NAPLEX Review
CMEA requires purchasers of scheduled listed chemical products to present a photo ID. Which of the
following items is not an acceptable form of identification? - Answer-An employer-based security ID
A 76-year-old male with a past medical history of hypertension, myocardial infarction one year ago, and
normal left ventricular ejection fraction is receiving lisinopril and chlorthalidone daily. He now presents
to the emergency room with a 2-week history of palpitations, dizziness, leg swelling, and weight gain.
The ECG reveals atrial fibrillation with a ventricular rate of 140 bpm. - Answer-The patient should receive
dabigatran for at least 3 weeks before cardioversion and 4 weeks afterward.
Your class III prescription balance has a minimum weighable quantity of 80 mg. What is the sensitivity of
this balance? - Answer-4 mg
The most common presenting symptoms of acute leukemia are: - Answer-Fatigue and bruising
What is the treatment of choice for C. T.'s PCP? - Answer-TMP-SMX DS 2 tabs po q8h for 21 days, then 1
tab po daily
Which of the following is the only FDA-approved drug used to treat bulimia nervosa? - Answer-
Fluoxetine
,K. P. is a 34-year-old white male with a history of depression. He has had adequate trials of both
escitalopram and sertraline but complained of drowsiness and sexual side effects with both of these.
Which antidepressant would be a better choice to minimize these side effects? - Answer-Bupropion
When one is initiating warfarin therapy for acute venous thromboembolism, heparin or low-molecular-
weight heparin therapy should be given concomitantly for what length of time? - Answer-At least 5 days
How many grams per liter are needed to prepare 2N (normality) of H2SO4? - Answer-98 g
Which hormone imbalance and hormonal effect is incorrect? - Answer-Progestin excess →
hypermenorrhea, dysmenorrhea
Ampicillin is added to empiric meningitis regimens because of which pathogen? - Answer-L.
monocytogenes
Which oral triptan has the longest duration of action? - Answer-Frova
The primary advantage of cisatracurium over pancuronium and vecuronium is that - Answer-elimination
is not organ dependent.
Which of the following is the most appropriate venous thromboembolism prophylaxis in a patient with
an acute spinal cord injury? - Answer-Enoxaparin with or without intermittent pneumatic compression
devices
Which of the following is a treatment option for PN-induced hyperglycemia? - Answer-Addition of
regular human insulin to PN
Suppose a pharmacist weighs out 325 mg of a substance on her class A prescription balance. When she
subsequently checked this weight on a more sensitive analytical balance, she found it to be only 312 mg.
,What was the percentage error in the original weighing? - Answer-4%
Which one of the following immunosuppressants is associated with an increased risk of rhabdomyolysis
when adminstered with simvastatin ? - Answer-Cyclosporine
According to federal law, pharmacies have two options for filing prescription records. Which of the
following prescriptions would be filed separately from the others, in both systems? - Answer-Morphine
Sulfate
S. E. presents to the emergency department with a 2-day history of extreme nausea, vomiting, and
abdominal pain. Labs reveal elevations in amylase and lipase, and a diagnosis of pancreatitis is made. His
medications include nevirapine, tenofovir, didanosine, and amitriptyline. Which of his medications could
have caused his pancreatitis? - Answer-Didanosine
L. R. is a 52-year-old male with a history of chronic back pain resulting from a work-related injury 3 years
ago. His medications include pregabalin 75 mg bid, morphine SR 20 mg bid, morphine IR 5 mg tid prn
breakthrough pain (he reports using all three doses of morphine IR daily). His pain is not well controlled
and is affecting his personal relationships. His physician asks you to calculate an equianalgesic dose for a
different long-acting opioid. Which of the following doses of long-acting opioids is the most appropriate
for this patient? Do not use a cross-tolerance reduction in dosing. Use the following conversion table to
answer the question: - Answer-Oxycodone CR 20 mg twice daily
Your pharmacy discovers a significant loss of Lortab (acetaminophen and hydrocodone). The pharmacy
must notify the DEA - Answer-within 1 business day of the discovery.
