KATZUNG'S BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION TEST BANK, (2024)
BY TODD W. VANDERAH
ALL CHAPTERS 1-67| 10 SECTIONS| LATEST VERSION WITH ALL DETAILED ANSWERS| GRADE A+
16th edition
,section i: basic principles _______________________________________________________ 5
chapter 1: introduction: the nature of drugs & drug development & regulation _________________________ 5
chapter 2: drug receptors & pharmacodynamics _________________________________________________ 23
chapter 3: pharmacokinetics & pharmacodynamics: rational dosing & the time course of drug action _____ 43
chapter 4: drug biotransformation _____________________________________________________________ 57
chapter 5: pharmacogenomics ________________________________________________________________ 71
section ii: autonomic drugs ____________________________________________________ 80
chapter 6. Introduction to autonomic pharmacology ______________________________________________ 80
chapter 7: cholinoceptor-activating & cholinesterase-inhibiting drugs _______________________________ 100
chapter 8: cholinoceptor-blocking drugs _______________________________________________________ 118
chapter 9: adrenoceptor agonists & sympathomimetic drugs ______________________________________ 136
chapter 10: adrenoceptor antagonist drugs _____________________________________________________ 154
section iii: cardiovascular-renal drugs ___________________________________________ 172
chapter 11: antihypertensive agents __________________________________________________________ 172
chapter 12: vasodilators & the treatment of angina pectoris_______________________________________ 192
chapter 13: drugs used in heart failure ________________________________________________________ 209
chapter 14: agents used in cardiac arrhythmias _________________________________________________ 226
chapter 15: diuretic agents __________________________________________________________________ 244
section iv: drugs with important actions on smooth muscle _________________________ 261
chapter 16: histamine, serotonin, & the ergot alkaloids___________________________________________ 261
chapter 17: vasoactive peptides ______________________________________________________________ 273
chapter 18: the eicosanoids: prostaglandins, thromboxanes, leukotrienes, & related compounds ________ 282
chapter 19: nitric oxide _____________________________________________________________________ 290
chapter 20: drugs used in asthma & chronic obstructive pulmonary disease __________________________ 308
section v: drugs that act in the central nervous system _____________________________ 324
chapter 21: introduction to the pharmacology of cns drugs________________________________________ 324
chapter 22: sedative-hypnotic drugs __________________________________________________________ 338
chapter 23: the alcohols ____________________________________________________________________ 357
chapter 24: antiseizure drugs ________________________________________________________________ 372
chapter 25: general anesthetics ______________________________________________________________ 390
chapter 26: local anesthetics _________________________________________________________________ 408
chapter 27: skeletal muscle relaxants _________________________________________________________ 423
chapter 28: pharmacologic management of parkinsonism & other movement disorders ________________ 440
, chapter 29: antipsychotic agents & lithium _____________________________________________________ 457
chapter 30: antidepressant agents ____________________________________________________________ 475
chapter 31: opioid agonists & antagonists ______________________________________________________ 494
chapter 32: drugs of abuse __________________________________________________________________ 512
section vi: drugs used to treat diseases of the blood, inflammation, & gout ____________ 527
chapter 33: agents used in cytopenias; hematopoietic growth factors _______________________________ 527
chapter 34: drugs used in disorders of coagulation _______________________________________________ 543
chapter 35: agents used in dyslipidemia _______________________________________________________ 560
chapter 36: nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, nonopioid
analgesics, & drugs used in gout ______________________________________________________________ 578
section vii: endocrine drugs ___________________________________________________ 596
chapter 37: hypothalamic & pituitary hormones ________________________________________________ 596
chapter 38: thyroid & antithyroid drugs _______________________________________________________ 613
chapter 39: adrenocorticosteroids & adrenocortical antagonists ___________________________________ 631
chapter 40: the gonadal hormones & inhibitors _________________________________________________ 649
chapter 41: pancreatic hormones & glucose-lowering drugs _______________________________________ 668
chapter 42: agents that affect bone mineral homeostasis _________________________________________ 686
section viii: chemotherapeutic drugs____________________________________________ 704
chapter 43: beta-lactam & other cell wall- & membrane-active antibiotics ___________________________ 704
