TEST BANK GUIDE FOR LEHNE’S PHARMACOLOGY FOR NURSING CARE 11 TH EDITION
/QUESTION AND ANSWERS WELL EXPLAINED. Author: Jacqueline Burchum| Laura
,TABLE OF CONTENTS
UNIT I: INTRODUCTION ................................................................................................................................. 6
CHAPTER 01: ORIENTATION TO PHARMACOLOGY ................................................................................... 6
CHAPTER 02: APPLICATION OF PHARMACOLOGY IN NURSING PRACTICE ............................................... 8
CHAPTER 03: DRUG REGULATION, DEVELOPMENT, NAMES, AND INFORMATION................................ 16
UNIT II: BASIC PRINCIPLES OF PHAMACOLOGY .......................................................................................... 19
CHAPTER 04: PHARMACOKINETICS......................................................................................................... 19
CHAPTER 05: PHARMACODYNAMICS ..................................................................................................... 26
CHAPTER 06: DRUG INTERACTIONS ........................................................................................................ 30
CHAPTER 07: ADVERSE DRUG REACTIONS AND MEDICATION ERRORS ................................................. 37
CHAPTER 08: INDIVIDUAL VARIATION TO DRUG RESPONSES ................................................................ 43
CHAPTER 09: GENETIC AND GENOMIC CONSIDERATIONS ..................................................................... 49
CHAPTER 10: INTRODUCTION TO IMMUNOMODULATORS ................................................................... 53
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ....................................................................................... 57
CHAPTER 11: DRUG THERAPY DURING PREGNANCY AND BREAST-FEEDING ......................................... 57
CHAPTER 12: DRUG THERAPY IN PEDIATRIC PATIENTS .......................................................................... 62
CHAPTER 13: DRUG THERAPY IN OLDER ADULTS ................................................................................... 67
UNIT IV: PERIPHERALNERVOUS SYSTEM DRUGS ........................................................................................ 74
SECTION 1> INTRODUCTION ............................................................................................................... 74
CHAPTER 14: BASIC PRINCIPLES OF NEUROPHARMACOLOGY ............................................................... 74
CHAPTER 15: PHYSIOLOGY OF THE PERIPHERAL NERVOUS SYSTEM ...................................................... 78
SECTION 2> CHOLINERGIC DRUGS ..................................................................................................... 82
CHAPTER 16: MUSCARINIC AGONISTS .................................................................................................... 82
CHAPTER 17: MUSCARINIC ANTAGONISTS ............................................................................................. 86
CHAPTER 18: CHOLINESTERASE INHIBITORS AND THEIR USE IN MYASTHENIA GRAVIS ........................ 90
CHAPTER 19: DRUGS THAT BLOCK NICOTINIC CHOLINERGIC TRANSMISSION ....................................... 95
SECTION 3> ADRENERGIC DRUGS ..................................................................................................... 100
CHAPTER 20: ADRENERGIC AGONISTS .................................................................................................. 100
CHAPTER 21: ADRENERGIC ANTAGONISTS ........................................................................................... 106
CHAPTER 22: INDIRECT-ACTING ANTIADRENERGIC AGENTS ................................................................ 113
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ........................................................................................... 119
SECTION 4>INTRODUCTION .............................................................................................................. 119
CHAPTER 23: INTRODUCTION TO CENTRAL NERVOUS SYSTEM PHARMACOLOGY .............................. 119
, SECTION 5> DRUGS FOR NEURODEGENERATIVE DISORDERS .......................................................... 123
CHAPTER 24: DRUGS FOR PARKINSON DISEASE ................................................................................... 123
CHAPTER 25: DRUGS FOR ALZHEIMER DISEASE.................................................................................... 130
CHAPTER 26: DRUGS FOR MULTIPLE SCLEROSIS .................................................................................. 136
SECTION 6> NEUROLOGIC DRUGS .................................................................................................... 142
CHAPTER 27: DRUGS FOR SEIZURE DISORDERS .................................................................................... 142
CHAPTER 28: DRUGS FOR MUSCLE SPASM AND SPASTICITY................................................................ 151
