MSN 622 - HASHIMOTO THYROIDITIS
What is hashimoto thyroiditis? - Answers :autoimmune disease that destroys thyroid
cells by cell and antibody-mediated immune processes
What is the most common cause of hypothyroidism in developed countries? - Answers
:hashimoto
Describe the pathology of hasimotos... - Answers :formation of antithyroid antibodies
that attack the thyroid tissue, causing progressive fibrosis
What are the most common labs found in hashimotos? - Answers :elevated thyroid-
stimulating hormone (TSH) and low levels of free thyroxine (fT4), coupled with
increased antithyroid peroxidase (TPO) antibodies
What is conventional treatement of hashimotos? - Answers :levothyroxine 1.6-
1.8mcg/kg/day
What is the most common thyroid antigen that patients may develop antibodies to in
hashimotos? - Answers :anti-thyroid peroxidase
The development of hashimotos disease is thought to be of what origin? - Answers
:autoimmune origin with lymphocyte infiltration and fibrosis as typical features
What type of symptoms might patients see in early phase of hashimotos? late phase? -
Answers :- early: hyperthyroidism
- late: hypothyroidism
What are the classic skin symptoms associated with hashimotos? - Answers :-
myxedema (severe cases)
- scaly and dry skin
- epidermal thinning
- pale skin
- slow hair growth
- dry, coarse, dull, and brittle hair
- diffuse or partial alopecia
What cardiac/respiratory symptoms can be seen with hashimotos? - Answers :-
bradycardia
- fatigue
- exertional dyspnea
- exercise intolerance
What are some early symptoms that are commonly seen in hashimotos? - Answers :-
constipation
What is hashimoto thyroiditis? - Answers :autoimmune disease that destroys thyroid
cells by cell and antibody-mediated immune processes
What is the most common cause of hypothyroidism in developed countries? - Answers
:hashimoto
Describe the pathology of hasimotos... - Answers :formation of antithyroid antibodies
that attack the thyroid tissue, causing progressive fibrosis
What are the most common labs found in hashimotos? - Answers :elevated thyroid-
stimulating hormone (TSH) and low levels of free thyroxine (fT4), coupled with
increased antithyroid peroxidase (TPO) antibodies
What is conventional treatement of hashimotos? - Answers :levothyroxine 1.6-
1.8mcg/kg/day
What is the most common thyroid antigen that patients may develop antibodies to in
hashimotos? - Answers :anti-thyroid peroxidase
The development of hashimotos disease is thought to be of what origin? - Answers
:autoimmune origin with lymphocyte infiltration and fibrosis as typical features
What type of symptoms might patients see in early phase of hashimotos? late phase? -
Answers :- early: hyperthyroidism
- late: hypothyroidism
What are the classic skin symptoms associated with hashimotos? - Answers :-
myxedema (severe cases)
- scaly and dry skin
- epidermal thinning
- pale skin
- slow hair growth
- dry, coarse, dull, and brittle hair
- diffuse or partial alopecia
What cardiac/respiratory symptoms can be seen with hashimotos? - Answers :-
bradycardia
- fatigue
- exertional dyspnea
- exercise intolerance
What are some early symptoms that are commonly seen in hashimotos? - Answers :-
constipation
