0313202 Questions and Answers 2025
WhatAisAtheAlactationAriskAforAVibrid?A-ACORRECTAANSWERSA-currentlyAunknown.
WhatAwarningAdoAallAanti-depressantsAcarry?A-ACORRECTAANSWERSA-
BlackAboxAwarningAaboutAsuicide
DescribeAanAappropriateAFluoxetineAtaper?A-ACORRECTAANSWERSA-
AAtaperAforAFluoxatine/AProzacAisAnotAneededAdueAtoAitsAlongAhalf-
lifeA(upAtoA144Ahours).AItAtakesAaboutA5AweeksAtoAachieveAsteadyAstateAandAwillAself-taper
WhatAisASerotoninASyndrome?A-ACORRECTAANSWERSA-
ToxicAlevelsAofAserotonin.ACanAbeAdueAtoAdosesAofASSRIsA(includingAattemptedAoverdoses
),AinteractionsAbetweenASSRIsAandAMAOIsAorASSRIsAandATramadol
ListASerotoninAsyndromeAsymptoms?A-ACORRECTAANSWERSA-
TheseAsymptomsAoverlapAwithANeurolepticAMalignantASyndrome:AElevationsAin:ABloodAPr
essure,APulse,ATemp,AmuscleArigidity,Adrooling,Asweating.
TheseAsymptomsAareAdistinctAtoASerotoninASyndrome:Aclonus,AagitatedAconfusion,AhyperA
reflexiaA&AbowelAsounds;Adiarrhea
DescribeANeonatalAeffectsAofAantidepressants?A-ACORRECTAANSWERSA-
ifAMomAisAonAanASSRIAbabyAwillAhaveA'discontinuationAsyndrome'Acrankiness,AirritabilityAfor
AupAtoAaAfewAdays
WhatAareAlactationAriskAcategories?A-ACORRECTAANSWERSA-
L1,Asafest;AL2,Asafer;AL3,AmoderatelyAsafe;AL4,ApossiblyAhazardousAthereAisApositiveAevide
nceAofArisk;AL5,AcontraindicatedA-AsignificantAdocumentedArisk.
AreAthereAanyAdrugsAinAtheAL1Acategory?A-ACORRECTAANSWERSA-
AcetaminophenA('causeAeveryoneAcanAtakeAtylenol),AsomeAofAtheApenicillinA(moldyAbread;A
grossAbutArelativelyAsafe),Adepo-proveraA(injectableAorAimplantableABCAonly)
WhatApsychiatricAdrugsAareAL4A-ACORRECTAANSWERSA-
LithiumA(crossesAbreastAmilk),AsomeAofAtheAolderAantipsychoticsA(soAjustAthinkA'useASGAsAi
nAlactation')
AreAanyAdrugsAinAtheAL5Acategory?A-ACORRECTAANSWERSA-
Ziprasadone/AGeodonA(someAquestionAofAitAbeingAL4),ADoxepineA/SinequanA(TCA)AandAco
caine.
FetalAexposureAtoALithiumAasAbeenAassociatedAwithAwhatAbirthAdefects?A-
ACORRECTAANSWERSA-1-polyhydramniosAwhichAisAexcessiveAamnioticAfluid;
2-reversibleAchangesAinAthyroidAfunction;A
3-fetalAandAneonatalAcardiacAarrhythmias;A
4-hypoglycemia;
5-nephrogenicAdiabetesAinsipidus;A
6-prematureAdelivery;AandA
7-floppyAinfantAsyndromeAsimilarAtoAthatAseenAwithAbenzodiazepineAexposure
ListAsymptomsAofAneonatalALithiumAtoxicityA-ACORRECTAANSWERSA-1-flaccidity,A2-
lethargy,AandA3-poorAsuckAreflexes,AwhichAmayApersistAforAmoreAthanA7Adays.
,WhatAareAtheAriskAcategoriesAfromAdrugsAuseAinApregnancyA-ACORRECTAANSWERSA-A-
controlledAstudiesAshowAnoArisk,AB-noAevidenceAofAriskAinAhumans;AC-
riskAcannotAbeAruledAout;AD-positiveAevidenceAofArisk;AX-contraindicatedAinApregnancy.