Which of the following is an adverse effect of carvedilol? - Answer-Bradycardia
Which of the following medications is an oral option for the treatment of MRSA cellulitis? - Answer-
Zyvox 600 mg bid
, C. K. is on tenofovir/emtricitabine, darunavir, and ritonavir for her HIV. She has been diagnosed with
allergic rhinitis. You are asked to recommend a nasal corticosteroid. Which of the following would be a
good choice? - Answer-Beclomethasone
JD is a 56 y/o female who has been on estrogen-progestin therapy for 6 months without recurrence of
menopausal symptoms. She recently began taking another medication and has experienced a
recurrence of symptoms. Which one of the following medications could most likely be attributed to the
decreased pharmacologic effect of her estrogen therapy? - Answer-St. John's Wort
Which of the following sedative agents is least likely to cause respiratory depression? - Answer-
Dexmedetomidine
W. L. is a 56-year-old man who has been on a dose of prednisone 30 mg for the past 20 days. His doctor
is starting to titrate him off the medication and is wondering when would be an appropriate time to give
him his tetanus booster shot. You tell him that he should wait ________ month(s) before receiving any
vaccinations - Answer-W. L. can have his tetanus booster now without waiting.
Which of the following is the mechanism of action of rivaroxaban? - Answer-Inhibit factor Xa
The bioavailability and efficacy of which of the following antifungal agent is reduced by proton pump
inhibitors? - Answer-Itraconazole capsules
Which of the following β-blockers has ISA activity? - Answer-Sectral
You work for a chain of pharmacies that can access a real time, online database. How many times may
you transfer a prescription for a schedule III pain medication within the chain? - Answer-You may
transfer a prescription for a controlled substance up to the maximum refills permitted by law and by the
prescriber's authorization.
How many milliliters of a syrup containing 85% (w/v) sucrose should be mixed with 150 mL of a syrup
containing 60% (w/v) sucrose to make a syrup containing 80% (w/v) sucrose? - Answer-600 mL
CMEA requires purchasers of scheduled listed chemical products to present a photo ID. Which of the
following items is not an acceptable form of identification? - Answer-An employer-based security ID
A 76-year-old male with a past medical history of hypertension, myocardial infarction one year ago, and
normal left ventricular ejection fraction is receiving lisinopril and chlorthalidone daily. He now presents
to the emergency room with a 2-week history of palpitations, dizziness, leg swelling, and weight gain.
The ECG reveals atrial fibrillation with a ventricular rate of 140 bpm. - Answer-The patient should receive
dabigatran for at least 3 weeks before cardioversion and 4 weeks afterward.
Your class III prescription balance has a minimum weighable quantity of 80 mg. What is the sensitivity of
this balance? - Answer-4 mg
The most common presenting symptoms of acute leukemia are: - Answer-Fatigue and bruising
What is the treatment of choice for C. T.'s PCP? - Answer-TMP-SMX DS 2 tabs po q8h for 21 days, then 1
tab po daily
Which of the following is the only FDA-approved drug used to treat bulimia nervosa? - Answer-
Fluoxetine
,K. P. is a 34-year-old white male with a history of depression. He has had adequate trials of both
escitalopram and sertraline but complained of drowsiness and sexual side effects with both of these.
Which antidepressant would be a better choice to minimize these side effects? - Answer-Bupropion
When one is initiating warfarin therapy for acute venous thromboembolism, heparin or low-molecular-
weight heparin therapy should be given concomitantly for what length of time? - Answer-At least 5 days
How many grams per liter are needed to prepare 2N (normality) of H2SO4? - Answer-98 g
Which hormone imbalance and hormonal effect is incorrect? - Answer-Progestin excess →
hypermenorrhea, dysmenorrhea
Ampicillin is added to empiric meningitis regimens because of which pathogen? - Answer-L.
monocytogenes
Which oral triptan has the longest duration of action? - Answer-Frova
The primary advantage of cisatracurium over pancuronium and vecuronium is that - Answer-elimination
is not organ dependent.