chapter 44: tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins, oxazolidinones, &
pleuromutilins ____________________________________________________________________________ 724
chapter 45: aminoglycosides & spectinomycin __________________________________________________ 740
chapter 46: sulfonamides, trimethoprim, & quinolones ___________________________________________ 754
chapter 47: antimycobacterial drugs __________________________________________________________ 769
chapter 48: antifungal agents ________________________________________________________________ 784
chapter 49: antiviral agents __________________________________________________________________ 802
chapter 50: miscellaneous antimicrobial agents; disinfectants, antiseptics, & sterilants ________________ 820
chapter 51: clinical use of antimicrobial agents__________________________________________________ 840
chapter 52: antiprotozoal drugs ______________________________________________________________ 856
chapter 53: clinical pharmacology of the antihelminthic drugs _____________________________________ 874
chapter 54: cancer chemotherapy ____________________________________________________________ 892
chapter 55: immunopharmacology____________________________________________________________ 912
section ix: toxicology ________________________________________________________ 931
chapter 56: introduction to toxicology: occupational & environmental ______________________________ 931
, chapter 57: heavy metal intoxication & chelators ________________________________________________ 965
chapter 58: management of the poisoned patient _______________________________________________ 979
section x: special topics ______________________________________________________ 993
chapter 59: special aspects of perinatal & pediatric pharmacology _________________________________ 993
chapter 60: special aspects of geriatric pharmacology ___________________________________________ 1002
chapter 61: dermatologic pharmacology ______________________________________________________ 1008
chapter 62: drugs used in the treatment of gastrointestinal diseases _______________________________ 1015
chapter 63: cannabinoid drugs ______________________________________________________________ 1033
chapter 64: therapeutic & toxic potential of over-the-counter agents ______________________________ 1046
chapter 65; dietary supplements & herbal medications __________________________________________ 1066
chapter 66: rational prescribing & prescription writing __________________________________________ 1070
chapter 67: important drug interactions & their mechanisms _____________________________________ 1090
16TH EDITION TEST BANK, (2024)
BY TODD W. VANDERAH
ALL CHAPTERS 1-67| 10 SECTIONS| LATEST VERSION WITH ALL DETAILED ANSWERS| GRADE A+
16th edition
,section i: basic principles _______________________________________________________ 5
chapter 1: introduction: the nature of drugs & drug development & regulation _________________________ 5
chapter 2: drug receptors & pharmacodynamics _________________________________________________ 23
chapter 3: pharmacokinetics & pharmacodynamics: rational dosing & the time course of drug action _____ 43
chapter 4: drug biotransformation _____________________________________________________________ 57
chapter 5: pharmacogenomics ________________________________________________________________ 71
section ii: autonomic drugs ____________________________________________________ 80
chapter 6. Introduction to autonomic pharmacology ______________________________________________ 80
chapter 7: cholinoceptor-activating & cholinesterase-inhibiting drugs _______________________________ 100
chapter 8: cholinoceptor-blocking drugs _______________________________________________________ 118
chapter 9: adrenoceptor agonists & sympathomimetic drugs ______________________________________ 136
chapter 10: adrenoceptor antagonist drugs _____________________________________________________ 154
section iii: cardiovascular-renal drugs ___________________________________________ 172
chapter 11: antihypertensive agents __________________________________________________________ 172
chapter 12: vasodilators & the treatment of angina pectoris_______________________________________ 192
chapter 13: drugs used in heart failure ________________________________________________________ 209
chapter 14: agents used in cardiac arrhythmias _________________________________________________ 226
chapter 15: diuretic agents __________________________________________________________________ 244
section iv: drugs with important actions on smooth muscle _________________________ 261
chapter 16: histamine, serotonin, & the ergot alkaloids___________________________________________ 261
chapter 17: vasoactive peptides ______________________________________________________________ 273
chapter 18: the eicosanoids: prostaglandins, thromboxanes, leukotrienes, & related compounds ________ 282
chapter 19: nitric oxide _____________________________________________________________________ 290
chapter 20: drugs used in asthma & chronic obstructive pulmonary disease __________________________ 308
section v: drugs that act in the central nervous system _____________________________ 324
