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Breast Cancer Questions with Detailed Verified
Answers (100% Correct Answers) /Already Graded
A+
Approximately 3-5% of all breast cancers are medullary carcinoma. Medullary
carcinomas are most common in patients with the BRCA1 mutations . Which
of the following correctly characterizes medullary carcinomas
a. ER positive, PR positive, Her2 positive
b. ER positive, PR positive, Her2 negative
c. ER positive, PR negative, Her2 negative
d. ER negative, PR negative, Her2 negative
Ans: d. ER negative, PR negative, Her2 negative
True or False: Regarding the choice of surgery, lumpectomy followed by
radiation therapy with breast cancer is equivalent to mastectomy .
Ans: TRUE
There are currently two gene assays that are used in clinical practice to
determine risk of recurrence and aid the decision on adjuvant chemotherapy in
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patients. One of these assays is the Oncotype Dx. What is the name of the
other assay?
Ans: MammaPrint
Select the three most validated markers for breast cancer
a. Estrogen Receptor
b. Progesterone Receptor
c. Her2/ErB2
d. Testosterone Receptor
Ans: a. Estrogen Receptor
b. Progesterone Receptor
c. Her2/ErB2
25% of all cases of breast cancer are Her2/Erb2 positive only. This form of
breast cancer is highly progressive, giving these patients a poorer prognosis.
What chemotherapeutic agent is used to treat Her2/Erb2?
a. Trastuzumab (Herceptin)
b. Tamoxifen (Nolvadex)
c. Raloxifene (Evista)
© Get it right 2025 Getaway - Stuvia US All rights reserved
Breast Cancer Questions with Detailed Verified
Answers (100% Correct Answers) /Already Graded
A+
Approximately 3-5% of all breast cancers are medullary carcinoma. Medullary
carcinomas are most common in patients with the BRCA1 mutations . Which
of the following correctly characterizes medullary carcinomas
a. ER positive, PR positive, Her2 positive
b. ER positive, PR positive, Her2 negative
c. ER positive, PR negative, Her2 negative
d. ER negative, PR negative, Her2 negative
Ans: d. ER negative, PR negative, Her2 negative
True or False: Regarding the choice of surgery, lumpectomy followed by
radiation therapy with breast cancer is equivalent to mastectomy .
Ans: TRUE
There are currently two gene assays that are used in clinical practice to
determine risk of recurrence and aid the decision on adjuvant chemotherapy in
© Get it right 2025 Getaway - Stuvia US All rights reserved
, Click here for more: Scholars nexus
patients. One of these assays is the Oncotype Dx. What is the name of the
other assay?
Ans: MammaPrint
Select the three most validated markers for breast cancer
a. Estrogen Receptor
b. Progesterone Receptor
c. Her2/ErB2
d. Testosterone Receptor
Ans: a. Estrogen Receptor
b. Progesterone Receptor
c. Her2/ErB2
25% of all cases of breast cancer are Her2/Erb2 positive only. This form of
breast cancer is highly progressive, giving these patients a poorer prognosis.
What chemotherapeutic agent is used to treat Her2/Erb2?
a. Trastuzumab (Herceptin)
b. Tamoxifen (Nolvadex)
c. Raloxifene (Evista)
© Get it right 2025 Getaway - Stuvia US All rights reserved
