4/19/25, 7:07 AM NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT…
NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY
MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM
EXAM SUMMER QRT| MOST RECENT WALDEN
UNIVERSITY|AGRADED
Terms in this set (174)
Serotonin regulates Mood, emotion, feeding, and reproductive behavior
This class of antidepressants SSRIs
binds to
presynaptic SERT and
inhibits them from reuptake
of serotonin to increase
levels in the synaptic cleft
to bind with postsysnaptic
5HT2 receptors
First line therapy for MDD SSRIs
due to milder side effect
profiles
Six Common SSRIs citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
Onset of therapeutic benefit 4-6 weeks
from SSRIs
In addition to MDD, SSRIs also Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
treat
Five Common side effects of Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
SSRIs include
Severe side effect of SSRIs in suicidal ideation
children/adolescents under
age 25 years old
1/22
,4/19/25, 7:07 AM NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT…
Life threatening adverse Serotonin Syndrome
effect of SSRIs, especially
when used in combination
with other serotonergic
drugs (SNRIs, TCAs, MAOIs,
etc.)
Excess accumulation of Serotonin Syndrome
serotonin resulting in
overstimulation of the
nervous system
Seven symptoms of Serotonin Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
Syndrome HYPERreflexia
The treatment for serotonin Cyproheptadine (5-HT2 receptor antagonist)
syndrome
Cyproheptadine treats blocking 5-HT2 receptors (serotonin antagonist)
serotonin syndrome by
When SSRIs or SNRIs are Irritability, headaches, and insomnia
stopped abruptly, common
symptoms of withdrawal
include
Medicine specific side effect Prolonged QT interval (normal=0.4.-0.44 seconds)
of citalopram
This SSRI is pregnancy Paroxetine
category D due to
associations with congenital
heart defects
All SSRIs but paroxetine (D) C
are pregnancy category
Three SSRIs that are fluoxetine, fluvoxamine, and paroxetine
inhibitors of
Cytochrome P450
enzymes
Five common SNRIs include duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
This antidepressant class SNRIs
of medications works by
binding to presynaptic SERT
2/22
, 4/19/25, 7:07 AM NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT…
and NET to inhibit them
from reuptake of
serotonin and
norepinephrine to increase
their levels in the synaptic
cleft
In addition to MDD SNRIs Anxiety and neuropathic pain (peripheral neuropathy)
treat
Medication specific urinary incontinence and Fibromyalgia
indications of duloxetine:
Medication specific social anxiety, panic disorders, PTSD, OCD, postmenopausal hot
indications of venlafaxine: flashes
Six common side effects of Insomnia, nausea, sexual dysfunction, hypertension, sweating,
SNRIs include: headaches
Severe side effect of SNRIs in suicidal ideation
children/adolescents under
age 25 years old:
Life threatening adverse Serotonin Syndrome
effect of SNRIs, especially
when used in combination
with other serotonergic
drugs:
This SNRI is an inhibitor of venlafaxine
Cytochrome P450
enzymes:
This SNRI is hepatotoxic: duloxetine
MAOIs increase the levels of: Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: alertness and focus
Dopamine regulates: cognitive function, motivation, and awakeness
In the synaptic cleft, Serotonin, Norepinephrine, and Dopamine
Monoamine Oxidase A breaks
down:
In the synaptic cleft, Dopamine
Monoamine Oxidase B breaks
down:
Atypical depression (mood responds to positive events
MAOIs are especially effective
in:
3/22
NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY
MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM
EXAM SUMMER QRT| MOST RECENT WALDEN
UNIVERSITY|AGRADED
Terms in this set (174)
Serotonin regulates Mood, emotion, feeding, and reproductive behavior
This class of antidepressants SSRIs
binds to
presynaptic SERT and
inhibits them from reuptake
of serotonin to increase
levels in the synaptic cleft
to bind with postsysnaptic
5HT2 receptors
First line therapy for MDD SSRIs
due to milder side effect
profiles
Six Common SSRIs citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
Onset of therapeutic benefit 4-6 weeks
from SSRIs
In addition to MDD, SSRIs also Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
treat
Five Common side effects of Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
SSRIs include
Severe side effect of SSRIs in suicidal ideation
children/adolescents under
age 25 years old
1/22
,4/19/25, 7:07 AM NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT…
Life threatening adverse Serotonin Syndrome
effect of SSRIs, especially
when used in combination
with other serotonergic
drugs (SNRIs, TCAs, MAOIs,
etc.)
Excess accumulation of Serotonin Syndrome
serotonin resulting in
overstimulation of the
nervous system
Seven symptoms of Serotonin Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
Syndrome HYPERreflexia
The treatment for serotonin Cyproheptadine (5-HT2 receptor antagonist)
syndrome
Cyproheptadine treats blocking 5-HT2 receptors (serotonin antagonist)
serotonin syndrome by
When SSRIs or SNRIs are Irritability, headaches, and insomnia
stopped abruptly, common
symptoms of withdrawal
include
Medicine specific side effect Prolonged QT interval (normal=0.4.-0.44 seconds)
of citalopram
This SSRI is pregnancy Paroxetine
category D due to
associations with congenital
heart defects
All SSRIs but paroxetine (D) C
are pregnancy category
Three SSRIs that are fluoxetine, fluvoxamine, and paroxetine
inhibitors of
Cytochrome P450
enzymes
Five common SNRIs include duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
This antidepressant class SNRIs
of medications works by
binding to presynaptic SERT
2/22
, 4/19/25, 7:07 AM NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT…
and NET to inhibit them
from reuptake of
serotonin and
norepinephrine to increase
their levels in the synaptic
cleft
In addition to MDD SNRIs Anxiety and neuropathic pain (peripheral neuropathy)
treat
Medication specific urinary incontinence and Fibromyalgia
indications of duloxetine:
Medication specific social anxiety, panic disorders, PTSD, OCD, postmenopausal hot
indications of venlafaxine: flashes
Six common side effects of Insomnia, nausea, sexual dysfunction, hypertension, sweating,
SNRIs include: headaches
Severe side effect of SNRIs in suicidal ideation
children/adolescents under
age 25 years old:
Life threatening adverse Serotonin Syndrome
effect of SNRIs, especially
when used in combination
with other serotonergic
drugs:
This SNRI is an inhibitor of venlafaxine
Cytochrome P450
enzymes:
This SNRI is hepatotoxic: duloxetine
MAOIs increase the levels of: Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: alertness and focus
Dopamine regulates: cognitive function, motivation, and awakeness
In the synaptic cleft, Serotonin, Norepinephrine, and Dopamine
Monoamine Oxidase A breaks
down:
In the synaptic cleft, Dopamine
Monoamine Oxidase B breaks
down:
Atypical depression (mood responds to positive events
MAOIs are especially effective
in:
3/22
