ASCP MLT EXAM/ PRACTICE AND STUDY GUIDE EXAM NEWEST 2025/2026 TEST BANK| COMPLETE QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) ALREADY GRADED A+| ASCP MLT EXAM PREP 2025|| BRAND NEW!!

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ASCP MLT EXAM/ PRACTICE AND STUDY GUIDE
EXAM NEWEST 2025/2026 TEST BANK| COMPLETE
QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) ALREADY GRADED A+| ASCP
MLT EXAM PREP 2025|| BRAND NEW!!



Which of the following organs is responsible for the maturation of T
lymphocytes and regulation of their expression of CD4 and CD8?
a. Spleen
b. Liver
c. Thymus
d. Bone marrow - Correct Answer - c. Thymus


The best source of active bone marrow from a 20-year-old would be:
a. Iliac crest
b. Femur
c. Distal radius
d. Tibia - Correct Answer - a. Iliac crest


Physiologic programmed cell death is termed:
a. Angiogenesis
b. Apoptosis
c. Aneurysm


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d. Apohematics - Correct Answer - b. Apoptosis


Which organ is the site of sequestration of platelets?
a. Liver
b. Thymus
c. Spleen
d. Bone marrow - Correct Answer - c. Spleen


Which one of the following cells is a product of the CLP?
a. Megakaryocyte
b. T lymphocyte
c. Erythrocyte
d. Granulocyte - Correct Answer - b. T lymphocyte


What growth factor is produced in the kidneys and is used to treat
anemia associated with kidney disease?
a. EPO
b. TPO
c. G-CSF
d. KIT ligand - Correct Answer - a. EPO


Which one of the following cytokines is required very early in the
differentiation of a hematopoietic stem cell?
a. IL-2

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b. IL-8
c. EPO
d. FLT3 ligand - Correct Answer - d. FLT3 ligand


Hematopoietic stem cells produce all lineages of blood cells in sufficient
quantities over the lifetime of an individual because they:
a. Are unipotent
b. Have the ability of self-renewal by asymmetric division
c. Are present in large numbers in the bone marrow niches
d. Have a low mitotic potential in response to growth factors - Correct
Answer - b. Have the ability of self-renewal by asymmetric division


Which of the following is an erythrocyte progenitor?
a. Pronormoblast
b. Reticulocyte
c. CFU-E
d. Orthochromic normoblast - Correct Answer - c. CFU-E


Which of the following is the most mature normoblast?
a. Orthochromic normoblast
b. Basophilic normoblast
c. Pronormoblast
d. Polychromatic normoblast - Correct Answer - a. Orthochromic
normoblast


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Which of the following is not related to the effects of erythropoietin?
a. The number of divisions of a normoblast
b. The formation of pores in sinusoidal endothelial cells for marrow
egress
c. The time between mitoses of normoblasts
d. The production of antiapoptotic molecules by erthroid progenitors -
Correct Answer - b. The formation of pores in sinusoidal endothelial
cells for marrow egress


Hypoxia stimulates RBC production by:
a. Inducing more pluripotent stem cells into erythroid lineage
b. Stimulating EPO production by the kidney
c. Increasing the number of RBC mitoses
d. Stimulating the production of fibronectin by macrophages of the bone
marrow - Correct Answer - b. Stimulating EPO production by the kidney


In the bone marrow, RBC precursors are located:
a. In the center of the hematopoietic cords
b. Adjacent to megakaryocytes along the adventitial cell lining
c. Surrounding fat cells in apoptotic islands
d. Surrounding macrophages in erythroid islands - Correct Answer - d.
Surrounding macrophages in erythroid islands


What single feature of normal RBCs is most responsible for limiting
their life span?

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