Chapter 2 questions and verified correct
gh gh gh gh gh gh g
answers
h
Differentiationgh-ghcorrectghanswers-
theghprocessghbyghwhichghanghunspecializedghcellghbecomesghspecializedghintoghoneghofghtheghm
anyghcellghtypesghthatghmakeghupghtheghbody.
Commitmentgh-ghcorrectghanswers-
describesghaghstateghinghwhichghaghcell'sghdevelopmentalghfateghhasghbecomeghrestrictedghevengh
thoughghitghisghnotghyetghdisplayingghovertghchangesghinghcellularghbiochemistryghandghfunction.
Specificationgh-ghcorrectghanswers-
theghfirstghstageghofghcommitmentghofghcellghorghtissueghfateghduringghwhichghtheghcellghorghtissueghi
sghcapableghofghdifferentiatingghautonomouslygh(i.e.,ghbyghitself)ghwhenghplacedghinghanghenviron
mentghthatghisghneutralghwithghrespectghtoghtheghdevelopmentalghpathway.ghAtghtheghstageghofghsp
ecification,ghcellghcommitmentghisghstillghcapableghofghbeingghreversed.
Determinationgh-ghcorrectghanswers-
theghstageghofghcommitmentghfollowingghspecification;ghtheghdeterminedghstage,ghassumedghirr
eversible,ghisghwhenghaghcellghorghtissueghisghcapableghofghdifferentiatedghautonomouslyghevenghw
henghplacedghintoghaghnon-neutralghenvironment.
AutonomousghSpecificationgh-ghcorrectghanswers-
aghmodeghofghcellghcommitmentghinghwhichghtheghblastomereghinheritsghaghdeterminant,ghusuallygh
aghsetghofghtranscriptionghfactorsghfromghthegheggghcytoplasm,ghandghtheseghtranscriptionghfactor
sghregulateghgeneghexpressionghtoghdirectghtheghcellghintoghaghparticularghpathghofghdevelopment.
MorphogeneticghDeterminantsgh-ghcorrectghanswers-
transcriptionghfactorsghorghtheirghmRNAsghthatghwillghinfluenceghtheghcell'sghdevelopment.
SyncytialghSpecificationgh-ghcorrectghanswers-
theghinteractionsghofghnucleighandghtranscriptionghfactors,ghwhichgheventuallyghresultghinghcellghsp
ecification,ghthatghtakeghplaceghinghaghcommonghcytoplasm,ghasghinghtheghearlyghDrosophilaghemb
ryo.
Determinedgh-ghcorrectghanswers-
committedghtoghaghgivenghfate.ghAghcellghisghdeterminedghifghitghmaintainsghitsghdevelopmentalghma
turationghtowardghitsghfateghevenghwhenghplacedghinghaghnewghenvironment.
CytoplasmicghDeterminationghFactorsgh-ghcorrectghanswers-
factorsghfoundghinghtheghcytoplasmghofghaghcellghthatghdetermineghcellghfate.ghExample:ghgradients
ghofghdifferentghcytoplasmicghdeterminationghfactorsghthatghdictateghcellghfateghalongghtheghanterio
r-posteriorghaxisghareghfoundghinghtheghsyncytialghblastodermghofghtheghDrosophilaghembryo.
TranscriptionghFactorsgh-ghcorrectghanswers-
aghproteinghthatghbindsghtoghDNAghwithghpreciseghsequenceghrecognitionghforghspecificghpromoter
s,ghenhancers,ghorghsilencers.
Morphogensgh-ghcorrectghanswers-
diffusibleghbiochemicalghmoleculesghthatghcanghdetermineghtheghfateghofghaghcellghbyghtheirghconc
entrations,ghinghthatghcellsghexposedghtoghhighghlevelsghofghaghmorphogenghwillghactivateghdifferen
tghgenesghthanghthoseghexposedghtoghlowerghlevels.