1
Chemotherapy
Chemotherapy Biotherapy
Certification Exam Questions
with Correct Verified Answers
Latest Update (2024/2025)
Guaranteed Pass
1. Lesson 4 A cautionary tale about routes - ANS ✔intrathecal
x x x x x x x x x x
chemo- injects chemo directly into the subarachnoid space so it
x x x x x x x x x x
reaches the CNA x x
-leukemia and lymphoma spreading to CNS since most chemo does not
x x x x x x x x x x x
cross blood brain barrier x x x
2. intrathecal chemo - ANS ✔ONLY methotrexate and cytarabine
x x x x x x x x
can be given IT
x x x
-IT hydrocorisone given at same time to reduce inflammation
x x x x x x x x
3. vincristine - ANS ✔dilute in 20mL minibag and infuse over short
x x x x x x x x x x x
time- IVP not reommended
x x x
vinblastine -dilute in 25-50 ns x x x x
4. Lesson 5 Antitumor Antibiotics - ANS ✔-anthracyclines:
x x x x x x x
interfere with enzymes for DNA to replicate, work phases of the
x x x x x x x x x x x
cell cycle
x
lifetime dose limites because they are cardiotoxic
x x x x x x
-daunorubicin, doxorubicin, epirubicin, idarubicin
x x x
Chemotherapy x Biotherapy x Certification
, 2
Chemotherapy
nonanthracycline: actinomycin, mitomycin, bleomycin x x x
5. doxorubicin - ANS ✔vesicant x x x
extravasation possible- must eval cardiac funciton, ongoing cardiac
x x x x x x x x
monitoring, hypersensitivity risk x x
-nausea/ vomiting, mucositis, diarrhea, myelosupression, hepatic
x x x x x x
impairment, secondary cancer x x
-cardiac: SOB< skipped beats, weight gain
x x x x x
-myelosuppress: oral temp daily, report >100.5 x x x x x
GI: nausea vomiting diarrhea, inspect mucosa
x x x x x
neuro: numbness/ tingling, burning
x x x
GU: change in color of urine
x x x x x
6. dexrazoxane - ANS ✔cardiac protectant given before
x x x x x x
7. bleomycin - ANS ✔antitumor antibiotic - lifetime dose warning
x x x x x x x x
-can cause hypersensitivity, skin reaction
x x x x
-report SOB< skin issues, protect from sun
x x x x x x
8. Lesson 6 symptoms that can be dose limiting - ANS ✔chemo
x x x x x x x x x x x
induced nausea and vomiting
x x x
-lead to dehydration, dec functional status, increased costs and
x x x x x x x x x
withdrawal from treatment x x
-70% patient will experience.
x x x
Chemotherapy x Biotherapy x Certification
, 3
Chemotherapy
RISK Factors: younger, history of low alcohol consumption, female,
x x x x x x x x x
morning/ motion sickness x x
HEC: highly emetogenic - carmustine, cisplatin, cyclophosphamide,
x x x x x x x
daarbazine, mechlorethamine, streptozocin x x
9. CINV - ANS ✔chemo infuced nausea vomiting- vomiting center is
x x x x x x x x x x
central area responsible for CINV
x x x x
-patient are at risk for 2-3 days after last dose of cheom
x x x x x x x x x x x
10. Antiemetics - ANS ✔serotonin antagonists x x x x
-dolasetron, granisetron, ondansetron, palonosetron
x x x
neurokinin antagonists- aprepitant, fosaprepitant
x x x
steroids: dexamethasone x
11. Cutaneous Side effects of chemo - ANS ✔5FU and x x x x x x x x x
capecitabine has been noted to cause the worst skin resactions
x x x x x x x x x
-hand foot syndrome x x
-palmar plantar erythrodysesthesia - painful- flaking swelling blisters
x x x x x x x x
and sores x
avoid hot water, impacton feet and rubbing
x x x x x x
12. myelosuppression - ANS ✔suppression of bone marroe, x x x x x x x
red blood and platelets
x x x
NADIR: point at which blood cell counts are at the lowest after
x x x x x x x x x x x x
treatemtn. usually 7-1 days after cyce x x x x x
Chemotherapy x Biotherapy x Certification
