Exam 1: MH701 / MH 701 (Latest
) Psychopharmacologic /
Neuroscience Foundations of Mental
Health Care | Questions and
Answers | 100% Correct - Frontier
Question:
Pharmacokinetics
Answer:
The process by which drugs are absorbed, distributed within the body,
metabolized, and excreted.
Question:
Pharmacodynamics
Answer:
The process by which a medication works on the body. (Mechanisms of
action, time course and intensity of drug action or response)
,Question:
Half life
Answer:
Time taken for the plasma concentration of a drug to reduce to half its
original concentration; measures how long it takes for the drug to be removed
from the body (Especially important with respect to frequency of dosing; in
psychiatry when trying to discontinue a medication this is important to
understand) - eg short half life may lead to greater symptoms - ex: paroexinte
and SNRIs (venlafaxine, duloxetin; Fluvoxmine)
generally takes 4-5 half lives to be cleared from body
Question:
therapeutic index
Answer:
A ratio that compares the blood concentration at which a drug becomes toxic
and the concentration at which the drug is effective. (Lithium has small
therapeutic window where the therapeutic range is very close to the toxic
range)
, Question:
Agonist
Answer:
a molecule that, by binding to a receptor site, stimulates a response (Binds
and causes a change)
Question:
Antagonist
Answer:
Binds and prevents the receptor from having a response
Question:
CYP enzymes associated with Psychiatric medications
Answer:
1A2, 2D6, 3A4 (and sometimes 2C19); all psychiatric medications are
metabolized by the liver so most interact with these enzymes
) Psychopharmacologic /
Neuroscience Foundations of Mental
Health Care | Questions and
Answers | 100% Correct - Frontier
Question:
Pharmacokinetics
Answer:
The process by which drugs are absorbed, distributed within the body,
metabolized, and excreted.
Question:
Pharmacodynamics
Answer:
The process by which a medication works on the body. (Mechanisms of
action, time course and intensity of drug action or response)
,Question:
Half life
Answer:
Time taken for the plasma concentration of a drug to reduce to half its
original concentration; measures how long it takes for the drug to be removed
from the body (Especially important with respect to frequency of dosing; in
psychiatry when trying to discontinue a medication this is important to
understand) - eg short half life may lead to greater symptoms - ex: paroexinte
and SNRIs (venlafaxine, duloxetin; Fluvoxmine)
generally takes 4-5 half lives to be cleared from body
Question:
therapeutic index
Answer:
A ratio that compares the blood concentration at which a drug becomes toxic
and the concentration at which the drug is effective. (Lithium has small
therapeutic window where the therapeutic range is very close to the toxic
range)
, Question:
Agonist
Answer:
a molecule that, by binding to a receptor site, stimulates a response (Binds
and causes a change)
Question:
Antagonist
Answer:
Binds and prevents the receptor from having a response
Question:
CYP enzymes associated with Psychiatric medications
Answer:
1A2, 2D6, 3A4 (and sometimes 2C19); all psychiatric medications are
metabolized by the liver so most interact with these enzymes
