Infection Meds
Antibiotics
- Penicillin
• Assess for allergies, Steven Johnson Syndrome, kidney function,
take an empty stomach, no alcohol, use 2nd form of birth control,
photosensitivity
- Cephalosporin
• Allergy (PCN cousin), interacts with warfarin, use 2nd form of birth
control, assess for renal function, no alcohol, photo sensitivity,
empty stomach
- Macrolides “Thromycin”
• Prolonged QT waves liver toxicity, empty stomach, baseline
cardiac, and LFTs
- Tetracycline
• NOT for kids under 8 years old, due to teeth problems and skeletal
problems, photosensitivity, sit up for 30 minutes after taking,
interacts with dairy
- Sulfonamides “sulfa in the water tank”
• Assess for sulfa allergy, monitor kidneys, prone for kidney stones
and crystals, Steven Johnson Syndrome, drink 1- 2 L of fluid each
day
- Aminoglycosides (Gentamycin, Neomycin)
• Otoxicity and nephrotoxicity (Oto = irreversible) (nephron =
reversible), draw peak 30 minutes after administration, trough 30
min before next dose, never mix with penicillin
- Quinolones “Quinn takes pictures of her bones and tendons”
• Phototoxicity, contraindicated with tendon rupture, increase PO
intake, Cipro needs to be in own IV
- Metronidazole
, • Use for bacterial vaginosis CDiV, Steven Johnson syndrome
interact with phenytoin and phenobarbital, induces
thrombocytopenia
- Vancomycin
• RED MAN SYNDROME, administer over 1 hr, Otoxicity and
nephrotoxicity (Oto = irreversible) (nephron = reversible),
Thrombophlebitis
Lupus Medications
Antimalarial
- Hydrocloroquine “Eye droxycloroquine”
• Risk for retinopathy need eye exam every 6 months
Antileprosy
- Dapsone
• BMS, GI eVects
Corticosteroids
- Methylprednisolone, Prednisone
• Not for long-term use, may increase blood glucose, increased
infection risk
Immunosuppressants
- Methotrexate “Meth – NO – Trexate”
• No pregnancy, infection risk, increased risk of cancer, no live
vaccines
- Azathioprine (Imuran)
- Cyclophosphamide (Cytoxan)
- Belimumab “medicate with monoclonal”
• Pre-medicate with Tylenol and Benadryl
, Immunosuppressant Drugs
- Azathioprine (Imuran)
• BMS
- Cyclosporine (Sandimmune)
• Narrow therapeutic range, increased risk for infection, neurotoxic,
hepatotoxic, nephrotoxic
- Mycophenolate (Cellcept)
• Increased risk for congenital malformation, infection risk
- Tacrolimus (Prograf)
• Monitor drug levels
HIV / AIDS medication
Reverse Transcriptase Inhibitors
- Nevirapine (Viramune)
• LFTs, Steven Johnson syndrome
- Tenofovir (Viread)
- Zidovudine (Retrovir) aka Azidothymidine “Last in the alphabet, 1st to
treat”
• 1st most common, BMS, must remain upright for 30 minutes after
oral dose to prevent esophageal ulceration
Protease Inhibitors
- Indinavir (Cixivan) & Ritonavir (Norvir)
• Encourage at least 48 ounces of fluid / day, side eVect of
osteoporosis so patients need to take calcium and vitamin D and
be weight-bearing, use 2nd form of birth control
Fusion Inhibitors
- Enfuvirtide (Fuzeon)
• Injectable only, rotate sites
Antibiotics
- Penicillin
• Assess for allergies, Steven Johnson Syndrome, kidney function,
take an empty stomach, no alcohol, use 2nd form of birth control,
photosensitivity
- Cephalosporin
• Allergy (PCN cousin), interacts with warfarin, use 2nd form of birth
control, assess for renal function, no alcohol, photo sensitivity,
empty stomach
- Macrolides “Thromycin”
• Prolonged QT waves liver toxicity, empty stomach, baseline
cardiac, and LFTs
- Tetracycline
• NOT for kids under 8 years old, due to teeth problems and skeletal
problems, photosensitivity, sit up for 30 minutes after taking,
interacts with dairy
- Sulfonamides “sulfa in the water tank”
• Assess for sulfa allergy, monitor kidneys, prone for kidney stones
and crystals, Steven Johnson Syndrome, drink 1- 2 L of fluid each
day
- Aminoglycosides (Gentamycin, Neomycin)
• Otoxicity and nephrotoxicity (Oto = irreversible) (nephron =
reversible), draw peak 30 minutes after administration, trough 30
min before next dose, never mix with penicillin
- Quinolones “Quinn takes pictures of her bones and tendons”
• Phototoxicity, contraindicated with tendon rupture, increase PO
intake, Cipro needs to be in own IV
- Metronidazole
, • Use for bacterial vaginosis CDiV, Steven Johnson syndrome
interact with phenytoin and phenobarbital, induces
thrombocytopenia
- Vancomycin
• RED MAN SYNDROME, administer over 1 hr, Otoxicity and
nephrotoxicity (Oto = irreversible) (nephron = reversible),
Thrombophlebitis
Lupus Medications
Antimalarial
- Hydrocloroquine “Eye droxycloroquine”
• Risk for retinopathy need eye exam every 6 months
Antileprosy
- Dapsone
• BMS, GI eVects
Corticosteroids
- Methylprednisolone, Prednisone
• Not for long-term use, may increase blood glucose, increased
infection risk
Immunosuppressants
- Methotrexate “Meth – NO – Trexate”
• No pregnancy, infection risk, increased risk of cancer, no live
vaccines
- Azathioprine (Imuran)
- Cyclophosphamide (Cytoxan)
- Belimumab “medicate with monoclonal”
• Pre-medicate with Tylenol and Benadryl
, Immunosuppressant Drugs
- Azathioprine (Imuran)
• BMS
- Cyclosporine (Sandimmune)
• Narrow therapeutic range, increased risk for infection, neurotoxic,
hepatotoxic, nephrotoxic
- Mycophenolate (Cellcept)
• Increased risk for congenital malformation, infection risk
- Tacrolimus (Prograf)
• Monitor drug levels
HIV / AIDS medication
Reverse Transcriptase Inhibitors
- Nevirapine (Viramune)
• LFTs, Steven Johnson syndrome
- Tenofovir (Viread)
- Zidovudine (Retrovir) aka Azidothymidine “Last in the alphabet, 1st to
treat”
• 1st most common, BMS, must remain upright for 30 minutes after
oral dose to prevent esophageal ulceration
Protease Inhibitors
- Indinavir (Cixivan) & Ritonavir (Norvir)
• Encourage at least 48 ounces of fluid / day, side eVect of
osteoporosis so patients need to take calcium and vitamin D and
be weight-bearing, use 2nd form of birth control
Fusion Inhibitors
- Enfuvirtide (Fuzeon)
• Injectable only, rotate sites
