PEPTIC ULCER DISEASE PRACTICE
QUESTIONS WITH CORRECT
ANSWERS UPDATED 2025
A client with peptic ulcer disease (PUD) asks why stomach pain occurs 2 to 3 hours
after eating. Which response should the nurse make to this client?
A."The pain occurs when your stomach is empty."
B."The food that you ate for dinner likely contained too much fat, causing pain."
C."The acid in your stomach is increased at night, causing pain."
D."The food in your stomach takes longer to digest at night, which causes pain." -
✔✔A."The pain occurs when your stomach is empty."
Pain from PUD occurs when the stomach is empty, typically 2dash3 hours after a
meal. The other responses are incorrect.
The nurse is reviewing the complications of peptic ulcer disease (PUD) with a group
of new staff nurses. Which statement regarding peritonitis should the nurse include
in the teaching?
A.
"Peritonitis occurs due to the obstruction of the pyloric region of the stomach and
duodenum. The increased pressure from the obstruction leads to peritonitis."
B."Peritonitis occurs when the ulcer penetrates through the mucosal wall, causing
gastric or duodenal contents to enter the peritoneum."
COPYRIGHT © 2025 BY EMILLY CHARLOTTE, ALL RIGHTS RESERVED 1
,C."Chemical peritonitis occurs between 6 and 12 hours after perforation, when the
acids from the stomach or duodenum create an inflammatory response."
D."Bacterial peritonitis happens immediately after perforation as bacteria proliferate
in the peritoneal cavity." - ✔✔B."Peritonitis occurs when the ulcer penetrates
through the mucosal wall, causing gastric or duodenal contents to enter the
peritoneum."
Peritonitis occurs due to the ulcer penetrating through the mucosal wall, causing
gastric or duodenal contents to enter the peritoneum. Chemical peritonitis is
immediate after perforation. Bacterial peritonitis occurs between 6 and 12 hours after
perforation. Gastric outlet obstruction, not perforation, occurs due to the obstruction
of the pyloric region of the stomach and duodenum.
The nurse is reviewing risk factors for peptic ulcer disease (PUD) with a group of
community members. Which factor should the nurse include in the presentation?
(Select all that apply.)
A.Chronic alcohol abuse
B.Cigarette smoking
C.Unsanitary living conditions
D.Chronic H. pylori infection
E.Chronic use of NSAIDs - ✔✔B,C,D,E
B.Cigarette smoking
C.Unsanitary living conditions
D.Chronic H. pylori infection
E.Chronic use of NSAIDs
COPYRIGHT © 2025 BY EMILLY CHARLOTTE, ALL RIGHTS RESERVED 2
, Cigarette smoking, chronic use of NSAIDs, chronic H. pylori infection, and
unsanitary living conditions are all risk factors for PUD. Chronic alcohol abuse is not
considered a risk factor for PUD.
Which pathophysiologic change contributing to the development of peptic ulcer
disease occurs secondary to H. pylori infection? (Select all that apply.)
A.The inflammatory response to H. pylori contributes to epithelial cell damage
without producing immunity.
B.Prostaglandin synthesis is interrupted, which impacts the ability to maintain the
gastric mucosal barrier.
C.Production of protective bicarbonate by the epithelial cells is inhibited.
D.Enzymes are produced that reduce the efficacy of the mucous gel, which protects
the gastric mucosa.
E.Topical injury occurs due to H. pylori crossing the lipid membranes of gastric
epithelial cells. - ✔✔A,D
A.The inflammatory response to H. pylori contributes to epithelial cell damage
without producing immunity.
D.Enzymes are produced that reduce the efficacy of the mucous gel, which protects
the gastric mucosa.
The H. pylori bacteria produce enzymes that reduce the efficacy of mucous gel in
protecting the gastric mucosa. Also, the host's inflammatory response to H. pylori
contributes to gastric epithelial cell damage without producing immunity to the
infection. It does not inhibit production of bicarbonate. NSAID use, not H. pylori,
causes topical injury and interrupts prostaglandin synthesis.
The nurse is reviewing assessment data for a client hospitalized with peptic ulcer
disease (PUD). Which assessment information should indicate to the nurse that the
client may be experiencing an obstruction secondary to the ulcer? (Select all that
apply.)
