Chapter 01: Introduction g g
Celentano: Gordis Epidemiology, 6th Edition g g g g
g Test Bank g
MULTIPLE CHOICE g
1. Which of the following is an example of tertiary prevention?
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a. Vaccination for rotavirus for children younger than the age of 1 year g g g g g g g g g g g
b. Surgical amputation of an extremity with osteosarcoma (bone cancer)
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c. Screening for gestational diabetes after 24 weeks of pregnancy
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d. Sexual education program in elementary schools
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e. Increasing taxes for buying cigarettes g g g g
ANS: B
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Surgical amputation of an extremity with osteosarcoma (bone cancer) is an example in which
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when a disease is present the treatment (amputation) is done to reduce the impact of disease
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by preventing the tumor from dissemination. Vaccination for rotavirus for children younger
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than the age of 1 year, sexual education program in elementary schools, and increasing taxes
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for buying cigarettes represent examples of primary prevention. Screening for gestational
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diabetes after 24 weeks of pregnancy is an example of secondary prevention.
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2. This historic character obs ervedNtU
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mMortalit y was more common among
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women treated by physicians and medical students compared with women treated by
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midwives. Based on his observations, he implemented a hand wash policy that resulted in a
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decrease in mortality. Name the character that we are talking about.
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a. John Snow g
b. Edward Jenner g
c. D.A. Henderson g
d. Leon Gordis g
e. Ignaz Semmelweis g
ANS: E
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Ignaz Semmelweis identified that medical students and physicians transmitted the disease by
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gnot washing their hands after examining bodies at autopsies and conducting multiple
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gexaminations in the clinic. g g g
3. Thanks to the contributions of Edward Jenner, the following disease was eradicated later
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by efforts organized by D.A. Henderson:
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a. Cholera
b. Smallpox
c. Chickenpox
d. Polio
e. Zika
,ANS: B g
Smallpox was eradicated in 1980. Edward Jenner vaccinated James Phipps in 1796 against
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smallpox. Almost 200 years later, the World Health Organization (WHO) commissioned
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D.A. Henderson to lead the efforts to eradicate the disease.
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4. Over the past century, a marked decline in the mortality rates of many infectious diseases
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has been observed. Which of the following is the most likely reason for the observed decline
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in mortality rates from common infectious diseases?
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a. Development of penicillin g g
b. Development of insulin g g
c. Development of vaccines g g
d. Improvement in social conditions g g g
e. Worse sanitation and unsafe water
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ANS: D
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Although medical treatments potentially helped in the decrease of infectious diseases, the
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advancement in social conditions played a major role. These improvements include better
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sanitation, safe disposal of waste, better nutrition, and improvement in housing conditions.
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, Chapter 02: The Dynamics of Disease Transmission g g g g g g
Celentano: Gordis Epidemiology, 6th Edition g g g g
g MULTIPLE CHOICE g
1. Which term most accurately describes the following definition? “The occurrence in a
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community or region of cases of an illness, specific health-related behavior, or other health-
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related events clearly in excess of normal expectancy.” [Porta M, ed. A Dictionary of
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gEpidemiology. New York: Oxford University Press; 2014.] g g g g g g
a. Endemic
b. Epidemic
c. Pandemic
d. Attack rate g
e. Incubation period g
ANS: B
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An epidemic is the occurrence of health-related events in a community or region, in clear
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excess of normal expectation. Endemic is not true because it is defined as the constant
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occurrence of a disease, disorder, or noxious infectious agent in a geographic area or
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population group. Pandemic is not true because it is defined as an epidemic occurring over a
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very wide area, crossing internationU
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people. Attack rate is not true because it is defined as number of people at risk in whom a
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certain illness develops over total number of people at risk. Incubation period is not true
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because it is the interval from receipt of infection to the time of onset of clinical illness (the
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onset of recognizable symptoms).
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2. What is the most accurate definition of the incubation period (of an infectious disease)?
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a. The time of onset of clinical illness or the onset of recognizable symptoms
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b. The interval from receipt of infection to the time of onset of clinical illness (the onset of
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recognizable symptoms)
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c. The time of invasion by an infectious agent
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d. The time between initiation of infection and first shedding or excretion of the agent
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e. The period between exposure and the onset of infectiousness
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ANS: B
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The incubation period is defined as the interval from receipt of infection to the time of onset
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of clinical illness (the onset of recognizable symptoms); in other words, the time between the
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moment of developing symptoms and the moment of invasion by an infectious agent. “The
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time of onset of clinical illness or the onset of recognizable symptoms” is not true as it
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corresponds to “time of onset.” “The time of invasion by an infectious agent” is not true as it
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corresponds to “time of infection.” “The time between initiation of infection and first
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shedding or excretion of the agent” and “The period between exposure and the onset of
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infectiousness” are not true as they correspond to the latent period. (The latent period is
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