Chapter 5 Immunity,
Inflammation, Infection Lecture
9/4
Physical and Chemical Barriers
Skin and mucous membranes = 1st line of defense
Phagocytosis and inflammation = 2nd line of defense
sweat glands, sebaceous glands, acidic secretions, antibody immunoglobin
Immune Response
Antigen (triggers response) and Antibodies aka immunoglobulins
Innate (natural Immunity) Present in body at birth, not dependent on a
specific immune response
, Acquired immunity - develops after birth. bodys natural immune response to
antigens. Depends on development and functioning of B and T lymphocytes
(white blood cells)
Active acquired immunity - developed after direct contact with an antigen
through illness or vaccination
Passive acquired immunity - temporary, received from their mothers
breastmilk/placenta
Once the body has been exposed to an antigen through illness or vaccination,
antibodies develop and retain memory for the antigen. If the body is exposed to
the same antigen later, the antibodies can react quickly to fight off disease.
Organs involved in immunity
Leukocytes WBC have the ability to phagocyte/ingest bacteria
5 types of leukocytes:
Neutrophils - fights bacterial infections
Monocytes - in the blood for approx 1 day before they enter
tissue→macrophages→ ingest foreign antigens
Eosinophils - fight parasitic infections and allergic reactions
Basophils - initiate the inflammatory response and release histamine
Lymphocytes, thymus, bone marrow, lymph nodes, spleen, liver
Inflammation, Infection Lecture
9/4
Physical and Chemical Barriers
Skin and mucous membranes = 1st line of defense
Phagocytosis and inflammation = 2nd line of defense
sweat glands, sebaceous glands, acidic secretions, antibody immunoglobin
Immune Response
Antigen (triggers response) and Antibodies aka immunoglobulins
Innate (natural Immunity) Present in body at birth, not dependent on a
specific immune response
, Acquired immunity - develops after birth. bodys natural immune response to
antigens. Depends on development and functioning of B and T lymphocytes
(white blood cells)
Active acquired immunity - developed after direct contact with an antigen
through illness or vaccination
Passive acquired immunity - temporary, received from their mothers
breastmilk/placenta
Once the body has been exposed to an antigen through illness or vaccination,
antibodies develop and retain memory for the antigen. If the body is exposed to
the same antigen later, the antibodies can react quickly to fight off disease.
Organs involved in immunity
Leukocytes WBC have the ability to phagocyte/ingest bacteria
5 types of leukocytes:
Neutrophils - fights bacterial infections
Monocytes - in the blood for approx 1 day before they enter
tissue→macrophages→ ingest foreign antigens
Eosinophils - fight parasitic infections and allergic reactions
Basophils - initiate the inflammatory response and release histamine
Lymphocytes, thymus, bone marrow, lymph nodes, spleen, liver
