DHYG GEN PATH FINAL EXAM
Questions and Verified Answers
Lymphocytes and plasma cells
▪ B+T lymphocytes
▪ seen in chronic inflammation
▪ immune response
Platelets
blood clotting
eosinophils, basophils, mast cells
▪ Inflammation and immune response
▪ release histamine
Primary healing
▪ Surgical (sterile) wounds w/ clean borders
▪ heal 1st
Secondary healing
▪ Any non-sterile/infected wounds heal or deep and irregular borders
▪ heal 2nd
Determinants of healing
▪ site of wound
▪ mechanical factors
▪ size of wound
▪ presence/absence of infection ▪ circulatory status
▪ nutritional/metabolic factors
▪ age
,IgG
"Goo Goo Ga Ga" (baby)
--> Smallest
--> cross placenta
IgG --> Rh factor incompatibility
( Rh- mom, Rh+ dad, Rh+ fetus )
IgM
Mega size
iMMunization
--> acquired immunity
IgE
hypersensitivity I - severe rxns
--> 3 A's & a hay
--> Asthma
--> Anaphylaxis (allergEE)
--> Atopic dermatitis
--> Hay fever
emergencEE
IgD
B-lymphocytes
IgA
salivA
,mucosA
mamA's milk
Mucosal secretion
IgA
Lymphocytes (B & T) and plasma cells
seen in chronic inflammation and the immune response
* release histamines
* prominent in allergic reaction, hay fever, asthma (Type I hypersensitivity)
Type I Hypersensitivity
Asthma
Anaphylaxis (allergEE)
Atopic dermatitis
Hay fever
Type IV Hypersensitivity
cell-mediated,
DELAYED type of reaction.
12 -48 hours after.
EX: infectious disease, sarcoidosis, contacts dermatitis
Rh factor
Rh antigen → inherited
o Rh- women + Rh+ man = Rh+ baby
▪ the mother's antigen will cross the placenta and attack the baby's Rh+
, ▪ fetus can be fatal because of mother's anti-D antigen
▪ treatment → RhoGam: minimizes the production of antibodies created by the Rh- mother.
Rh- women + Rh+ man = ?
Rh+ baby
Rh factor treatment
RhoGAM
: minimizes the production of antibodies created by the Rh- mother.
Antibody
secreted by plasma cells; proteins that are specific to the antigen and stimulate an
immune response
Antigen
foreign substance that causes immune response to produce specific antibodies.
Benign tumors
MATURE CELLS
Slow expansion
Smooth external surface
capsule
Malignant tumors
IMMATURE CELLS
Fast expansion (invasive growth)
Irregular external surface
necrosis
Questions and Verified Answers
Lymphocytes and plasma cells
▪ B+T lymphocytes
▪ seen in chronic inflammation
▪ immune response
Platelets
blood clotting
eosinophils, basophils, mast cells
▪ Inflammation and immune response
▪ release histamine
Primary healing
▪ Surgical (sterile) wounds w/ clean borders
▪ heal 1st
Secondary healing
▪ Any non-sterile/infected wounds heal or deep and irregular borders
▪ heal 2nd
Determinants of healing
▪ site of wound
▪ mechanical factors
▪ size of wound
▪ presence/absence of infection ▪ circulatory status
▪ nutritional/metabolic factors
▪ age
,IgG
"Goo Goo Ga Ga" (baby)
--> Smallest
--> cross placenta
IgG --> Rh factor incompatibility
( Rh- mom, Rh+ dad, Rh+ fetus )
IgM
Mega size
iMMunization
--> acquired immunity
IgE
hypersensitivity I - severe rxns
--> 3 A's & a hay
--> Asthma
--> Anaphylaxis (allergEE)
--> Atopic dermatitis
--> Hay fever
emergencEE
IgD
B-lymphocytes
IgA
salivA
,mucosA
mamA's milk
Mucosal secretion
IgA
Lymphocytes (B & T) and plasma cells
seen in chronic inflammation and the immune response
* release histamines
* prominent in allergic reaction, hay fever, asthma (Type I hypersensitivity)
Type I Hypersensitivity
Asthma
Anaphylaxis (allergEE)
Atopic dermatitis
Hay fever
Type IV Hypersensitivity
cell-mediated,
DELAYED type of reaction.
12 -48 hours after.
EX: infectious disease, sarcoidosis, contacts dermatitis
Rh factor
Rh antigen → inherited
o Rh- women + Rh+ man = Rh+ baby
▪ the mother's antigen will cross the placenta and attack the baby's Rh+
, ▪ fetus can be fatal because of mother's anti-D antigen
▪ treatment → RhoGam: minimizes the production of antibodies created by the Rh- mother.
Rh- women + Rh+ man = ?
Rh+ baby
Rh factor treatment
RhoGAM
: minimizes the production of antibodies created by the Rh- mother.
Antibody
secreted by plasma cells; proteins that are specific to the antigen and stimulate an
immune response
Antigen
foreign substance that causes immune response to produce specific antibodies.
Benign tumors
MATURE CELLS
Slow expansion
Smooth external surface
capsule
Malignant tumors
IMMATURE CELLS
Fast expansion (invasive growth)
Irregular external surface
necrosis
