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NUR 611 EXAM 2 REVIEW NOTES ALREADY A+ GRADED WITH EXPERT FEEDBACK|LATEST UPDATE |BRAND NEW!

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NUR 611 EXAM 2 REVIEW NOTES ALREADY A+ GRADED WITH EXPERT FEEDBACK|LATEST UPDATE |BRAND NEW!

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NUR 611 EXAM 2 REVIEW NOTES
ALREADY A+ GRADED WITH
EXPERT FEEDBACK|LATEST
UPDATE |BRAND NEW!

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Terms in this set (65)

, 1. Innate immunity includes two lines
of defense: natural barriers and
inflammation. Natural barriers are
physical, mechanical, and
biochemical barriers at the body's
surface, and they have been in place
since birth.
2. If the surface barriers are
What is the
breached, the second line of
purpose of the
defense--inflammatory response, is
inflammatory
activated to protect the body from
process?
further injury, prevent infection, and
promote healing.
3. The inflammatory response is a
rapid activation of biochemical and
cellular processes that is relatively
nonspecific, with a similar response
being initiated against a wide variety
of causes of tissue damage.

What are the Inflammation occurs in tissue that
FOUR cardinal has a blood supply (vascularized)
signs of and results in observable signs:
inflammation? redness, heat, swelling, and pain.

, Increased blood flow and capillary
permeability result in plasma
What is edema? leakage from vessels, causing
swelling (edema) in the surrounding
tissue.

The increased blood flow and
increasing concentration of red cells
Warmth and
at the site of inflammation cause
redness in
locally increased warmth and
inflammation
redness. Leukocytes adhere to
vessel walls.

At the same time, biochemical
mediators (histamine, bradykinins,
leukotrienes, prostaglandins)
Pain in
stimulate endothelial cells that line
inflammation
capillaries and venules to retract,
creating spaces at junctions
between cells.

Biochemical substance that attracts
Chemotactic
leukocytes to the site of
factor
inflammation

, The destruction of microorganisms
and cellular debris.


Once a phagocytic cell enters the
inflammatory site, the process of
phagocytosis involves four steps:


1) opsonization--recognition of the
Phagocytosis target, and adherence of the
phagocyte to it.
2) engulfment--ingestion or
endocytosis, and formation of
phagosome
3) fusion with lysosomal granules
within the phagocyte
(phagolysosome)
4) destruction of the target

All the local manifestations of acute
inflammation (ex, swelling, pain,
Local heat, and redness) result from
inflammation vascular changes and the
subsequent leakage of circulating
components into the tissue.

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