Nurs 4800 Exam 2 Psychopharmacology I
Questions With Complete Solutions
Absorption Correct Answers the movement of the
drug from the site of administration into the
plasma
Adverse reactions Correct Answers unwanted
effects with serious physiologic consequences
Affinity Correct Answers the degree of attraction
or strength of the bond between the drug and its
biologic target
^ chemical bonds = ^ affinity
Agonists Correct Answers mimic
neurotransmitters
increase activity
stimulate *post*synaptic receptors to use *more
neurotransmitters*
Antagonists Correct Answers block the receptor
block the *post*synaptic receptor so
neurotransmitter cannot act
Bioavailability Correct Answers the amount of the
drug that reaches systemic circulation unchanged
, Boxed warning Correct Answers Serious adverse
effects that can occur with the use of a specific
medication; noted in issued warning in the package
insert.
Carrier protein Correct Answers membrane
protein that transports a specific molecule across
the cell membrane
AKA uptake receptors
Clearance Correct Answers refers to the total
volume of blood, serum, or plasma from which a
drug is completely removed per unit of time to
account for excretion
Cytochrome P450 system (CYP450) Correct
Answers hepatic microsomal enzyme system
divided into subfamilies CYP1, CYP2, CYP3 who
have different affinities for metabolizing different
drugs
As a drug molecule is taken into the liver it is acted
upon by one of the CYP systems
Desensitization Correct Answers a rapid decrease
in drug effects that may develop in a few minutes
of exposure to a drug
Questions With Complete Solutions
Absorption Correct Answers the movement of the
drug from the site of administration into the
plasma
Adverse reactions Correct Answers unwanted
effects with serious physiologic consequences
Affinity Correct Answers the degree of attraction
or strength of the bond between the drug and its
biologic target
^ chemical bonds = ^ affinity
Agonists Correct Answers mimic
neurotransmitters
increase activity
stimulate *post*synaptic receptors to use *more
neurotransmitters*
Antagonists Correct Answers block the receptor
block the *post*synaptic receptor so
neurotransmitter cannot act
Bioavailability Correct Answers the amount of the
drug that reaches systemic circulation unchanged
, Boxed warning Correct Answers Serious adverse
effects that can occur with the use of a specific
medication; noted in issued warning in the package
insert.
Carrier protein Correct Answers membrane
protein that transports a specific molecule across
the cell membrane
AKA uptake receptors
Clearance Correct Answers refers to the total
volume of blood, serum, or plasma from which a
drug is completely removed per unit of time to
account for excretion
Cytochrome P450 system (CYP450) Correct
Answers hepatic microsomal enzyme system
divided into subfamilies CYP1, CYP2, CYP3 who
have different affinities for metabolizing different
drugs
As a drug molecule is taken into the liver it is acted
upon by one of the CYP systems
Desensitization Correct Answers a rapid decrease
in drug effects that may develop in a few minutes
of exposure to a drug