SECTION 7>DRUGS FOR PAIN............................................................................................................ 156
CHAPTER 29: LOCAL ANESTHETICS ....................................................................................................... 156
CHAPTER 30: GENERAL ANESTHETICS................................................................................................... 162
CHAPTER 31: OPIOID ANALGESICS, OPIOID ANTAGONISTS, AND NONOPIOID CENTRALLY ACTING
ANALGESICS .......................................................................................................................................... 169
CHAPTER 32: PAIN MANAGEMENT IN PATIENTS WITH CANCER .......................................................... 176
CHAPTER 33: DRUGS FOR HEADACHE .................................................................................................. 185
SECTION 8> PHYSIOTHERAPEUTIC DRUGS ........................................................................................ 192
CHAPTER 34: ANTIPSYCHOTIC AGENTS AND THEIR USE IN SCHIZOPHRENIA ....................................... 192
CHAPTER 35: ANTIDEPRESSANTS .......................................................................................................... 199
CHAPTER 36: DRUGS FOR BIPOLAR DISORDER ..................................................................................... 208
CHAPTER 37: SEDATIVE-HYPNOTIC DRUGS .......................................................................................... 214
CHAPTER 38: MANAGEMENT OF ANXIETY DISORDERS ........................................................................ 222
CHAPTER 39: CENTRAL NERVOUS SYSTEM STIMULANTS AND ATTENTION-DEFICIT/HYPERACTIVITY
DISORDER .............................................................................................................................................. 227
SECTION 9>SUBSTANCE USE DISORDERS.......................................................................................... 232
CHAPTER 40: SUBSTANCE USE DISORDERS I: BASIC CONSIDERATIONS ............................................... 232
CHAPTER 41: SUBSTANCE USE DISORDERS II: ALCOHOL ...................................................................... 237
CHAPTER 42: SUBSTANCE USE DISORDERS III: NICOTINE ..................................................................... 246
CHAPTER 43: SUBSTANCE USE DISORDERS IV: MAJOR DRUGS OF ABUSE OTHER THAN ALCOHOL AND
NICOTINE............................................................................................................................................... 251
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECROLYTE BALANCE ........................................................... 259
CHAPTER 44: DIURETICS ....................................................................................................................... 259
CHAPTER 45: AGENTS AFFECTING THE VOLUME AND ION CONTENT OF BODY FLUIDS ...................... 265
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS AND BLOOD .............................................. 271
CHAPTER 46: REVIEW OF HEMODYNAMICS ......................................................................................... 271
CHAPTER 47: DRUGS ACTING ON THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM ........................ 275
, CHAPTER 48: CALCIUM CHANNEL BLOCKERS ....................................................................................... 281
CHAPTER 49: VASODILATORS ............................................................................................................... 284
CHAPTER 50: DRUGS FOR HYPERTENSION ........................................................................................... 289
CHAPTER 51: DRUGS FOR HEART FAILURE ........................................................................................... 299
CHAPTER 52: ANTIDYSRHYTHMIC DRUGS ............................................................................................ 308
CHAPTER 53: DRUGS THAT HELP NORMALIZE CHOLESTEROL AND TRIGLYCERIDE LEVELS .................. 318
CHAPTER 54: DRUGS FOR ANGINA PECTORIS....................................................................................... 327
CHAPTER 55: ANTICOAGULANT, ANTIPLATELET, AND THROMBOLYTIC DRUGS .................................. 336
CHAPTER 56: MANAGEMENT OF ST-ELEVATION MYOCARDIAL INFARCTION ...................................... 344
CHAPTER 57: DRUGS FOR HEMOPHILIA................................................................................................ 350
CHAPTER 58: DRUGS FOR DEFICIENCY ANEMIAS ................................................................................. 356
CHAPTER 59: HEMATOPOIETIC AGENTS ............................................................................................... 363
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ....................................................................................... 369