Which of the following is the most appropriate venous thromboembolism prophylaxis in a patient with
an acute spinal cord injury? - Answer-Enoxaparin with or without intermittent pneumatic compression
devices
Which of the following is a treatment option for PN-induced hyperglycemia? - Answer-Addition of
regular human insulin to PN
Suppose a pharmacist weighs out 325 mg of a substance on her class A prescription balance. When she
subsequently checked this weight on a more sensitive analytical balance, she found it to be only 312 mg.
,What was the percentage error in the original weighing? - Answer-4%
Which one of the following immunosuppressants is associated with an increased risk of rhabdomyolysis
when adminstered with simvastatin ? - Answer-Cyclosporine
According to federal law, pharmacies have two options for filing prescription records. Which of the
following prescriptions would be filed separately from the others, in both systems? - Answer-Morphine
Sulfate
S. E. presents to the emergency department with a 2-day history of extreme nausea, vomiting, and
abdominal pain. Labs reveal elevations in amylase and lipase, and a diagnosis of pancreatitis is made. His
medications include nevirapine, tenofovir, didanosine, and amitriptyline. Which of his medications could
have caused his pancreatitis? - Answer-Didanosine
L. R. is a 52-year-old male with a history of chronic back pain resulting from a work-related injury 3 years
ago. His medications include pregabalin 75 mg bid, morphine SR 20 mg bid, morphine IR 5 mg tid prn
breakthrough pain (he reports using all three doses of morphine IR daily). His pain is not well controlled
and is affecting his personal relationships. His physician asks you to calculate an equianalgesic dose for a
different long-acting opioid. Which of the following doses of long-acting opioids is the most appropriate
for this patient? Do not use a cross-tolerance reduction in dosing. Use the following conversion table to
answer the question: - Answer-Oxycodone CR 20 mg twice daily
Your pharmacy discovers a significant loss of Lortab (acetaminophen and hydrocodone). The pharmacy
must notify the DEA - Answer-within 1 business day of the discovery.
Which of the following is an adverse effect of carvedilol? - Answer-Bradycardia
Which of the following medications is an oral option for the treatment of MRSA cellulitis? - Answer-
Zyvox 600 mg bid
, C. K. is on tenofovir/emtricitabine, darunavir, and ritonavir for her HIV. She has been diagnosed with
allergic rhinitis. You are asked to recommend a nasal corticosteroid. Which of the following would be a
good choice? - Answer-Beclomethasone
JD is a 56 y/o female who has been on estrogen-progestin therapy for 6 months without recurrence of
menopausal symptoms. She recently began taking another medication and has experienced a
recurrence of symptoms. Which one of the following medications could most likely be attributed to the
decreased pharmacologic effect of her estrogen therapy? - Answer-St. John's Wort
Which of the following sedative agents is least likely to cause respiratory depression? - Answer-
Dexmedetomidine
W. L. is a 56-year-old man who has been on a dose of prednisone 30 mg for the past 20 days. His doctor
is starting to titrate him off the medication and is wondering when would be an appropriate time to give
him his tetanus booster shot. You tell him that he should wait ________ month(s) before receiving any
vaccinations - Answer-W. L. can have his tetanus booster now without waiting.
Which of the following is the mechanism of action of rivaroxaban? - Answer-Inhibit factor Xa
The bioavailability and efficacy of which of the following antifungal agent is reduced by proton pump
inhibitors? - Answer-Itraconazole capsules
Which of the following β-blockers has ISA activity? - Answer-Sectral
You work for a chain of pharmacies that can access a real time, online database. How many times may
you transfer a prescription for a schedule III pain medication within the chain? - Answer-You may
transfer a prescription for a controlled substance up to the maximum refills permitted by law and by the
prescriber's authorization.
How many milliliters of a syrup containing 85% (w/v) sucrose should be mixed with 150 mL of a syrup
containing 60% (w/v) sucrose to make a syrup containing 80% (w/v) sucrose? - Answer-600 mL