Chemotherapy
Chemotherapy Biotherapy
Certification Exam Questions
with Correct Verified Answers
Latest Update (2024/2025)
Guaranteed Pass
1. Lesson 4 A cautionary tale about routes - ANS ✔intrathecal
x x x x x x x x x x
chemo- injects chemo directly into the subarachnoid space so it
x x x x x x x x x x
reaches the CNA x x
-leukemia and lymphoma spreading to CNS since most chemo does not
x x x x x x x x x x x
cross blood brain barrier x x x
2. intrathecal chemo - ANS ✔ONLY methotrexate and cytarabine
x x x x x x x x
can be given IT
x x x
-IT hydrocorisone given at same time to reduce inflammation
x x x x x x x x
3. vincristine - ANS ✔dilute in 20mL minibag and infuse over short
x x x x x x x x x x x
time- IVP not reommended
x x x
vinblastine -dilute in 25-50 ns x x x x
4. Lesson 5 Antitumor Antibiotics - ANS ✔-anthracyclines:
x x x x x x x
interfere with enzymes for DNA to replicate, work phases of the
x x x x x x x x x x x
cell cycle
x
lifetime dose limites because they are cardiotoxic
x x x x x x
-daunorubicin, doxorubicin, epirubicin, idarubicin
x x x
Chemotherapy x Biotherapy x Certification
, 2
Chemotherapy
nonanthracycline: actinomycin, mitomycin, bleomycin x x x
5. doxorubicin - ANS ✔vesicant x x x
extravasation possible- must eval cardiac funciton, ongoing cardiac
x x x x x x x x
monitoring, hypersensitivity risk x x
-nausea/ vomiting, mucositis, diarrhea, myelosupression, hepatic
x x x x x x
impairment, secondary cancer x x
-cardiac: SOB< skipped beats, weight gain
x x x x x
-myelosuppress: oral temp daily, report >100.5 x x x x x
GI: nausea vomiting diarrhea, inspect mucosa
x x x x x
neuro: numbness/ tingling, burning
x x x
GU: change in color of urine
x x x x x
6. dexrazoxane - ANS ✔cardiac protectant given before
x x x x x x
7. bleomycin - ANS ✔antitumor antibiotic - lifetime dose warning
x x x x x x x x
-can cause hypersensitivity, skin reaction
x x x x
-report SOB< skin issues, protect from sun
x x x x x x
8. Lesson 6 symptoms that can be dose limiting - ANS ✔chemo
x x x x x x x x x x x
induced nausea and vomiting
x x x
-lead to dehydration, dec functional status, increased costs and
x x x x x x x x x
withdrawal from treatment x x
-70% patient will experience.
x x x
Chemotherapy x Biotherapy x Certification
, 3
Chemotherapy
RISK Factors: younger, history of low alcohol consumption, female,
x x x x x x x x x
morning/ motion sickness x x
HEC: highly emetogenic - carmustine, cisplatin, cyclophosphamide,
x x x x x x x
daarbazine, mechlorethamine, streptozocin x x
9. CINV - ANS ✔chemo infuced nausea vomiting- vomiting center is
x x x x x x x x x x
central area responsible for CINV
x x x x
-patient are at risk for 2-3 days after last dose of cheom
x x x x x x x x x x x
10. Antiemetics - ANS ✔serotonin antagonists x x x x
-dolasetron, granisetron, ondansetron, palonosetron
x x x
neurokinin antagonists- aprepitant, fosaprepitant
x x x
steroids: dexamethasone x
11. Cutaneous Side effects of chemo - ANS ✔5FU and x x x x x x x x x
capecitabine has been noted to cause the worst skin resactions
x x x x x x x x x
-hand foot syndrome x x
-palmar plantar erythrodysesthesia - painful- flaking swelling blisters
x x x x x x x x
and sores x
avoid hot water, impacton feet and rubbing
x x x x x x
12. myelosuppression - ANS ✔suppression of bone marroe, x x x x x x x
red blood and platelets
x x x
NADIR: point at which blood cell counts are at the lowest after
x x x x x x x x x x x x
treatemtn. usually 7-1 days after cyce x x x x x
Chemotherapy x Biotherapy x Certification