ListAsomeASSRIsA-ACORRECTAANSWERSA-
Citalopram/Acelexa,AEscitalopram/Alexapro,AParoxetine/Apaxil,ASertraline/Azoloft,AFluoxetin
e/Aprozac,AFluvoxamine/Aluvox.
WhatASSRIsAwouldAyouAconsiderAfirstAforAanAelderlyApatientAandAwhy?A-
ACORRECTAANSWERSA-
Escitalopram/AlexaproAandASertraline/AzoloftAbecauseAofAminimalAcytochromeAP450A2D6Ai
nhibition.
ListAtheAmoreAcommonASSRIAsideAeffectsA-ACORRECTAANSWERSA-
Agitation;AbowelAchanges;AHA;Afatigue;ANausea.AThenAlongerAterm:AsexualAdysfunctionAin
cludingAdelayedAorAnoAorgasm,AerectileAdysfunctionA(usuallyAchronic;AupAtoA75%AandApeop
leAwillAtendAnotAtoAmentionAit)A[thereAisAoff-labelAuseAofASSRIsAforAprematureAejaculation].
WhatAareAtheAmaxAdosesAofAcitalopram/celexaA-ACORRECTAANSWERSA-
upAtoA40AmgAorA20AmgAinA>60AyoA(dueAtoAQTAprolongation)
WhatASSRIsAareAL2?A-ACORRECTAANSWERSA-
ThinkA"Likely/safeALaterAinAtheAalphabet"AorA"Sorry,AgoAtoAtheAendAofAtheAline/Aalphabet":AP
aroxetine/ApaxilA(isAaADAinApregnancy);ASertraline/Azoloft;AandAtrazadone/Adesyrel
ListAsomeASNRIsA-ACORRECTAANSWERSA-
Think:ASNRIAsnarkyAandAmean/ineAifAnotAonAtime;AVenlafaxine/effexor,ADuloxetine/cymbal
ta,ADesvenlafaxine/Pristiq
SNRIAsideAeffectsA-ACORRECTAANSWERSA-UsuallyAtransient:
agitation;
bowelAchanges;A
dizziness;A
dryAmouth;A
fatigue;A
Nausea;
sexualAsideAeffectsA(canAbeAchronic),AelevatedAbloodApressureA(mayArequireAmonitoringAifA
peopleAareAonABPAmeds);A
WithAdoseAincreases,AnauseaAisAtheAmostAcommonAsideAeffect.
WhatAisAtheAscoringAofAtheABECKAdepressionAinventory?A-ACORRECTAANSWERSA-0-
13AminimalAdepression;A
14-19AisAmild;
20-28AisAmoderate;A
29-63AisAsevereAdepression
26AyoAwithA2yoAdaughterAreportsAdepressionAstartingAafterAtheAchild'sAbirth.ABeckADepressi
onAInventoryABDIAscoreAofA23.AHealthyA&A16AwApregnant.AWhichAwouldAbeAinappropriate?A
A-noAmedsAorApsychotherapyAnow,AB-WeeklyAinterpersonalAtherapy,AC-
InitiateAcitalopram/celexa,AD-InitiateAsertraline/zoloftA-ACORRECTAANSWERSA-
InappropriateAwouldAbeAA-noAmedsAorApsychotherapy.
WhatApregnancyAcategoryAisAaAdrugAthatAhasAbeenAdemonstratedAtoAcauseAteratogenicAeff
ects,AbutAbenefitsAusuallyAoutweighAriskA*inAaAlifeAthreateningAsituation*A-
ACORRECTAANSWERSA-D.A
,AnAexampleAwouldAbeALithiumA(fetalAheartAissues),AvalproicAacidA(fetalAneuralAtubeAissues)
AandAmostAbenzosA(caution;AasAsomeAbenzosAareAXAsoAcheck).
IsAECTAsafeAinApregnancy?A-ACORRECTAANSWERSA-yes
ThereAisApositiveAevidenceAthatALithiumAuseAwhileAbreastfeedingAcanAposeAriskAtoAinfant;At
hisAmakesAitAwhatAlactationAcategory?A-ACORRECTAANSWERSA-L4
OverdoseAofAwhatAcategoryAofAmedicationsAwouldAbeAmostAlikelyAtoAbeAfatal:ATricyclicAanti
depressants,ASSRIs,ASNRIs?A-ACORRECTAANSWERSA-
TricyclicAantidepressants;AoftenAtheyAwereAonlyAdispensedAinAweekAorAtwoAweekAamounts.
