NURS6630 ///NURS 6630
PSYCHOPHARMACOLOGY MIDTERM EXAM 2
VERSIONS ACTUAL MIDTERM EXAM SUMMER
QRT| MOST RECENT WALDEN
UNIVERSITY|AGRADED
Serotonin regulates Correct Answer Mood, emotion, feeding, and
reproductive behavior
This class of antidepressants binds to presynaptic SERT and
inhibits them from reuptake of serotonin to increase levels in the
synaptic cleft to bind with postsysnaptic 5HT2 receptors Correct
Answer SSRIs
First line therapy for MDD due to milder side effect profiles
Correct Answer SSRIs
Six Common SSRIs Correct Answer citalopram, escitalopram,
fluoxetine, fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs Correct Answer 4-6
weeks
,In addition to MDD, SSRIs also treat Correct Answer Chronic
Anxiety, PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include Correct Answer
Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25
years old Correct Answer suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.) Correct Answer Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of
the nervous system Correct Answer Serotonin Syndrome
Seven symptoms of Serotonin Syndrome Correct Answer
Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome Correct Answer
Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by Correct Answer
blocking 5-HT2 receptors (serotonin antagonist)
, When SSRIs or SNRIs are stopped abruptly, common symptoms
of withdrawal include Correct Answer Irritability, headaches, and
insomnia
Medicine specific side effect of citalopram Correct Answer
Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with
congenital heart defects Correct Answer Paroxetine
All SSRIs but paroxetine (D) are pregnancy category Correct
Answer C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes
Correct Answer fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include Correct Answer duloxetine,
venlafaxine, desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft Correct Answer SNRIs
PSYCHOPHARMACOLOGY MIDTERM EXAM 2
VERSIONS ACTUAL MIDTERM EXAM SUMMER
QRT| MOST RECENT WALDEN
UNIVERSITY|AGRADED
Serotonin regulates Correct Answer Mood, emotion, feeding, and
reproductive behavior
This class of antidepressants binds to presynaptic SERT and
inhibits them from reuptake of serotonin to increase levels in the
synaptic cleft to bind with postsysnaptic 5HT2 receptors Correct
Answer SSRIs
First line therapy for MDD due to milder side effect profiles
Correct Answer SSRIs
Six Common SSRIs Correct Answer citalopram, escitalopram,
fluoxetine, fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs Correct Answer 4-6
weeks
,In addition to MDD, SSRIs also treat Correct Answer Chronic
Anxiety, PTSD, OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include Correct Answer
Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25
years old Correct Answer suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.) Correct Answer Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of
the nervous system Correct Answer Serotonin Syndrome
Seven symptoms of Serotonin Syndrome Correct Answer
Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome Correct Answer
Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by Correct Answer
blocking 5-HT2 receptors (serotonin antagonist)
, When SSRIs or SNRIs are stopped abruptly, common symptoms
of withdrawal include Correct Answer Irritability, headaches, and
insomnia
Medicine specific side effect of citalopram Correct Answer
Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with
congenital heart defects Correct Answer Paroxetine
All SSRIs but paroxetine (D) are pregnancy category Correct
Answer C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes
Correct Answer fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include Correct Answer duloxetine,
venlafaxine, desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft Correct Answer SNRIs