chapter 21: introduction to the pharmacology of cns drugs________________________________________ 324
chapter 22: sedative-hypnotic drugs __________________________________________________________ 338
chapter 23: the alcohols ____________________________________________________________________ 357
chapter 24: antiseizure drugs ________________________________________________________________ 372
chapter 25: general anesthetics ______________________________________________________________ 390
chapter 26: local anesthetics _________________________________________________________________ 408
chapter 27: skeletal muscle relaxants _________________________________________________________ 423
chapter 28: pharmacologic management of parkinsonism & other movement disorders ________________ 440
, chapter 29: antipsychotic agents & lithium _____________________________________________________ 457
chapter 30: antidepressant agents ____________________________________________________________ 475
chapter 31: opioid agonists & antagonists ______________________________________________________ 494
chapter 32: drugs of abuse __________________________________________________________________ 512
section vi: drugs used to treat diseases of the blood, inflammation, & gout ____________ 527
chapter 33: agents used in cytopenias; hematopoietic growth factors _______________________________ 527
chapter 34: drugs used in disorders of coagulation _______________________________________________ 543
chapter 35: agents used in dyslipidemia _______________________________________________________ 560
chapter 36: nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, nonopioid
analgesics, & drugs used in gout ______________________________________________________________ 578
section vii: endocrine drugs ___________________________________________________ 596
chapter 37: hypothalamic & pituitary hormones ________________________________________________ 596
chapter 38: thyroid & antithyroid drugs _______________________________________________________ 613
chapter 39: adrenocorticosteroids & adrenocortical antagonists ___________________________________ 631
chapter 40: the gonadal hormones & inhibitors _________________________________________________ 649
chapter 41: pancreatic hormones & glucose-lowering drugs _______________________________________ 668
chapter 42: agents that affect bone mineral homeostasis _________________________________________ 686
section viii: chemotherapeutic drugs____________________________________________ 704
chapter 43: beta-lactam & other cell wall- & membrane-active antibiotics ___________________________ 704
chapter 44: tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins, oxazolidinones, &
pleuromutilins ____________________________________________________________________________ 724
chapter 45: aminoglycosides & spectinomycin __________________________________________________ 740
chapter 46: sulfonamides, trimethoprim, & quinolones ___________________________________________ 754
chapter 47: antimycobacterial drugs __________________________________________________________ 769
chapter 48: antifungal agents ________________________________________________________________ 784
chapter 49: antiviral agents __________________________________________________________________ 802
chapter 50: miscellaneous antimicrobial agents; disinfectants, antiseptics, & sterilants ________________ 820
chapter 51: clinical use of antimicrobial agents__________________________________________________ 840
chapter 52: antiprotozoal drugs ______________________________________________________________ 856
chapter 53: clinical pharmacology of the antihelminthic drugs _____________________________________ 874
chapter 54: cancer chemotherapy ____________________________________________________________ 892
chapter 55: immunopharmacology____________________________________________________________ 912
section ix: toxicology ________________________________________________________ 931
chapter 56: introduction to toxicology: occupational & environmental ______________________________ 931
, chapter 57: heavy metal intoxication & chelators ________________________________________________ 965
chapter 58: management of the poisoned patient _______________________________________________ 979
section x: special topics ______________________________________________________ 993
chapter 59: special aspects of perinatal & pediatric pharmacology _________________________________ 993
chapter 60: special aspects of geriatric pharmacology ___________________________________________ 1002
chapter 61: dermatologic pharmacology ______________________________________________________ 1008
chapter 62: drugs used in the treatment of gastrointestinal diseases _______________________________ 1015
chapter 63: cannabinoid drugs ______________________________________________________________ 1033
chapter 64: therapeutic & toxic potential of over-the-counter agents ______________________________ 1046
chapter 65; dietary supplements & herbal medications __________________________________________ 1066
chapter 66: rational prescribing & prescription writing __________________________________________ 1070
chapter 67: important drug interactions & their mechanisms _____________________________________ 1090