BIO 351 Module 3 2025 Questions and
Answers 100% Pass
The neural tube forms from the folding of the neural plate. Which region of the neural
tube is the first to close? - ✔✔B
The brain is derived from which of the following: - ✔✔ectoderm
The nervous system begins as a flat neural plate that runs along the midline from rostral
to caudal. Folding is initiated with the [ Select ] anchored to the [ Select ] and changes
shape while the epidermal cells move toward the dorsal midline. - ✔✔medial
hingepoint cells
notochord
Crosstalk between the __________ and ectoderm establish patterning that forms the
neural tube. - ✔✔mesoderm
Which of the following defects is a severe open neural tube defect caused by failure of
rostral neural tube closure? - ✔✔anencephaly
The neural tube forms from the folding of the neural plate. Which region of the neural
plate fuses together to form the dorsal neural tube? - ✔✔C
Which of the following is an occult, and not an open, neural tube defect? - ✔✔Spina
bifida occulta
Folate promotes neural tube closure. On a cellular basis, it is necessary for
__________________. - ✔✔nucleotide biosynthesis
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, The neural tube is regionalized by developmental gene regulation. Which of the
following correctly matches the gene and specified region? - ✔✔Shh - ventralizing the
neural tube
Which of the following regulates the segmentation of the hindbrain rhombomeres? -
✔✔Hox gene expression
Which of these central nervous system structures are correctly listed in a rostral to
caudal order? - ✔✔Cerebrum, Pons, Spinal Cord
Which of the following represent antagonistic cues used in patterning the
rostral/caudal axis if the neural tube: - ✔✔RA/FGF8
In the diagram of neural tube folding, indicate the region of tissue that will eventually
form the neural crest. - ✔✔C
The process the neural crest cells use to delaminate from the dorsal neural tube is
__________ . - ✔✔EMT, epithelial mesenchymal transition
Neural crest cells derive from the [ Select ] layer and give rise to the [ Select ]. -
✔✔ectoderm
peripheral nervous system
Neural crest cells can differentiate into multiple cells types. The following statement is
TRUE or FALSE: A unique feature of neural crest cells is that they have intrinsic
programs that predetermine their fate prior to delamination from the neural tube;
Neural crest cells are not influenced by extrinsic cues to instruct the outcome of the
ultimate cell fate. - ✔✔False
In developing radial glia, ____________ and _________ are necessary to maintain the
progenitor state. Pick the best answer to fill in the blank below - ✔✔Notch, Par3
COPYRIGHT © 2025 BY SOPHIA BENNETT, ALL RIGHTS RESERVED 2
Answers 100% Pass
The neural tube forms from the folding of the neural plate. Which region of the neural
tube is the first to close? - ✔✔B
The brain is derived from which of the following: - ✔✔ectoderm
The nervous system begins as a flat neural plate that runs along the midline from rostral
to caudal. Folding is initiated with the [ Select ] anchored to the [ Select ] and changes
shape while the epidermal cells move toward the dorsal midline. - ✔✔medial
hingepoint cells
notochord
Crosstalk between the __________ and ectoderm establish patterning that forms the
neural tube. - ✔✔mesoderm
Which of the following defects is a severe open neural tube defect caused by failure of
rostral neural tube closure? - ✔✔anencephaly
The neural tube forms from the folding of the neural plate. Which region of the neural
plate fuses together to form the dorsal neural tube? - ✔✔C
Which of the following is an occult, and not an open, neural tube defect? - ✔✔Spina
bifida occulta
Folate promotes neural tube closure. On a cellular basis, it is necessary for
__________________. - ✔✔nucleotide biosynthesis
COPYRIGHT © 2025 BY SOPHIA BENNETT, ALL RIGHTS RESERVED 1
, The neural tube is regionalized by developmental gene regulation. Which of the
following correctly matches the gene and specified region? - ✔✔Shh - ventralizing the
neural tube
Which of the following regulates the segmentation of the hindbrain rhombomeres? -
✔✔Hox gene expression
Which of these central nervous system structures are correctly listed in a rostral to
caudal order? - ✔✔Cerebrum, Pons, Spinal Cord
Which of the following represent antagonistic cues used in patterning the
rostral/caudal axis if the neural tube: - ✔✔RA/FGF8
In the diagram of neural tube folding, indicate the region of tissue that will eventually
form the neural crest. - ✔✔C
The process the neural crest cells use to delaminate from the dorsal neural tube is
__________ . - ✔✔EMT, epithelial mesenchymal transition
Neural crest cells derive from the [ Select ] layer and give rise to the [ Select ]. -
✔✔ectoderm
peripheral nervous system
Neural crest cells can differentiate into multiple cells types. The following statement is
TRUE or FALSE: A unique feature of neural crest cells is that they have intrinsic
programs that predetermine their fate prior to delamination from the neural tube;
Neural crest cells are not influenced by extrinsic cues to instruct the outcome of the
ultimate cell fate. - ✔✔False
In developing radial glia, ____________ and _________ are necessary to maintain the
progenitor state. Pick the best answer to fill in the blank below - ✔✔Notch, Par3
COPYRIGHT © 2025 BY SOPHIA BENNETT, ALL RIGHTS RESERVED 2
