WGU D115 MASTER SET-ADVANCED PATHOPHYSIOLOGY FOR THE
ADVANCED PRACTICE NURSE / ACTUAL EXAM TEST STUDY GUIDE /
(340+ Q&A) ACCURATE EXPERT VERIFIED FOR GUARANTEED PASS /
LATEST UPDATE
Which type of genetic disease affects males more frequently than females? - (answers)Sex-
Linked recessive. Since males only have one X and one Y, if the affected chromosome has the
illness, it will be expressed.
In which two conditions are chromosomal abnormalities the leading known cause? -
(answers)Intellectual disability and fetal miscarriage. Chromosome abnormalities are the leading
known cause of intellectual disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies? - (answers)Chorionic villus sampling
(CVS), amniocentesis, and preimplantation genetic testing (PGT) are examples of prenatal
diagnostic studies and are performed in vitro. CVS is a form of genetic testing that provides
genetic information found in utero and is usually performed between weeks 11 and 14 of
pregnancy. An amniocentesis is a form of genetic testing that evaluates amniotic fluid and is
usually performed during the second trimester, between weeks 15 and 20 of pregnancy. PGT is
performed on the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote having one chromosome
with a normal complement of genes and one chromosome with a missing gene? - (answers)Cri
du chat syndrome (translated as "cry of the cat") is caused by a DNA deletion. This term
describes the cry often heard from a baby affected by the syndrome. Cri du chat syndrome can
present as a microcephalic, low birth-weight baby with a piercing cry.
How can an X-linked recessive disease skip generations? - (answers)The disease can be
transmitted through female carriers.
心也是善良与爱的源泉。
,Since females have two copies of the X chromosome, the mother may provide an unaffected X to
a daughter or son. Furthermore, a daughter may not show signs of the disease because she has
the other X (the only X the father can give to a female) to cancel it out.
Which type of risk is referred to as the ratio of the disease rate among the entire population to the
disease rate in an unexposed population? - (answers)Relative risk is a ratio of probability, not an
actual occurrence of disease.
What are the empirical risks for most multifactorial diseases based on? - (answers)Many factors
from lifestyle to genetics affect multifactorial diseases. Observation and evaluation of each case
individually provides the most thorough and accurate assessment.
What refers to the silenced gene of a gene pair. - (answers)The imprinted gene is the silent gene
of a gene pair.
What is the primary reason that some older adults have impaired inflammation and wound
healing? - (answers)The underlying chronic illness exists.
A generalized inflammatory response seen in chronic illness depletes the body's reserves to fight
against illness.
Which cells are the body's primary defense against parasite invasion? - (answers)Eosinophils are
the body's primary defense against parasites.
What Phagocytes bacteria? - (answers)Macrophages work by eating or phagocytosing bacteria.
What is the first response to a foreign pathogen? - (answers)Helper T cells
Which characteristic is the most important determinant of immunogenicity when considering the
antigen? - (answers)Immunogenicity is primarily based on the ability to recognize something
foreign.
心也是善良与爱的源泉。
,How are erythrocytes destroyed when mismatched blood is administered, causing an ABO
incompatibility? - (answers)The complement pathway is activated in response to blood
incompatibility.
What is the hypersensitivity reaction that causes atopic dermatitis? - (answers)An immediate
(type I) hypersensitivity reaction causes atopic dermatitis.
Which four infections are considered fungal infections? - (answers)Infection with a fungus is
called mycosis and includes dermatophytes (e.g., tineas, which refers to several skin mycoses,
including ringworm and athlete's foot) and yeasts, which include candida and aspergillus.
When is the earliest after sexual transmission of HIV that lab results can detect infection? -
(answers)Lab testing can detect HIV RNA 4 to 10 days after sexual transmission, whereas HIV
antibody testing may take 23 to 90 days to result in a positive test. Repeat testing may be needed
to rule out a false negative test due to testing too soon after exposure, especially if a high
likelihood of exposure is suspected.
What is a characteristic of exotoxins? - (answers)Exotoxins are released during bacterial growth.