WhatAdrugAclassAisAsertraline?A-ACORRECTAANSWERSA-Sertraline/zoloftAisAanASSRI
WhatAdrugAclassAisAphenelzine?A-ACORRECTAANSWERSA-Phenelzine/nardilAisAanAMAOI
WhatAdrugAclassAisAselegilineA/Eldepryl?A-ACORRECTAANSWERSA-MAOI
WhatAdrugAclassAisAphenelzineA/Nardil?A-ACORRECTAANSWERSA-MAOI
WhatAdoAMAOAinhibitorsAdo?A-ACORRECTAANSWERSA-
MAOAisAanAenzymeAwhichAmetabolizesAserotonin,AnorepinephrineAandAdopamine.AByAinhi
bitingAthis,AMAOIsAincreaseAlevelsAofAthoseAneurotransmitters.
IsAthereAaA"lessAdangerous"AMAOI?A-ACORRECTAANSWERSA-
Yes.AReversibleAinhibitorsAofAmonoamineAoxidaseAtypeAAA(RIMAs)AareAdistinguishedAfrom
AtheAolderAMAOIsAbyAtheirAselectivityAandAreversibility.ADietaryArestrictionsAareAnotArequire
dAduringARIMAAtherapy,AhypertensiveAcrisesAareAquiteArare.AMoclobemideA/AAurorexA[unav
ailableAinAtheAUS],AandABrofaromine/AConsonar.
WhatAdoAyouAneverAuseAanAMAOIAwith?A-ACORRECTAANSWERSA-
AnythingAthatAblocksAserotoninAre-uptake.AExamples:ASSRIs,
WhatAfoodAinteractionAMUSTAyouAbeAawareAofAwhenAprescribingAanAMAOI?A-
ACORRECTAANSWERSA-
FoodsAhighAinAtyramineAcanAprecipitateAaAcrisis.ASoAagedAmeatsAorAcheeses,Adried,Asmok
ed,AunpasteurizedAbeer,Asaurkraut,AkimAchee.
IsAthereAaAdoseAofAanAMAOIAthatAdoesAnotArequireAdietaryArestrictions?A-
ACORRECTAANSWERSA-
IfAyouAeatAit,AyouAhaveAtoAwatchAyourAeating;AhoweverAifAyourAnotAeating,AthereAisAone:AEM
SAMAisAtheAnameAofAtheAtransdermalAselegilineApatch;AaAdoseAofA6AmgAperA24AhoursAdoesA
notArequireAdietaryAadjustment.
WhatAdrugAclassAisAFluoxetine?A-ACORRECTAANSWERSA-Fluoxetine/prozacAisAanASSRI
WhatAisAaAchantAtoArememberAsymptomsAofAoverdoseAinAopiates?A-
ACORRECTAANSWERSA-CoolAtoAtheAtouch,AunresponsiveAtoApain,
HungerAdiminished,AandAscarsAoverAvein.
PupilsApinpointed,AandAbloodApressureAlow,
UrineAdiminished,AandAbreathingAisAslow
WhatAareAsideAeffectsAofATCAs?A-ACORRECTAANSWERSA-
AnticholinergicAeffects:Aconstipation;Adelirium;AdryAmouth;A
EKGAchanges:A[flattenedATAwaves;AdepressedAS-TAsegments].
orthostaticAhypotension;Asedation;Atachycardia;AurinaryAretention.
WhatAoffAlabelAuseAisAthereAforAWellbutrinA(bupropion)?A-ACORRECTAANSWERSA-
Attention-deficit/hyperactivityAdisorderA(ADHD)
WhatAdrugAcategoryAisAWellbutrin/Abupropion?A-ACORRECTAANSWERSA-
ItAisAaAnorepinephrineAandAdopamineAreuptakeAinhibitor;ANDRI.
