A CLINICAL APPROACH, 4TH EDITION COMPLETE
NEWEST VERIFIED VERSION
1.chemotherapeutic drug - answer any chemical used in the treatment, relief, or
prophylaxis of a disease
2.prophylaxis - answer drug to prevent imminent infection of a person at risk
3.antimicrobial chemotherapy - answer chemotherapeutic drugs to control
infection
4.antimicrobials - answer any antimicrobial drug, regardless of its origin
5.antibiotics - answer inhibitor destroy other microogranisms
6.semisynthetic drugs - answer chemically modified drugs
7.synthetic drugs - answer produced entirely by chemical reactions
8.narrow spectrum - answer effective against a LIMITED array of microbial types
9.broad spectrum - answer effective against a WIDE variety of microbial types
,10.Disease - answer any deviation from health
11.Factors that cause diseases - answer infections, diet, genetics and aging
12.infectious disease - answer the disruption of a tissue or organ caused by
microbes or their products
13.Stages of host-parasite relationship - answer contact progresses to infection
and infection ends in disease.
14.Contamination without colonization and colonization without disease are the
rules. - answer ...normal (resident) biota - answer the large and mixed collection
of microbes adapted to the bod has been variously called the ____ ____. Some
microbiologists also prefer to use the term NORMAL FLORA.
15.Normal (resident) Biota - answer bacteria, fungi, protozoa, and to a certain
extent, viruses and arthropods are ____ ____.
16.metagenomics - answer there are more unknown than known species that
populate the human body. ______ is an effort to identify the microbial profile
inside and on humans.
17.The Human Microbiome Project - answer Began in 2007, is funded by the
national institutes of health and is being conducted at labrotories all over the
country. The aim is to collect genetic sequenes in he gut, respiratory tract, skin
and so on , to determine which microbes are there even when they can't be
, grown in a labrotory. A secondary aim is to determine what role these normal
biota play in health and disease
18.Sites that harbor a Known Normal Biota - answer Skin and its adjacent
mucous membranes
> Respiratory Tract
> Gastrointestinal Tract (various Parts)
> Outer Opening of Urethra
> External Genitalia
> Vagina
> External Ear Canal
> External Eye (lids, conjunctiva)
19.Anatomical Sites and Fluids thought to be Sterile - answer All Internal Tissues
and Organs: Heart & Circulatory System, Liver, Kidneys and Bladder, Brain and
Spinal Cord, Muscles, Bones, Ovaries/testes, Glands (Pancreas, salivary, thyroid)
Sinuses, Middle and Inner Ear, Internal Eye
> Fluids within an organ or tissue:
Blood, Urine in Kidneys, ureters, bladder. Cerebrospinal Fluid, Saliva prior to
entering the Oral Cavity, Semen prior to entering the Urethra, Amniotic Fluid
surrounding the embryo and fetus only a small percentages of microbes that
come in contact with the human body are able to colonize a particular area. Most
are destroyed by the hosts defenses. - answer Although generally stable, the biota
can fluctuate to a limited extent with general health age, variations in diet,
hygiene, hormones, drug therapy.