COPYRIGHT © 2025 BY EMILLY CHARLOTTE, ALL RIGHTS RESERVED 3
QUESTIONS WITH CORRECT
ANSWERS UPDATED 2025
A client with peptic ulcer disease (PUD) asks why stomach pain occurs 2 to 3 hours
after eating. Which response should the nurse make to this client?
A."The pain occurs when your stomach is empty."
B."The food that you ate for dinner likely contained too much fat, causing pain."
C."The acid in your stomach is increased at night, causing pain."
D."The food in your stomach takes longer to digest at night, which causes pain." -
✔✔A."The pain occurs when your stomach is empty."
Pain from PUD occurs when the stomach is empty, typically 2dash3 hours after a
meal. The other responses are incorrect.
The nurse is reviewing the complications of peptic ulcer disease (PUD) with a group
of new staff nurses. Which statement regarding peritonitis should the nurse include
in the teaching?
A.
"Peritonitis occurs due to the obstruction of the pyloric region of the stomach and
duodenum. The increased pressure from the obstruction leads to peritonitis."
B."Peritonitis occurs when the ulcer penetrates through the mucosal wall, causing
gastric or duodenal contents to enter the peritoneum."
COPYRIGHT © 2025 BY EMILLY CHARLOTTE, ALL RIGHTS RESERVED 1
,C."Chemical peritonitis occurs between 6 and 12 hours after perforation, when the
acids from the stomach or duodenum create an inflammatory response."
D."Bacterial peritonitis happens immediately after perforation as bacteria proliferate
in the peritoneal cavity." - ✔✔B."Peritonitis occurs when the ulcer penetrates
through the mucosal wall, causing gastric or duodenal contents to enter the
peritoneum."
Peritonitis occurs due to the ulcer penetrating through the mucosal wall, causing
gastric or duodenal contents to enter the peritoneum. Chemical peritonitis is
immediate after perforation. Bacterial peritonitis occurs between 6 and 12 hours after
perforation. Gastric outlet obstruction, not perforation, occurs due to the obstruction
of the pyloric region of the stomach and duodenum.
The nurse is reviewing risk factors for peptic ulcer disease (PUD) with a group of
community members. Which factor should the nurse include in the presentation?
(Select all that apply.)
A.Chronic alcohol abuse
B.Cigarette smoking
C.Unsanitary living conditions
D.Chronic H. pylori infection
E.Chronic use of NSAIDs - ✔✔B,C,D,E
B.Cigarette smoking
C.Unsanitary living conditions
D.Chronic H. pylori infection
E.Chronic use of NSAIDs
COPYRIGHT © 2025 BY EMILLY CHARLOTTE, ALL RIGHTS RESERVED 2
, Cigarette smoking, chronic use of NSAIDs, chronic H. pylori infection, and
unsanitary living conditions are all risk factors for PUD. Chronic alcohol abuse is not
considered a risk factor for PUD.
Which pathophysiologic change contributing to the development of peptic ulcer
disease occurs secondary to H. pylori infection? (Select all that apply.)
A.The inflammatory response to H. pylori contributes to epithelial cell damage
without producing immunity.
B.Prostaglandin synthesis is interrupted, which impacts the ability to maintain the
gastric mucosal barrier.
C.Production of protective bicarbonate by the epithelial cells is inhibited.
D.Enzymes are produced that reduce the efficacy of the mucous gel, which protects
the gastric mucosa.
E.Topical injury occurs due to H. pylori crossing the lipid membranes of gastric
epithelial cells. - ✔✔A,D
A.The inflammatory response to H. pylori contributes to epithelial cell damage
without producing immunity.
D.Enzymes are produced that reduce the efficacy of the mucous gel, which protects
the gastric mucosa.
The H. pylori bacteria produce enzymes that reduce the efficacy of mucous gel in
protecting the gastric mucosa. Also, the host's inflammatory response to H. pylori
contributes to gastric epithelial cell damage without producing immunity to the
infection. It does not inhibit production of bicarbonate. NSAID use, not H. pylori,
causes topical injury and interrupts prostaglandin synthesis.
The nurse is reviewing assessment data for a client hospitalized with peptic ulcer
disease (PUD). Which assessment information should indicate to the nurse that the
client may be experiencing an obstruction secondary to the ulcer? (Select all that
apply.)
COPYRIGHT © 2025 BY EMILLY CHARLOTTE, ALL RIGHTS RESERVED 3
