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Class notes Biochemistry (BIOSC1000)

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These clear and concise biochemistry notes cover foundational topics essential for any introductory biochem course. Perfect for exam prep, studying, or quick refreshers! Topics Included: Biological Molecules: Overview of carbohydrates, lipids, nucleic acids, and amino acids Chemical Bonds & Interactions: Covalent, ionic, hydrogen bonding, van der Waals forces, hydrophobic interactions pH & Buffers: The concept of pH, the Henderson-Hasselbalch equation, buffer systems in the body (e.g., bicarbonate), and how to calculate pH and pKa Protein Structure: Levels of structure (primary, secondary, tertiary, quaternary), peptide bonding, alpha helices, beta sheets, and the importance of protein folding These notes are organized, easy to follow, and designed to help you understand core concepts quickly. Ideal for undergraduates taking general or introductory biochemistry courses.

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Uploaded on
May 6, 2025
Number of pages
100
Written in
2024/2025
Type
Class notes
Professor(s)
Laura zapanta
Contains
1 to 6

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,Biosc 1000 Spring 2025 1/9/2025




Lesson 1 - Molecular Interactions

Learning Objectives
You should be able to:
• Know that biological molecules are made up of a small number of possible elements
• Recognize common functional groups in biological molecules
• Differentiate between covalent bonds and noncovalent interactions.
• Describe the characteristics of common weak, noncovalent interactions in biological
molecules.
• Identify hydrogen bond donors and hydrogen bond acceptors.
• Name the four major classes of macromolecules found in living organisms and identify
the constituents of those that are polymeric

Textbook Reference
Chapter 1, Section 2 (pp. 8-15) and Section 3 (pp. 24-26)
Chapter 2, Section 2 (pp. 61-67)

Vocabulary
• element
• atom
• molecule
• compound
• valence electron
• covalent bond
• ionic bond
• hydrophilic
• hydrophobic
• electronegativity
• polar covalent bond
• functional groups

Lecture Slides (begin next page)




This material is for the use of Dr. Zapanta's Spring 2025 Biosc 1000 students only and cannot be distributed
electronically, in print, or posted on any electronic forum. Doing so is a breach of academic integrity and will be
prosecuted as such.




©2025 Laura S. Zapanta, Ph.D. 1

,Biosc 1000 Spring 2025 1/9/2025




Molecular Interactions




Organization in living systems displays a
structural hierarchy.




©2025 Laura S. Zapanta, Ph.D. 2

, Biosc 1000 Spring 2025 1/9/2025




Biochemistry is the study of living things at
biodum
the molecular level.
=
molecular


living things
basis of




Four major elements make up ~90% of living >
matter.

j
f
S




©2025 Laura S. Zapanta, Ph.D. 3
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