NU 214-1 Medication Classifications: Anticoagulants Mason
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In laymen's terms, what are anticoagulants also known as?
Ans: Blood thinners
What does coagulation mean?
Ans: Blood clumping
Coagulation modifier drugs are some of the *most dangerous* drugs used
today. Why?
Ans: Because of the increased risk of bleeding
The coagulation system is called the __________ ___________.
Ans: Clotting Cascade
*each factor in the system activates the next
What is the result at the end of the process?
Ans: Fibrin
-chemical that forms blood clots
In the Clotting Cascade, what does factor Xa (10a) do?
Ans: Converts prothrombin to thrombin
In the Clotting Cascade, what does thrombin do?
Ans: Converts fibrinogen to fibrin
In the Clotting Cascade, what does factor XIII (13) do?
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Ans: Converts fibrin to a fibrin clot
Once a clot forms in the body, the __________________ system is used to
break up a clot.
Ans: The Fibrinolytic System
In The Fibrinolytic System, what does tissue plasminogen activator (TPA) do?
Ans: Cause formation of plasminogen
In The Fibrinolytic System, what does plasminogen do?
Ans: Creates plasmin
The Fibrinolytic System, what does plasmin do?
Ans: Breaks up the clot
Name the different types of coagulation modifier drugs.
Ans: -Anticoagulants (Prevent clot from forming)
-Antiplatelets (Prevents platelets from clumping = clot prevention)
-Thrombolytics (Breaks apart clot = Tx)
-Antifibrinolytics (Causes clotting to occur)
*Anticoagulants*
Ans:
Anticoagulants are also called...
Ans: antithrombotic drugs
How do Anticoagulants work?
Ans: They inhibit the action/formation of clotting factors and stop te cascade
If a clot has already formed it will not break it up- only prevents.
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