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NCLEX Study Guide 2025/2026 | Comprehensive Exam Prep & Practice Questions

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Ace the NCLEX-RN® or NCLEX-PN® with this comprehensive study guide for 2025/2026! Covering essential nursing topics such as pharmacology, patient safety, prioritization and delegation, disease management, lab values, and test-taking strategies, this guide provides detailed explanations, high-yield concepts, and practice test questions to reinforce key nursing knowledge. Designed for nursing students and graduates, this resource ensures a structured and effective review to help you pass the NCLEX with confidence on your first attempt. Strengthen your critical thinking skills and master the most tested NCLEX topics with ease!

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NCLEX Study Guide NCLEX Florida
National University

,A compilation of high-yield NCLEX topics presented in a simple and
easy-to-learn manner

, Table of Contents




Preparing for the NCLEX ……………………………………..……………………………………………………………………………… 3


General Nursing ………………………………………………………………………..……………………………………………………….. 5


Adult Health …………………………………………………………………………………………………………………………………….. 11


Diagnostic Tests ……………………………………………………………………………………………………………………………….. 33


Pediatrics ……………………………………………………………………….………………………………………………………………… 34


Maternity ………………………………………………………………………..……………………………………………………………….. 42


Critical Care ……………………………………………………………………………………………………………….…………………….. 47


Mental Health ……………………………………………………………………………………………………….…………….…………… 48


Leadership …………………………………………………………………………..……………………………………………...…………… 49


Pharmacology …………………………………………………………………………………………………..…………..………...………. 50


Test Taking Strategies …………………………………………………………………..………………………………………………….. 56




2

, Preparation for the NCLEX

• Start preparing as soon as you finish school. Starting your studying too early/while you are still in school (and
studying for exams) may cause burn out and lead to a more stressful NCLEX studying experience. On the other
hand, if you take off a large amount of time in between school and NCLEX studying, you’ll start to forget key
information you learned in nursing school that’s needed for the NCLEX.

• Order your study material during the last couple of weeks of school to ensure you have all your resources ready
for the upcoming weeks of studying (my favorite resources are listed below).

• Read over the National Council of State Boards of Nursing detailed test plan (there is an overview of what you’ll
be tested on and what percentage of the test is made up of what topics; e.g. 12% of the test will cover Safety and
Infection Prevention + Control).

• Create a study schedule and stick to it – my study calendar is found on the next page.

• Learn about the various alternate format questions and tips/tricks on how to answer them (e.g. Select All That
Apply [SATA], hot spot questions, fill in the blank questions, chart/audio/graphic questions, and drag-and-
drop/ordered questions).

• Find a study space that works for you. Personally, I studied at a library every single day and found it to be very
beneficial as I was able to focus without distractions and could also separate my study space and personal space.

• Remain positive and confident! If you find yourself over-worked, know that it’s okay to take a day off for self-
care… it’ll benefit you in the long run.


The following are resources I personally used while studying for the NCLEX and would highly recommend:
• Test-bank: uWorld
o This is the #1 resource I recommend
o The layout of uWorld is essentially identical to the NCLEX
o The test bank questions are slightly more difficult than the real NCLEX, which I believe will help prepare
you best for the test. It will also have you thinking more critically!
o You can go through the questions in a random order or system by system (which is what I chose to do)
and once you’re finished with the test bank, you can write a mock NCLEX with results that show you
the likelihood of you passing the NCLEX
• Book: Saunders Comprehensive Review for the NCLEX-RN
o This book includes everything you need to know for the NCLEX
o Not necessary to read every single page, but it’s a great resource to refer to when you are struggling
with a particular system or concept. If I got a uWorld question wrong, not only would I read the
rationale, but I would also read up on that particular information in my Saunders book

Study Material:
• Cue cards: I wrote out all my lab values on cue cards and reviewed all lab values every single day before my
study session began
• Binder split into sections: writing out uWorld rationales and keeping them in a binder for you to review weekly
is a great way to ensure that you don’t forget what you learned the previous week(s)
• Calculator, pens, highlighter, sticky notes/tabs, and earplugs
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