CHAPTER 60: DRUGS FOR DIABETES MELLITUS .................................................................................... 369
CHAPTER 61: DRUGS FOR THYROID DISORDERS................................................................................... 377
CHAPTER 62: DRUGS RELATED TO HYPOTHALAMIC AND PITUITARY FUNCTION ................................. 384
CHAPTER 63: DRUGS FOR DISORDERS OF THE ADRENAL CORTEX ....................................................... 390
UNIT IX: WOMEN’S HEALTH ...................................................................................................................... 395
CHAPTER 64: ESTROGENS AND PROGESTINS: BASIC PHARMACOLOGY AND NONCONTRACEPTIVE
APPLICATIONS ....................................................................................................................................... 395
CHAPTER 65: BIRTH CONTROL .............................................................................................................. 400
CHAPTER 66: DRUG THERAPY FOR INFERTILITY.................................................................................... 408
CHAPTER 67: DRUGS THAT AFFECT UTERINE FUNCTION ..................................................................... 414
UNIT X: MEN’S HEALTH ............................................................................................................................. 420
CHAPTER 68: ANDROGENS ................................................................................................................... 420
CHAPTER 69: DRUGS FOR ERECTILE DYSFUNCTION AND BENIGN PROSTATIC HYPERPLASIA .............. 426
UNIT XI: ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOLOGIC DRUGS ......................................... 431
CHAPTER 70: REVIEW OF THE IMMUNE SYSTEM ................................................................................. 431
CHAPTER 71: CHILDHOOD IMMUNIZATION ......................................................................................... 436
CHAPTER 72: IMMUNOSUPPRESSANTS ................................................................................................ 444
CHAPTER 73: ANTIHISTAMINES ............................................................................................................ 449
CHAPTER 74: CYCLOOXYGENASE INHIBITORS, NONSTEROIDAL ANTI-INFLAMMATORY DRUGS AND
ACETAMINOPHEN ................................................................................................................................. 456
CHAPTER 75: GLUCOCORTICOIDS IN NONENDOCRINE DISORDERS ..................................................... 463
/QUESTION AND ANSWERS WELL EXPLAINED. Author: Jacqueline Burchum| Laura
,TABLE OF CONTENTS
UNIT I: INTRODUCTION ................................................................................................................................. 6
CHAPTER 01: ORIENTATION TO PHARMACOLOGY ................................................................................... 6
CHAPTER 02: APPLICATION OF PHARMACOLOGY IN NURSING PRACTICE ............................................... 8
CHAPTER 03: DRUG REGULATION, DEVELOPMENT, NAMES, AND INFORMATION................................ 16
UNIT II: BASIC PRINCIPLES OF PHAMACOLOGY .......................................................................................... 19
CHAPTER 04: PHARMACOKINETICS......................................................................................................... 19
CHAPTER 05: PHARMACODYNAMICS ..................................................................................................... 26
CHAPTER 06: DRUG INTERACTIONS ........................................................................................................ 30
CHAPTER 07: ADVERSE DRUG REACTIONS AND MEDICATION ERRORS ................................................. 37
CHAPTER 08: INDIVIDUAL VARIATION TO DRUG RESPONSES ................................................................ 43
CHAPTER 09: GENETIC AND GENOMIC CONSIDERATIONS ..................................................................... 49
CHAPTER 10: INTRODUCTION TO IMMUNOMODULATORS ................................................................... 53
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ....................................................................................... 57
CHAPTER 11: DRUG THERAPY DURING PREGNANCY AND BREAST-FEEDING ......................................... 57
CHAPTER 12: DRUG THERAPY IN PEDIATRIC PATIENTS .......................................................................... 62
CHAPTER 13: DRUG THERAPY IN OLDER ADULTS ................................................................................... 67
UNIT IV: PERIPHERALNERVOUS SYSTEM DRUGS ........................................................................................ 74
SECTION 1> INTRODUCTION ............................................................................................................... 74
CHAPTER 14: BASIC PRINCIPLES OF NEUROPHARMACOLOGY ............................................................... 74