Which dietary lifestyle choice has been associated with a decreased risk for developing colon
cancer? - (answers)The results of decreased fat consumption have been widely studied and have
demonstrated a decreased risk of developing colon cancer.
Which cancer is an individual who has worked with asbestos for over 40 years most likely to
develop? - (answers)Asbestos exposure results in an increased risk of lung and lung lining
cancer.
Which statement is true regarding ultraviolet (UV) light?
The degree of damage is not affected by the light's wavelength. - (answers)UV light causes basal
cell carcinoma and squamous cell carcinoma when the UVB rays hit DNA strands, causing
thymine base pairs that are side by side to pair together, becoming thymine dimers. These
thymine dimers lead to cell death or cancer.
心也是善良与爱的源泉。
, Which cancer does exercise have a convincing impact on reducing? - (answers)Exercise-induced
myokines cause apoptosis of colon cancer cells.
Low healthcare literacy is recognized as a major risk factor in blood pressure control and has
been shown to have adverse effects on health outcomes.
true or false - (answers)TRUE
By providing patient education at the appropriate literacy level, improved health outcomes may
result.
One of the goals of the National Action Plan to Improve Health Literacy is to incorporate
research and evidence-based plans of treatment from childhood through university-level
education in a manner consistent with an individual's literacy level.
True or false - (answers)True
Ensuring the individual can understand all elements of a treatment plan is crucial for
understanding and compliance.
What is a red flag for low healthcare literacy? - (answers)Low literacy often leads to perceived
noncompliance to medical instructions, including medication instructions. Ensuring the patient
fully understands all instructions is critical for understanding.
Amniocentesis is recommended for pregnant women with certain health histories.
Which health history would result in an amniocentesis recommendation? - (answers)Those who
have a family history of genetic disorders
Studies have identified several genes that play a role in the prevention of obesity.
What do these genes influence? - (answers)Regulation of appetite-Research has shown that
genetic mutations may cause alterations in the regulation of appetite.
Which concept is data reporting that sickle cell disease affects approximately 1 in 600 black
Americans an example of? - (answers)Prevalence tells us how often disease is seen in a
心也是善良与爱的源泉。
ADVANCED PRACTICE NURSE / ACTUAL EXAM TEST STUDY GUIDE /
(340+ Q&A) ACCURATE EXPERT VERIFIED FOR GUARANTEED PASS /
LATEST UPDATE
Which type of genetic disease affects males more frequently than females? - (answers)Sex-
Linked recessive. Since males only have one X and one Y, if the affected chromosome has the
illness, it will be expressed.
In which two conditions are chromosomal abnormalities the leading known cause? -
(answers)Intellectual disability and fetal miscarriage. Chromosome abnormalities are the leading
known cause of intellectual disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies? - (answers)Chorionic villus sampling
(CVS), amniocentesis, and preimplantation genetic testing (PGT) are examples of prenatal
diagnostic studies and are performed in vitro. CVS is a form of genetic testing that provides
genetic information found in utero and is usually performed between weeks 11 and 14 of
pregnancy. An amniocentesis is a form of genetic testing that evaluates amniotic fluid and is
usually performed during the second trimester, between weeks 15 and 20 of pregnancy. PGT is
performed on the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote having one chromosome
with a normal complement of genes and one chromosome with a missing gene? - (answers)Cri
du chat syndrome (translated as "cry of the cat") is caused by a DNA deletion. This term
describes the cry often heard from a baby affected by the syndrome. Cri du chat syndrome can
present as a microcephalic, low birth-weight baby with a piercing cry.
How can an X-linked recessive disease skip generations? - (answers)The disease can be
transmitted through female carriers.
心也是善良与爱的源泉。
,Since females have two copies of the X chromosome, the mother may provide an unaffected X to
a daughter or son. Furthermore, a daughter may not show signs of the disease because she has
the other X (the only X the father can give to a female) to cancel it out.
Which type of risk is referred to as the ratio of the disease rate among the entire population to the
disease rate in an unexposed population? - (answers)Relative risk is a ratio of probability, not an
actual occurrence of disease.
