NU150 EXAM 2 STUDY GUIDE
Adrenocortical Hormones - Answers :Prednisone
Posterior Pituitary - Answers :Master Gland
Posterior Pituitary regulates: - Answers :Vasopressin (ADH) and Oxytocin
Vassopressin (ADH) f(x) - Answers :Increases water reabsorption in kidneys, fluid
balance, and homeostasis
Vasopressin ADR - Answers :Water intoxication, brain cell swells, high Na+, same effect
as hypotonic solution, drowsiness
Adrenocorticotropic Hormone (ACTH) - Answers :Stimulates sugar, salt and sex
(glucocorticoids/cortisol, mineralcorticoids/aldosterone, andrgogens &
estrogens/testosterone)
Glucocorticoids (Cortisol) - Answers :affects metabolism: carbs, fats and proteins
Mineralcorticoids - Answers :affects water and electrolyte balance
Corticosteroids Uses - Answers :Adrenocortical insufficiency, allergic rxns, rheumatic
disease, resp. disease, shock
Corticosteroids suffix - Answers :-one
Cushing's Syndrome - Answers :Hypertension, moon face, buffalo hump, obese
Prednisone ADR - Answers :moon face; acute adrenal insufficiency
Addisone's Disease - Answers :Weak, weight loss, adrenal crisis, hypotension
Mineralocorticoids F(x) - Answers :Adds Na+, loses K+
Mineralocorticoid ADR - Answers :Addisonian Crisis; hypoglycemia, hypotension,
confusion, hyperkalemia, muscular weakness
Mineralocorticoid Pt. Teaching - Answers :Never stop abruptly, doses must be tapered
every other day, should not be taken more than 5 days
Thyroid Hormones - Answers :TRH, TSH, T3, T4
Thyroid Hormone F(x) - Answers :Increase metabolic rate of tissues; replacement
therapy in hypothyroidism
, Levothyroxine (Synthroid) - Answers :once a day dosage before breakfast; empty
stomach promotes full absorption
Thyroid Drugs ADR - Answers :Hyperthyroidism; hyperglycemia
Thyroid Drug Interactions - Answers :Don't mix with blood thinners; increased risk for
bleeding
Thyroid Drug - Answers :Levothyroxine
Thyroid Hormone Pt. Teaching - Answers :Lifetime treatment, do not self-dose, take in
AM before breakfast, report S/S of hypothyroidism, TSH levels monitored regularly
Antithyroid Drugs - Answers :propylthiouracil (PTU)
methimazole (tapazole)
Iodine compounds: decreases vascularity
Radioactive iodine: destroys hyperactive tissue
Full effect can take 3-4 weeks
Antithyroid ADR - Answers :PTU decreases WBCs (granulocytes)
Antithyroid Pt. Teaching - Answers :sore throat, fever, bruising, radioactive iodine
precautions, Thyroid replacement for hypothyroidism
Upper Respiratory Drugs - Answers :Antihistamine, Decongestant, Antitussive,
Expectorant, Mucolytic
Histamine - Answers :Produced in response to injury
F(x): dilation of arterioles (redness), increased permeability of capillaries and veins
(swelling); inflammatory response
Antihistamine Uses - Answers :Seasonal allergies, allergic rhinitis, allergic conjunctivitis,
relieves coughs from allergies, relieves uncomplicated urticaria, relieves allergic rxns to
meds or blood products
Antistamine MOA - Answers :Blocks Histamine (H1) receptors
1st gen: non selective CNS and peripheral (sedative effect)
2nd gen: selective (less sedative effect)
Antihistamine Drugs - Answers :Diphenhydramine (Benadryl)
Loratadine (Claritin)
Antihistamine ADR - Answers :drowsiness and sedation
Antihistamine Pt. Teaching - Answers :No driving, no alcohol
Adrenocortical Hormones - Answers :Prednisone
Posterior Pituitary - Answers :Master Gland
Posterior Pituitary regulates: - Answers :Vasopressin (ADH) and Oxytocin
Vassopressin (ADH) f(x) - Answers :Increases water reabsorption in kidneys, fluid
balance, and homeostasis
Vasopressin ADR - Answers :Water intoxication, brain cell swells, high Na+, same effect
as hypotonic solution, drowsiness
Adrenocorticotropic Hormone (ACTH) - Answers :Stimulates sugar, salt and sex
(glucocorticoids/cortisol, mineralcorticoids/aldosterone, andrgogens &
estrogens/testosterone)
Glucocorticoids (Cortisol) - Answers :affects metabolism: carbs, fats and proteins
Mineralcorticoids - Answers :affects water and electrolyte balance
Corticosteroids Uses - Answers :Adrenocortical insufficiency, allergic rxns, rheumatic
disease, resp. disease, shock
Corticosteroids suffix - Answers :-one
Cushing's Syndrome - Answers :Hypertension, moon face, buffalo hump, obese
Prednisone ADR - Answers :moon face; acute adrenal insufficiency
Addisone's Disease - Answers :Weak, weight loss, adrenal crisis, hypotension
Mineralocorticoids F(x) - Answers :Adds Na+, loses K+
Mineralocorticoid ADR - Answers :Addisonian Crisis; hypoglycemia, hypotension,
confusion, hyperkalemia, muscular weakness
Mineralocorticoid Pt. Teaching - Answers :Never stop abruptly, doses must be tapered
every other day, should not be taken more than 5 days
Thyroid Hormones - Answers :TRH, TSH, T3, T4
Thyroid Hormone F(x) - Answers :Increase metabolic rate of tissues; replacement
therapy in hypothyroidism
, Levothyroxine (Synthroid) - Answers :once a day dosage before breakfast; empty
stomach promotes full absorption
Thyroid Drugs ADR - Answers :Hyperthyroidism; hyperglycemia
Thyroid Drug Interactions - Answers :Don't mix with blood thinners; increased risk for
bleeding
Thyroid Drug - Answers :Levothyroxine
Thyroid Hormone Pt. Teaching - Answers :Lifetime treatment, do not self-dose, take in
AM before breakfast, report S/S of hypothyroidism, TSH levels monitored regularly
Antithyroid Drugs - Answers :propylthiouracil (PTU)
methimazole (tapazole)
Iodine compounds: decreases vascularity
Radioactive iodine: destroys hyperactive tissue
Full effect can take 3-4 weeks
Antithyroid ADR - Answers :PTU decreases WBCs (granulocytes)
Antithyroid Pt. Teaching - Answers :sore throat, fever, bruising, radioactive iodine
precautions, Thyroid replacement for hypothyroidism
Upper Respiratory Drugs - Answers :Antihistamine, Decongestant, Antitussive,
Expectorant, Mucolytic
Histamine - Answers :Produced in response to injury
F(x): dilation of arterioles (redness), increased permeability of capillaries and veins
(swelling); inflammatory response
Antihistamine Uses - Answers :Seasonal allergies, allergic rhinitis, allergic conjunctivitis,
relieves coughs from allergies, relieves uncomplicated urticaria, relieves allergic rxns to
meds or blood products
Antistamine MOA - Answers :Blocks Histamine (H1) receptors
1st gen: non selective CNS and peripheral (sedative effect)
2nd gen: selective (less sedative effect)
Antihistamine Drugs - Answers :Diphenhydramine (Benadryl)
Loratadine (Claritin)
Antihistamine ADR - Answers :drowsiness and sedation
Antihistamine Pt. Teaching - Answers :No driving, no alcohol