CHAPTER 15: PHYSIOLOGY OF THE PERIPHERAL NERVOUS SYSTEM ...................................................... 78
SECTION 2> CHOLINERGIC DRUGS ..................................................................................................... 82
CHAPTER 16: MUSCARINIC AGONISTS .................................................................................................... 82
CHAPTER 17: MUSCARINIC ANTAGONISTS ............................................................................................. 86
CHAPTER 18: CHOLINESTERASE INHIBITORS AND THEIR USE IN MYASTHENIA GRAVIS ........................ 90
CHAPTER 19: DRUGS THAT BLOCK NICOTINIC CHOLINERGIC TRANSMISSION ....................................... 95
SECTION 3> ADRENERGIC DRUGS ..................................................................................................... 100
CHAPTER 20: ADRENERGIC AGONISTS .................................................................................................. 100
CHAPTER 21: ADRENERGIC ANTAGONISTS ........................................................................................... 106
CHAPTER 22: INDIRECT-ACTING ANTIADRENERGIC AGENTS ................................................................ 113
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ........................................................................................... 119
SECTION 4>INTRODUCTION .............................................................................................................. 119
CHAPTER 23: INTRODUCTION TO CENTRAL NERVOUS SYSTEM PHARMACOLOGY .............................. 119
, SECTION 5> DRUGS FOR NEURODEGENERATIVE DISORDERS .......................................................... 123
CHAPTER 24: DRUGS FOR PARKINSON DISEASE ................................................................................... 123
CHAPTER 25: DRUGS FOR ALZHEIMER DISEASE.................................................................................... 130
CHAPTER 26: DRUGS FOR MULTIPLE SCLEROSIS .................................................................................. 136
SECTION 6> NEUROLOGIC DRUGS .................................................................................................... 142
CHAPTER 27: DRUGS FOR SEIZURE DISORDERS .................................................................................... 142
CHAPTER 28: DRUGS FOR MUSCLE SPASM AND SPASTICITY................................................................ 151
SECTION 7>DRUGS FOR PAIN............................................................................................................ 156
CHAPTER 29: LOCAL ANESTHETICS ....................................................................................................... 156
CHAPTER 30: GENERAL ANESTHETICS................................................................................................... 162
CHAPTER 31: OPIOID ANALGESICS, OPIOID ANTAGONISTS, AND NONOPIOID CENTRALLY ACTING
ANALGESICS .......................................................................................................................................... 169
CHAPTER 32: PAIN MANAGEMENT IN PATIENTS WITH CANCER .......................................................... 176
CHAPTER 33: DRUGS FOR HEADACHE .................................................................................................. 185
SECTION 8> PHYSIOTHERAPEUTIC DRUGS ........................................................................................ 192
CHAPTER 34: ANTIPSYCHOTIC AGENTS AND THEIR USE IN SCHIZOPHRENIA ....................................... 192
CHAPTER 35: ANTIDEPRESSANTS .......................................................................................................... 199
CHAPTER 36: DRUGS FOR BIPOLAR DISORDER ..................................................................................... 208
CHAPTER 37: SEDATIVE-HYPNOTIC DRUGS .......................................................................................... 214
CHAPTER 38: MANAGEMENT OF ANXIETY DISORDERS ........................................................................ 222
CHAPTER 39: CENTRAL NERVOUS SYSTEM STIMULANTS AND ATTENTION-DEFICIT/HYPERACTIVITY
DISORDER .............................................................................................................................................. 227
SECTION 9>SUBSTANCE USE DISORDERS.......................................................................................... 232
CHAPTER 40: SUBSTANCE USE DISORDERS I: BASIC CONSIDERATIONS ............................................... 232
CHAPTER 41: SUBSTANCE USE DISORDERS II: ALCOHOL ...................................................................... 237
CHAPTER 42: SUBSTANCE USE DISORDERS III: NICOTINE ..................................................................... 246
CHAPTER 43: SUBSTANCE USE DISORDERS IV: MAJOR DRUGS OF ABUSE OTHER THAN ALCOHOL AND
NICOTINE............................................................................................................................................... 251
