PHARMACOLOGY | ALL QUESTIONS AND
CORRECT ANSWERS, Exams of
Pharmacology
Which Drugs can APRNS perscribe - Answer--DEA license will allow for prescribing schedules 2-5 there
can be restrictions as noted in collaborative agreement. maybe facility/state dependent.
Who determines and regulates prescriptive authority? - Answer--determines: APRNS can prescribe
without limitation and is state dependent. It is regulated by health professional board state board of
nursing or state board of medicine or pharmacy. federal government controls regulation but no control
over prescriptive authority.
How does limited prescriptive authority impact patients within the healthcare system? - Answer--
Creates numerous barriers to quality affordable and acessible patient care.
Key responsibilities to prescribing? - Answer--Do not prescribe to family/friends or yourself. document a
thorough history and physical examination. Include discussions with patient about risk factors and side
effects, medication monitoring or titration. if additional consults are made, know limitations, keep rx
pads in a safe place confirm allergies verify medication list dont let insurance dictate quality of RN
charting is key.
, what should be used to make prescribing decisions? - Answer--Cost, availability, current practice
guidelines, medication interactions with food side effects need for monitoring how drug is metabolized.
special populations. ask if prescriptions are cost prohibitive.
Pharmacokinetics - Answer--what the body does to the drug
Pharmacodynamics - Answer--what the drug does to the body
physilogic changes that can affect the pharmaconetics in older adults. - Answer--absorption: inc gastric
PH decreased absorptive surface area and dec splanchnic blood flow. dec GI motility delayed gastric
emptying distribution: inc body fat dec lean body mass dec total body water serum albumin cardiac
output. metabolism: dec hepatic blood flow mass and activity of hepatic enzymes. excretion: decreased
renal blood flow GFR tubular secretion and number of nephrons.
reducing adverse drug reaction in older adults? - Answer--Thorough drug history go low and slow with
initiating drug therapy monitor clinical responses and plasma levels use simple medication regimen,
monitor drug interaction review drug therapy dispose old medications promote adherence use beers
criteria.
Beers Criteria - Answer--A list of medications that are generally considered inappropriate when given to
elderly people
impacts of polypharmacy - Answer--using 5 or more medications daily leads to possible drug
interactions.
CYP450 inhibitors - Answer--CRACK AMIGOS
Chloramphenicol
Ritonavir (protease inhibitor)
Amiodarone
Ciprofloxacin