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Sulfamethoxazole-Trimethoprim/TMP-SMZ (Contraindications) - CORRECT ANSWER-
Br feeding infants <2mo. Hypersensitivity, term pregnancy, megaloblastic anemia,
chancroid, traveler's diarrhea
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Side Effects) - CORRECT ANSWER-Mild
to moderate rash, photosensitivity
GI distress, stomatitis, crystalluria
Fatigue, depression, headache, dizziness
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Adverse Reactions) - CORRECT
ANSWER-Blood dyscrasias
Stevens-Johnson syndrome
Renal failure
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Nursing Interventions) - CORRECT
ANSWER-Administer with full glass of water 1 hour before meals or 2 hours after meals.
Increase fluid intake.
Monitor for sore throat, bruising, bleeding.
Monitor CBC.
Check for superinfection.
Advise client not to take with antacids.
Tell client to avoid direct sunlight.
Use alternate forms of OCP
Avoid OTC (asa, vit.C)
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Drug Interaction) - CORRECT ANSWER-
Warfarin
Increases anticoagulation
Oral hypoglycemic
Increases hypoglycemia
Sulfamethoxazole-Trimethoprim/TMP-SMZ (class) - CORRECT ANSWER-
Sulfonamides
Nitrofurantoin (Macrodantin) (class) - CORRECT ANSWER-Anti-infective
, Nitrofurantoin (Macrodantin) (Actions/uses) - CORRECT ANSWER-Inhibits bacterial
UTIs caused by E coli, Klebsiella, Pseudomonas, Proteus vulgaris & morganii, Staph
aureus, & epidermidis, enterococcus, salmonella, shigella
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Actions) - CORRECT ANSWER-Inhibit
bacterial synthesis of folic acid
Bacteriostatic
Fights gram - bacteria
Proteus, Klebsiella, E. coli, Chlamydia
Sulfamethoxazole-Trimethoprim/TMP-SMZ (uses) - CORRECT ANSWER-Otitis media,
respiratory infections
UTIs, prostatitis, gonorrhea
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Routes) - CORRECT ANSWER-Oral, IV,
topical, ophthalmic
Nitrofurantoin (Macrodantin) (Contraindications) - CORRECT ANSWER-Infant <1 mo,
hypersensitivity, anuria, severe renal disease CCr <60 mL/min, term pregnancy, labor,
delivery
Nitrofurantoin (Macrodantin) (side effects) - CORRECT ANSWER-Dizziness, h/a,
drowsiness, peripheral neuropathy, chills, confusion, vertigo, CP, n/v/d, abd pain, loss of
appetite, pruritus, rash, angioedema, alopecia, tooth staining, arthralgia, myalgia,
numbness, cough, dyspnea, pneumonitis, pulmonary fibrosis or infiltrate, SLE-like
syndrome
Nitrofurantoin (Macrodantin) (Adverse reactions) - CORRECT ANSWER-Bundle-branch
block, cholestatic jaundice, pseudomembranous coilitis, hepatitis, pancreatitis, anemia,
agranulocytosis, hemolytic anemia, leukopenia, thrombocytopenia, exfoliative
dermatitis, Stevens-Johnson syndrome, superinfection
Nitrofurantoin (Macrodantin) (Nursing Implications) - CORRECT ANSWER-Report
continued symptoms
Take with food or milk, avoid ETOH
Protect from freezing, shake well
May cause drowsiness, seek aid with walking & other activities (driving or operating
machinery)
Monitor blood glucose in diabetes
Instruct urine may turn urine rust-yellow to brown
Report fever, diarrhea with mucus, pus, or blood
Phenazopyridine HCL (Pyridium) (Class) - CORRECT ANSWER-Urinary Analgesic