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECROLYTE BALANCE ........................................................... 259
CHAPTER 44: DIURETICS ....................................................................................................................... 259
CHAPTER 45: AGENTS AFFECTING THE VOLUME AND ION CONTENT OF BODY FLUIDS ...................... 265
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS AND BLOOD .............................................. 271
CHAPTER 46: REVIEW OF HEMODYNAMICS ......................................................................................... 271
CHAPTER 47: DRUGS ACTING ON THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM ........................ 275
, CHAPTER 48: CALCIUM CHANNEL BLOCKERS ....................................................................................... 281
CHAPTER 49: VASODILATORS ............................................................................................................... 284
CHAPTER 50: DRUGS FOR HYPERTENSION ........................................................................................... 289
CHAPTER 51: DRUGS FOR HEART FAILURE ........................................................................................... 299
CHAPTER 52: ANTIDYSRHYTHMIC DRUGS ............................................................................................ 308
CHAPTER 53: DRUGS THAT HELP NORMALIZE CHOLESTEROL AND TRIGLYCERIDE LEVELS .................. 318
CHAPTER 54: DRUGS FOR ANGINA PECTORIS....................................................................................... 327
CHAPTER 55: ANTICOAGULANT, ANTIPLATELET, AND THROMBOLYTIC DRUGS .................................. 336
CHAPTER 56: MANAGEMENT OF ST-ELEVATION MYOCARDIAL INFARCTION ...................................... 344
CHAPTER 57: DRUGS FOR HEMOPHILIA................................................................................................ 350
CHAPTER 58: DRUGS FOR DEFICIENCY ANEMIAS ................................................................................. 356
CHAPTER 59: HEMATOPOIETIC AGENTS ............................................................................................... 363
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS ....................................................................................... 369
CHAPTER 60: DRUGS FOR DIABETES MELLITUS .................................................................................... 369
CHAPTER 61: DRUGS FOR THYROID DISORDERS................................................................................... 377
CHAPTER 62: DRUGS RELATED TO HYPOTHALAMIC AND PITUITARY FUNCTION ................................. 384
CHAPTER 63: DRUGS FOR DISORDERS OF THE ADRENAL CORTEX ....................................................... 390
UNIT IX: WOMEN’S HEALTH ...................................................................................................................... 395
CHAPTER 64: ESTROGENS AND PROGESTINS: BASIC PHARMACOLOGY AND NONCONTRACEPTIVE
APPLICATIONS ....................................................................................................................................... 395
CHAPTER 65: BIRTH CONTROL .............................................................................................................. 400
CHAPTER 66: DRUG THERAPY FOR INFERTILITY.................................................................................... 408
CHAPTER 67: DRUGS THAT AFFECT UTERINE FUNCTION ..................................................................... 414
UNIT X: MEN’S HEALTH ............................................................................................................................. 420
CHAPTER 68: ANDROGENS ................................................................................................................... 420
CHAPTER 69: DRUGS FOR ERECTILE DYSFUNCTION AND BENIGN PROSTATIC HYPERPLASIA .............. 426
UNIT XI: ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOLOGIC DRUGS ......................................... 431
CHAPTER 70: REVIEW OF THE IMMUNE SYSTEM ................................................................................. 431
CHAPTER 71: CHILDHOOD IMMUNIZATION ......................................................................................... 436
CHAPTER 72: IMMUNOSUPPRESSANTS ................................................................................................ 444
CHAPTER 73: ANTIHISTAMINES ............................................................................................................ 449
CHAPTER 74: CYCLOOXYGENASE INHIBITORS, NONSTEROIDAL ANTI-INFLAMMATORY DRUGS AND
ACETAMINOPHEN ................................................................................................................................. 456
CHAPTER 75: GLUCOCORTICOIDS IN NONENDOCRINE DISORDERS ..................................................... 463