What are the empirical risks for most multifactorial diseases based on? - (answers)Many factors
from lifestyle to genetics affect multifactorial diseases. Observation and evaluation of each case
individually provides the most thorough and accurate assessment.
What refers to the silenced gene of a gene pair. - (answers)The imprinted gene is the silent gene
of a gene pair.
What is the primary reason that some older adults have impaired inflammation and wound
healing? - (answers)The underlying chronic illness exists.
A generalized inflammatory response seen in chronic illness depletes the body's reserves to fight
against illness.
Which cells are the body's primary defense against parasite invasion? - (answers)Eosinophils are
the body's primary defense against parasites.
What Phagocytes bacteria? - (answers)Macrophages work by eating or phagocytosing bacteria.
What is the first response to a foreign pathogen? - (answers)Helper T cells
Which characteristic is the most important determinant of immunogenicity when considering the
antigen? - (answers)Immunogenicity is primarily based on the ability to recognize something
foreign.
心也是善良与爱的源泉。
,How are erythrocytes destroyed when mismatched blood is administered, causing an ABO
incompatibility? - (answers)The complement pathway is activated in response to blood
incompatibility.
What is the hypersensitivity reaction that causes atopic dermatitis? - (answers)An immediate
(type I) hypersensitivity reaction causes atopic dermatitis.
Which four infections are considered fungal infections? - (answers)Infection with a fungus is
called mycosis and includes dermatophytes (e.g., tineas, which refers to several skin mycoses,
including ringworm and athlete's foot) and yeasts, which include candida and aspergillus.
When is the earliest after sexual transmission of HIV that lab results can detect infection? -
(answers)Lab testing can detect HIV RNA 4 to 10 days after sexual transmission, whereas HIV
antibody testing may take 23 to 90 days to result in a positive test. Repeat testing may be needed
to rule out a false negative test due to testing too soon after exposure, especially if a high
likelihood of exposure is suspected.
What is a characteristic of exotoxins? - (answers)Exotoxins are released during bacterial growth.
Which dietary lifestyle choice has been associated with a decreased risk for developing colon
cancer? - (answers)The results of decreased fat consumption have been widely studied and have
demonstrated a decreased risk of developing colon cancer.
Which cancer is an individual who has worked with asbestos for over 40 years most likely to
develop? - (answers)Asbestos exposure results in an increased risk of lung and lung lining
cancer.
Which statement is true regarding ultraviolet (UV) light?
The degree of damage is not affected by the light's wavelength. - (answers)UV light causes basal
cell carcinoma and squamous cell carcinoma when the UVB rays hit DNA strands, causing
thymine base pairs that are side by side to pair together, becoming thymine dimers. These
thymine dimers lead to cell death or cancer.
心也是善良与爱的源泉。
, Which cancer does exercise have a convincing impact on reducing? - (answers)Exercise-induced
myokines cause apoptosis of colon cancer cells.
Low healthcare literacy is recognized as a major risk factor in blood pressure control and has
been shown to have adverse effects on health outcomes.
true or false - (answers)TRUE
By providing patient education at the appropriate literacy level, improved health outcomes may
result.
One of the goals of the National Action Plan to Improve Health Literacy is to incorporate
research and evidence-based plans of treatment from childhood through university-level
education in a manner consistent with an individual's literacy level.
True or false - (answers)True
Ensuring the individual can understand all elements of a treatment plan is crucial for
understanding and compliance.
What is a red flag for low healthcare literacy? - (answers)Low literacy often leads to perceived
noncompliance to medical instructions, including medication instructions. Ensuring the patient
fully understands all instructions is critical for understanding.
Amniocentesis is recommended for pregnant women with certain health histories.
Which health history would result in an amniocentesis recommendation? - (answers)Those who
have a family history of genetic disorders
Studies have identified several genes that play a role in the prevention of obesity.
What do these genes influence? - (answers)Regulation of appetite-Research has shown that
genetic mutations may cause alterations in the regulation of appetite.
Which concept is data reporting that sickle cell disease affects approximately 1 in 600 black
Americans an example of? - (answers)Prevalence tells us how often disease is seen in a
心也是善良与爱的源泉。
