ANSWERS GRADED A+
✔✔Cholinesterase inhibitors are used in tx of what conditon? - ✔✔Alzheimer's disease.
MOA block normal breakdown of acetylocholine which increases their levels and
duration of action in the CNS and PNS (neuromuscular junction). Also used in tx of
myasthenia gravis Ex: neostigmine, donepezil, galantamine, rivastigmine
✔✔What are some diseases/disorders/conditions are anticonvulsants used to treat
other than seizure disorders? - ✔✔migraine HA prevention, bipolar DO, epilepsy
Examples: carbamazepine(Tegretol), gabapentin(Neurontin), phenobarbital,
topiramate(Topamax)
✔✔Anti-seizure med used for prophylactic tx of migraines - ✔✔topiramate
✔✔Anti-seizure med that is also an anti-arrhythmic - ✔✔phenytoin(Dilantin)
✔✔Anti-seizure med w/black box warning for blood dyscrasias and serious derm rxns -
✔✔carbamazepine(Tegretol)
✔✔First-line agent for early onset migraine - ✔✔NSAIDs
✔✔Hallucinations may occur if __________ is stopped abruptly - ✔✔baclofen
✔✔atomoxetine(Straterra), clonidine, and guanfacine are used in tx of which DO? -
✔✔ADHD
✔✔initial intervention for infrequent migraine HA - ✔✔HA diary
✔✔Meds that may cause QT prolongation - ✔✔methadone, tricyclic antidepressants,
amiodarone
✔✔CI for a triptan includes - ✔✔htn, CAD, MAOI use. Triptans used to ease migraine
symptoms by calming overactive nerves in the brain and vasoconstriction of blood
vessels in the brain
✔✔What to give for hives and wheezing r/t pb? - ✔✔epinephrine IM
✔✔Beta blockers have been used to treat _____________, _________, ____________
- ✔✔post MI, HTN, HF
✔✔Drug route for 100% bioavailability - ✔✔IV
, ✔✔Chronic renal failure will affect ___________ element of pharmacokinetics -
✔✔excretion
✔✔Adrenergic antagonists or alpha blockers cause ____________________ -
✔✔vasodilation
✔✔in addition to lowering BP, alpha blockers are used in tx of ________ - ✔✔BPH
✔✔symptoms of BPH - ✔✔urinary frequency and urgency, nocturia, hesitancy and
difficulty continuing to urinate, reduced force and size of urinary stream ("weak" stream),
sensation of incomplete bladder emptying, straining to begin urination, post-void
dribbling or leaking, hematuria, enlarged prostate
✔✔Common side effect of ACE inhibitors - ✔✔dry cough
✔✔Angina is a pain caused by _________________ - ✔✔cardiac ischemia
✔✔All pts with angina should receive what drug for prophylaxis of a myocardial
infarction? - ✔✔aspirin- antiplatelet
✔✔lifestyle modifications to reduce cardiac risk include - ✔✔Wt loss (at least 10lbs),
stop smoking, daily exercise
✔✔Pt w/ heart failure, angina w/walking and slight limitation of activity is what class? -
✔✔Class II
✔✔pt is taking hydrochlorothiazide(HCTZ) for HTN. What lab is most impt to monitor? -
✔✔K, for hypokalemia.
Hypokalemia can result in abnormal heart rhythms, cramp and twitch muscles.
HCTZ, thiazide diuretic, removes excess salt and water
✔✔cardiac remodeling in HF - ✔✔Worsens HF. The wall of the left ventricle thickens
and enlarges in an attempt to compensate for the increased workload.
✔✔class of medication in pts post MI to prevent cardiac remodeling - ✔✔ACE inhibitors.
ACE inhibitors are known to increase tissue bradykinin accumulation. Bradykinin has
antigrowth effects and reduces vasomotor tone.
✔✔When tx hyperlipidemia, calculation ____________ risk will help to determine tx. -
✔✔ASCVD risk, Atherosclerotic cardiovascular disease
✔✔Class of medication contraindicated in pts w/liver failure - ✔✔HMG-CoA
inhibitors(Statins). Because all statins are hepatically cleared and can cause elevations