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ASATT REVIEW QUESTIONS AND ANSWERS

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ASATT REVIEW QUESTIONS AND ANSWERS

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ASATT REVIEW QUESTIONS AND ANSWERS
The ASATT was established in this year:

A. 1986
B. 1989
C. 1996
D. 2001 - Answers :1989

ASATT was established in New Orleans, LA, in 1989

The first recorded use of anesthesia support personnel occurred in _____________.

A. England
B. Australia
C. Louisiana
D. China
E. California - Answers :England

The first recorded use of anesthesia support personnel occurred in England in late
1930s

ASATT issued its very first written certification exam for the technician in____________.

A. 1889
B. 1993
C. 1996
D. 2001
E. 2010 - Answers :1996

The certification exam is administered in accordance with standards developed by:

A. ASA
B. AANA
C. APSF
D. NOCA
E. JCAHO - Answers :NOCA
National Organization for Competency Assurance

Certification for both the technologist and technician exams is granted on a:

A. Four-year basis
B. Rotation of every other year
C. Two-year basis
D. Yearly basis - Answers :Two-year basis

,The Item/test writing committee is composed of:

A. Anesthesiologists
B. CRNAs
C. Corporate representatives
D. Anesthesia technicians & technologist - Answers :Anesthesiologists
CRNAs
Corporate representatives

Anesthesia technicians & technologist along with a representative from the test writing
development company

A certified anesthesia technician must show proof of the number of CEHs in a 2-year
period:

A. 30
B. 20
C. 120
D. 125
E. 10 - Answers :20 CEHs for every two years for re-certification.

Anesthesia Technologist has to have 30 CEHs.

How would drug onset and duration of action be affected in a patient with heart failure
(low cardiac output)?

A. Speed drug onset
B. Increase metabolism of the drug
C. Shorten the duration of action
D. Slow the onset - Answers :Slow onset

A patient with reduced cardiac output, as in heart failure, will circulate the blood more
slowly to the target organs, resulting in a delay in onset of action. The duration of action
is usually, but not always, prolonged due to reduced blood flow to the liver (reduced
metabolism) and kidneys (reduced elimination).

What process is responsible for the offset of effects of a bolus of propofol?

A. First pass effect
B. Redistribution
C. P450 enzyme reduction
*D. Increased renal blood flow - Answers :Redistribution

The bolus of propofol is mixed and distributed rapidly to the central compartment and to
the vessel-rich group. Subsequently, the plasma level falls as the propofol is
redistributed to muscles and the vessel poor group.

,Dysfunction of what organ systems will increase the elimination half-life of many
anesthetic drugs?

A. Liver
B. Heart
C. Kidney - Answers :Liver
Heart
Kidney

Many drugs are metabolized in the liver, while many others are excreted unchanged by
the kidneys. Any condition that reduces blood flow to the liver or kidneys can reduce the
amount of drug that is cleared, which will cause an increase in the half-life of the drug.

Which of the following statements is false?

A. Oral administration of drugs may be subject to the first pass effect.
B. IV administration is the route with the fastest onset of drug effects.
C. Inhaled drugs cannot be absorbed into the bloodstream.
D. Certain drugs may only be administered by certain routes.
E. Appropriate drug dose may differ depending upon the route of administration. -
Answers :Inhaled drugs cannot be absorbed into the bloodstream.

Many drugs including inhaled anesthetics, nitric oxide, and lidocaine are all taken up
into the bloodstream after inhaled administration. Orally administered drugs are
absorbed by the gut and taken up in the bloodstream. From there, the blood passes
through the portal circulation in the liver before mixing with systemic circulation. As the
blood passes through the liver, it has the opportunity to metabolize the drug. Drugs
given intravenously have the fastest onset because drugs are delivered to their target
organs by the bloodstream, so the rate of onset is largely determined by how long it
takes for a drug to get to the bloodstream. A critical safety concern is making sure the
right drug in the right dose is given by the right route. Some drugs are toxic if given by
one route but not another. Other drugs have 100-fold different doses depending upon
the route of administration.

Half-life is defined as:

A. The half way to the expiration date for the drug
B. The time required for the amount of drug in the body to decrease by 50%
C. The dose of drug that is effective in 50% of patients
D. One half the volume of distribution - Answers :the time required for the amount of
drug in the body to decrease by 50%

Drugs are gradually eliminated from the body. Some are eliminated at a constant rate
(xxx amount of drug per hour --- zero-order kinetics). With the vast majority of drugs, the
amount of drug eliminated is dependent upon the concentration of the drug --- a fixed

, percentage of the drug, not a fixed amount, is eliminated each hour --- first-ordered
kinetics. The half-life is the amount of time it takes for 50% of the drug to be eliminated.

What is pharmacodynamics?

A. The effect of the drug on the body
B. Drugs acting on a cell
C. Drugs acting on a molecular level
D. Drugs effect on an organ system - Answers :The effect of the drug on the body
drugs acting on a cell
Drugs acting on a molecular level
Drugs effect on a organ system

Receptors site are ______________ and cell membranes are ________________?

A. Hydrophilic and Hydrophobic
B. Hydrophilic and Hydrophilic
C. Hydrophobic and Lipophilic
D. Lipophilic and Lipophilic - Answers :Hydrophilic; Hydrophobic

Cell membranes are made of lipid and are hydrophobic (repels charged molecules or
water). They are also lipophilic (accommodate fat-soluble molecules, those that are not
charged). Receptors can attach to ionized molecules and send a message through the
cell membrane to effect change within the cell.

Aspirin is a __________________ of platelet clotting function.

A. Competitive agonist
B. Competitive antagonist
C. Noncompetitive agonist
D. Noncompetitive antagonist - Answers :Noncompetitive antagonist

It attaches to platelets irreversibly; in other words, aspirin cannot be removed from its
receptor on the platelet with another competitor ligand. Competitive antagonist compete
for binding to the receptor with other molecules. The concentration of the molecules and
the Kd of the molecules determine which competitor binds more receptors.

Which of the following can cause adverse drug reactions?

A. overdose
B. Metabolites
C. Allergy - Answers :All of the above

Adverse reactions can be dose related, and the more narrow the therapeutic window,
the more likely that adverse reactions due to overdose will occur. Breakdown of drugs

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