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Mastering HESI Pharmacology: 50 Essential MCQs with Rationale”

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“Mastering HESI Pharmacology: 50 Essential MCQs with Rationale” Engaging Description Prepare to ace your HESI Pharmacology exam with this comprehensive set of 50 multiple-choice questions—each accompanied by a clear, concise rationale. Designed for nursing students and HESI candidates, this collection covers key drug classes, mechanisms, adverse effects, and nursing considerations. Sharpen your understanding, reinforce critical concepts, and boost your confidence before test day! Top 5 Hashtags #HESI Best Hashtags #Pharmacology Best Hashtags #NursingStudent Best Hashtags #PharmacologyMCQ Display Purposes #ExamPrep

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1–10: Cardiovascular Agents
1. Atenolol is prescribed for a patient with
hypertension. Which assessment is most
important before administering?
o A. Serum potassium
o B. Heart rate
o C. Respiratory rate
o D. Urine output
Answer: B. Heart rate
Rationale: Atenolol is a β₁-selective blocker that
slows conduction through the AV node; hold if
pulse <60 bpm (Registered Nurse RN).
2. A patient on furosemide reports muscle cramps
and weakness. Which lab value should the nurse
check?
o A. Sodium
o B. Calcium
o C. Potassium
o D. Magnesium
Answer: C. Potassium
Rationale: Furosemide causes renal K⁺ loss
leading to hypokalemia and muscle symptoms
(OpenStax).

,3. Which instruction should the nurse give for
spironolactone therapy?
o A. “Take with grapefruit juice.”
o B. “Report menstrual irregularities.”
o C. “Expect increased urine output.”
o D. “Avoid foods high in potassium.”
Answer: B. “Report menstrual irregularities.”
Rationale: Spironolactone can cause endocrine
effects like gynecomastia and menstrual changes
(nursingtip.com).
4. A patient receives nitroglycerin IV for chest pain.
What is the primary nursing action?
o A. Monitor BP every 5 minutes
o B. Check liver function tests
o C. Assess deep tendon reflexes
o D. Auscultate lung sounds
Answer: A. Monitor BP every 5 minutes
Rationale: Nitroglycerin causes vasodilation and
hypotension; frequent BP checks are essential
(nursingtip.com).
5. Which teaching point is essential for enalapril
therapy?
o A. “Rise slowly to avoid dizziness.”
o B. “Take on an empty stomach.”

, o C. “Expect a dry mouth.”
o D. “Limit fluid intake to 1 L/day.”
Answer: A. “Rise slowly to avoid dizziness.”
Rationale: ACE inhibitors can cause first-dose
hypotension and orthostatic dizziness
(nursingtip.com).
6. A patient on amiodarone develops visual halos.
What is the priority action?
o A. Obtain an ECG
o B. Check thyroid function
o C. Assess visual acuity
o D. Hold the drug and notify provider
Answer: D. Hold the drug and notify provider
Rationale: Amiodarone can cause optic
neuropathy; halos signal toxicity (nursingtip.com).
7. Which lab should the nurse monitor with warfarin
therapy?
o A. aPTT
o B. PT/INR
o C. Platelet count
o D. D-dimer
Answer: B. PT/INR
Rationale: PT/INR measures warfarin’s
anticoagulant effect (nursingtip.com).

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