWERS ✔✔They transport
neurotransmitters across cell membranes. Medications may block or inhibit
this transport.
,What is the efficacy of a drug? - CORRECT ANSWERS ✔✔Efficacy is the
maximum response achievable from a drug. Effectiveness refers to the ability
of the drug to produce a beneficial effect.
What is the potency of a drug? - CORRECT ANSWERS ✔✔A highly potent
drug (e.g., fentanyl, alprazolam, risperidone) evokes a given response at low
concentrations, while a drug of lower potency (meperidine, diazepam,
ziprasidone) evokes the same response only at higher concentrations. Higher
potency does not necessarily mean more side effects.
What are target symptoms? - CORRECT ANSWERS ✔✔measurable, specific
symptoms expected to improve with treatment
What is drug toxicity? - CORRECT ANSWERS ✔✔Drug level exceeds
therapeutic range
What is therapeutic index? - CORRECT ANSWERS ✔✔Ratio of a drug's toxic
level to the level that provides therapeutic benefits. High is safer than low.
What are the four components of pharmacokinetics? - CORRECT ANSWERS
✔✔absorption, distribution, metabolism, excretion
What is absorption? - CORRECT ANSWERS ✔✔- Movement from the site of
administration into the plasma
, What are the 3 forms of absorption? - CORRECT ANSWERS ✔✔Oral (tablet
and liquid) - decreased absorption
IM (intramuscular injection): short and long acting-schizophrenia
IV: rarely used
What is Bioavailability? - CORRECT ANSWERS ✔✔- A measure of the extent
of drug absorption for a given drug and route (from 0% to 100%).
- Amount of a drug that reaches systemic circulation unchanged
- Often used to compare one drug to another--usually the higher the
bioavailability, the better
What is distribution? - CORRECT ANSWERS ✔✔- transport of a drug by the
bloodstream to its site of action
- It reflects how easy it is for a drug to pass out of the systemic circulation and
move into other types of tissues
How are psychiatric drugs distributed? - CORRECT ANSWERS ✔✔The blood
brain barrier (most fat-soluble)
Factors affecting distribution - CORRECT ANSWERS ✔✔- Amount of blood
flow or perfusion within the tissue
- How lipophilic (fat-loving) the drug is (easier to pass through BBB)
- Anatomic barriers, such as the blood-brain barrier, that the drug must cross