, WhatAareAappropriateApsychotherapyAchoicesAforAMajorADepressiveADisorderA(MDD)?A-
ACORRECTAANSWERSA-1-CognitiveABehavioralATherapyA(CBT);A2-
InterpersonalATherapyA(IPT);A3-ProblemAsolvingAtherapy;A4-psychodynamicAtherapy
HowAlongAisAaAsufficientAtrialAofApharmacologicAtreatmentAbeforeAchangingAorAaugmenting
?A-ACORRECTAANSWERSA-4-8Aweeks
IfAthereAisAnoAimprovementAinAyourApatientAinA4-8Aweeks,AwhatAdoAyouAassess?A-
ACORRECTAANSWERSA-AssessAforA1-diagnosisA(isAitAaccurate),A2-
adverseAorAsideAeffects,A3-complicatingAco-occurringAorAco-morbidAconditions,A4-
psychosocialAfactors,A5-qualityAofAtherapeuticAalliance,A6-treatmentAadherence
WhatAisAtheAnormalArangeAofATSH?A-ACORRECTAANSWERSA-0.5AtoA4.5AorA5.0
WhatAareAoptionsAforAtreatment-resistantAdepression?A-ACORRECTAANSWERSA-
ECT,ATranscranialAmagneticAstimulation,AvagusAnerveAstimulation
OnceAaAdepressiveApatientAisAstabilizedA("backAtoA100%"),AhowAlongAdoAyouAkeepAthemAon
AmaintenanceAmedicationAdosages?A-ACORRECTAANSWERSA-
ContinueAantidepressantsA-AorAwhateverAwasAeffectiveA-AforA4-
9Amonths,A&AmonitorAforAsignsAofArelapse.AUseAstandardizedAtests,AscreeningAtoolsAandAifA
possibleAincludeAtheAfamilyAtoAhelpAidentifyAprodromeAsymptomsAsuchAasAoversleeping.
WhatAisAtheAlifetimeAprevalenceAofAMajorADepressiveADisorder?A-
ACORRECTAANSWERSA-
17%,AinitiallyAequalAbetweenAgenders,AafterA13AwomenAgetAitAtwiceAasAoftenAasAmen.
WhatAisAageAofAonsetAforAMajorADepressiveADisorder?A-ACORRECTAANSWERSA-
MeanAageAisA40Ayears,AprevalenceAdecreasesAasAageAincreases.
WhatAisAtheArecurrenceArateAforAMajorADepressiveADisorderA(MDD)?A-
ACORRECTAANSWERSA-20%AwithinA6Amonths;A50-
80%AatAleastAoneArecurrenceAduringAlifetime.
ListAriskAfactorsAforArelapseAforAMajorADepressiveADisorderA(MDD)A-
ACORRECTAANSWERSA-1-PersistantAmildAsymptoms,A2-hxAofAMDD,A3-
earlyAageAofAonset,A*4-
comorbidAchronicAmedicalAorApsychiatricAdisorders*A(eitherAofAtheseAindicatesAmaintenanc
eAtreatment),A5-chronicApsychosocialAstressors,A6-negativeAcopingAstyle,A7-
chronicAsleepAdisorders,A8-familyAhistoryAofApsychiatricAdisorders
ListAriskAfactorsAforAMajorADepressiveADisorderA-ACORRECTAANSWERSA-1-Genetics,A2-
lowAselfAesteem,A3-historyAofAanAepisode,A4-conductAdisorder,A5-trauma,A6-
stressfulAlifeAevents,A7-AparentalAloss,A8-maritalAproblems,A9-
lowAsocioeconomicAstatus,A10-lowAeducationAachievement,A11-
medicalAinpatientsAareAatA15%AhigherArisk,A12-Peri-AandApost-Apartum.
WhatAareArangesAforAtheAZungAself-ratedAanxietyAtool?A-ACORRECTAANSWERSA-20-
44ANormalARange
45-59AMildAtoAModerateAAnxietyALevels
60-74AMarkedAtoASevereAAnxietyALevels
75-80AExtremeAAnxietyALevels
WhatAareArangesAforAtheAZungAself-ratedAdepressionAtool?A-ACORRECTAANSWERSA-20-
44ANormalARange
45-59AMildlyADepressed
60-69AModeratelyADepressed
70AandAaboveASeverelyADepressed