1|Page
AANPCB FNP EXAM 2 QUESTIONS & ANSWERS|
GRADE A| 100% CORRECT (VERIFIED SOLUTIONS)
(2026/ 2027 UPDATE)
1. A patient being treated for hepatitis C with oral ribavirin should be monitored
closely for which common side effect?
A. Weight gain
B. Depression
C. Hemolytic anemia
D. Hypothyroidism
CORRECT ANSWER: C. Hemolytic anemia
Rationale: Hemolytic anemia is the most common and significant side effect of
ribavirin therapy for hepatitis C. It results from accumulation of ribavirin in red
blood cells, leading to extravascular hemolysis. Regular monitoring of hemoglobin
and hematocrit is essential during treatment.
2. An early adolescent female is concerned because she has not yet begun to
menstruate. Physical examination reveals Sexual Maturity Rating IV with
,2|Page
average height and weight. What is the most appropriate response?
A. "We'll need to refer you to an endocrinologist for a complete workup."
B. "We'll need to do some tests to find out why you are not having periods."
C. "I'll give you some pills that will make your periods start."
D. "Your development is exactly as expected for your age; you'll probably begin to
have periods within a year."
CORRECT ANSWER: D. "Your development is exactly as expected for your
age; you'll probably begin to have periods within a year."
Rationale: Most females reach menarche by Sexual Maturity Rating IV, but some
may not menstruate until they reach Tanner stage V. With normal growth and
development, reassurance is appropriate. Evaluation for primary amenorrhea is
not indicated until age 15 or three years post-thelarche.
3. A patient is diagnosed with pelvic inflammatory disease (PID). The nurse
practitioner understands that major complications of PID include:
A. Polycystic ovaries and bleeding corpus luteum
B. Infertility and ectopic pregnancy
C. Diverticulitis and endometriosis
D. Pelvic organ prolapse
CORRECT ANSWER: B. Infertility and ectopic pregnancy
, 3|Page
Rationale: PID can cause scarring and damage to the fallopian tubes, leading to
tubal factor infertility and increased risk of ectopic pregnancy. The risk of these
complications increases with recurrent episodes of PID.
4. A patient has a positive tuberculin skin test with no symptoms and a normal
chest X-ray. What is the optimal treatment for latent tuberculosis?
A. Rifampin (Rifadin) for 5 months
B. Isoniazid (Nydrazid) for 9 months
C. Pyrazinamide for 6 months
D. Ethambutol for 6 months
CORRECT ANSWER: B. Isoniazid (Nydrazid) for 9 months
Rationale: The preferred regimen for latent TB infection is isoniazid 300 mg daily
for 9 months. Alternative regimens include rifampin for 4 months or
isoniazid/rifapentine weekly for 3 months. Pyrazinamide and ethambutol are used
in active TB treatment regimens.
5. A middle-aged female found a breast lump this morning. History includes: no
prior breast disease; G2P2 (first birth age 22); maternal aunt diagnosed with
breast cancer at age 72; LMP 2.5 weeks ago. Examination reveals a 2-cm round,
soft, mobile, tender lesion in the upper outer quadrant. Mammogram is
negative. What is the most appropriate next action?
AANPCB FNP EXAM 2 QUESTIONS & ANSWERS|
GRADE A| 100% CORRECT (VERIFIED SOLUTIONS)
(2026/ 2027 UPDATE)
1. A patient being treated for hepatitis C with oral ribavirin should be monitored
closely for which common side effect?
A. Weight gain
B. Depression
C. Hemolytic anemia
D. Hypothyroidism
CORRECT ANSWER: C. Hemolytic anemia
Rationale: Hemolytic anemia is the most common and significant side effect of
ribavirin therapy for hepatitis C. It results from accumulation of ribavirin in red
blood cells, leading to extravascular hemolysis. Regular monitoring of hemoglobin
and hematocrit is essential during treatment.
2. An early adolescent female is concerned because she has not yet begun to
menstruate. Physical examination reveals Sexual Maturity Rating IV with
,2|Page
average height and weight. What is the most appropriate response?
A. "We'll need to refer you to an endocrinologist for a complete workup."
B. "We'll need to do some tests to find out why you are not having periods."
C. "I'll give you some pills that will make your periods start."
D. "Your development is exactly as expected for your age; you'll probably begin to
have periods within a year."
CORRECT ANSWER: D. "Your development is exactly as expected for your
age; you'll probably begin to have periods within a year."
Rationale: Most females reach menarche by Sexual Maturity Rating IV, but some
may not menstruate until they reach Tanner stage V. With normal growth and
development, reassurance is appropriate. Evaluation for primary amenorrhea is
not indicated until age 15 or three years post-thelarche.
3. A patient is diagnosed with pelvic inflammatory disease (PID). The nurse
practitioner understands that major complications of PID include:
A. Polycystic ovaries and bleeding corpus luteum
B. Infertility and ectopic pregnancy
C. Diverticulitis and endometriosis
D. Pelvic organ prolapse
CORRECT ANSWER: B. Infertility and ectopic pregnancy
, 3|Page
Rationale: PID can cause scarring and damage to the fallopian tubes, leading to
tubal factor infertility and increased risk of ectopic pregnancy. The risk of these
complications increases with recurrent episodes of PID.
4. A patient has a positive tuberculin skin test with no symptoms and a normal
chest X-ray. What is the optimal treatment for latent tuberculosis?
A. Rifampin (Rifadin) for 5 months
B. Isoniazid (Nydrazid) for 9 months
C. Pyrazinamide for 6 months
D. Ethambutol for 6 months
CORRECT ANSWER: B. Isoniazid (Nydrazid) for 9 months
Rationale: The preferred regimen for latent TB infection is isoniazid 300 mg daily
for 9 months. Alternative regimens include rifampin for 4 months or
isoniazid/rifapentine weekly for 3 months. Pyrazinamide and ethambutol are used
in active TB treatment regimens.
5. A middle-aged female found a breast lump this morning. History includes: no
prior breast disease; G2P2 (first birth age 22); maternal aunt diagnosed with
breast cancer at age 72; LMP 2.5 weeks ago. Examination reveals a 2-cm round,
soft, mobile, tender lesion in the upper outer quadrant. Mammogram is
negative. What is the most appropriate next action?
