Chemotherapy study guide questions with answers |A+ GRADED EXAM | GUARANTEED PASS!!!!

Chemotherapy study guide questios with
verified solutions

Nadir - correct answer ✔the time when white blood cells and platelets are at
x x x x x x x x x x x x x


xthe lowest following chemo. Typically happens 7-14 days post chemo, with
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recovery by 21-28 days x x x




Tumor lysis syndrome - correct answer ✔Syndrome that occurs after chemo
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has been given. Occurs when the chemo causes rapid destruction of large
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amounts of tumor cells. Causes hyperuricemia which can lead to renal failure.
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xAlso causes hyperkalemia, hyperphosphatemia, and hypocalcemia
x x x x x




Vesicant - correct answer ✔types of drugs that can cause blisters and tissue
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necrosis.


Irritant - correct answer ✔drugs that cause burning in the IV
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Tumor burden - correct answer ✔the total amount of tumor in the patient's
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body


Neo-adjuvant treatment - correct answer ✔Chemotherapy given prior to
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primary treatment, such as surgery. Goal is to shrink the tumor prior to
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removal and/or to reduce the chance of micrometastatis
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Palliative treatment - correct answer ✔given to help relieve symptoms of
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cancer and improve quality of life
x x x x x

,Adjuvant treatment - correct answer ✔additional cancer treatment that is
x x x x x x x x x x


given after the primary curative treatment (surgery). Goal is to eradicate the
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residual disease, reduce recurrence rates, and reduce death rates.
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AUC dosing - correct answer ✔Area under the curve. Accounts for age,
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gender, weight, and renal function
x x x x




Routes of chemotherapy administration - correct answer ✔oral, intravenous,
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subcutaneous, intramuscular, intraperitoneal, intrathecal, intrapleural,
x x x x x


intravesicular, intraarterial, and HIPEC x x x




What drugs can be given intrathecally? - correct answer ✔Methotrexate and
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cytarabine


What are the two ways that intrathecal chemotherapy can be administered? -
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correct answer ✔Through an onmaya or through a lumbar puncture
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What is the rationale for the use of intrathecal chemotherapy? - correct
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answer ✔It goes directly into the central nervous system when there is CNS
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involvement with leukemia or lymphoma x x x x




What are common side effects/complications of intrathecal chemotherapy? -
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correct answer ✔Headache, changes in neuro status, new confusion
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Please define acute, delayed, and anticipatory nausea/vomiting and describe
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the treatment for each. - correct answer ✔Acute: occurs during the 1st 18-24
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, hours after chemo. Treatment includes zofran, fosfaprepitent, and
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dexamethasone.
Delayed: begins greater than 24 hours after chemo. Treatment includes
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fosfaprepitent, dexamethasone, and sometimes olanzapine. x x x x




Anticipatory: Begins prior to chemo. x x x x x




Treatment includes zofran and lorazepam. x x x x




Please discuss discharge instructions for nausea/vomiting management
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following chemotherapy. - correct answer ✔Eating cold foods and drinks can
x x x x x x x x x x x


be better to have rather than warm or hot foods which can make you more
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nauseous. Zofran can be taken 30 min prior to eating to help prevent nausea
x x x x x x x x x x x x x x


and vomiting.
x




Why is leucovorin administered with 5FU? - correct answer ✔To increase the
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cytotoxic effects of 5FU x x x




What test should be done prior to starting treatment with anthracyclines (ex.
x x x x x x x x x x x x


idarubicin, adriamycin)? - correct answer ✔ECHO to know the ejection
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fraction


How is cardiotoxicity monitored? And what signs and symptoms would you
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watch for? - correct answer ✔The physician gets a baseline EF prior to
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starting treatment and then they keeps track of lifetime cumulative doses. In
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acute toxicity you may see ECG changes and arrhythmias, in chronic it can
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manifest from symptomatic decline in EF to irreversible CHF.
x x x x x x x x




Please discuss the procedure for treating an extravasation, including where
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the orders are located. What specific treatment is used for an adriamycin
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extravasation. - correct answer ✔Stop the infusion, leave the iv in place and
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