Pharmacology Exam 1 - Multiple Choice
1. The drug administration route demonstrating the slowest onset of action is
A. inhalation
B. transdermal
C. intramuscular
D. sublingual
E. intravenous -- Correct Answer --B
2. Symptoms of Parkinsonism would be increased by
A. excess levels of acetylcholine
B. treatment with some antipsychotic drugs
C. decreased levels of dopamine
D. drug administration after a high-protein meal
E. all of these -- Correct Answer --I had ABC highlighted I think this was a mistake
please edit
3. The study of drug absorption, distribution, metabolism, and excretion is known as
A. pharmacotherapeutics
B. pharmacodynamics
C. pharmacokinetics
D. pharmacy
E. posology -- Correct Answer --C
4. Barbiturate and benzodiazepine hypnotics both
, A. increase NREM stage 2 sleep
B. increase REM sleep
C. increase NREM stage 4 sleep
D. cause REM rebound
E. all of these statements are true -- Correct Answer --A. increase NREM stage 2
sleep
5. The main pharmacologic effect of the SSRIs is
A. increase levels of norepinephrine
B. increase levels of serotonin
C. decrease levels of norepinephrine
D. decrease levels of serotonin
E. decrease levels of dopamine -- Correct Answer --B. increase levels of serotonin
6. Apomorphine is classified as
A. MAO-B inhibitor
B. dopamine receptor agonist
C. COMT inhibitor
D. anticholinergic drug
E. DOPA decarboxylase inhibitor -- Correct Answer --B. dopamine receptor agonist
7. The antianxiety effect of buspirone (BuSpar) is associated with
A. stimulation of DA receptors
B. stimulation of serotonin receptors
C. blockage of serotonin receptors
, D. blockade of dopamine receptors
E. blockage of GABA receptors -- Correct Answer --C. blockage of serotonin
receptors
8. 10. The time a drug continues to produce its effect is its
A. ED50
B. maximal response
C. ceiling effect
D. onset of action
E. duration of action -- Correct Answer --E
9. 11. Flumazenil (Romazicon) is used to reverse the depressant effects of
A. clozapine
B. alprazolam (benzodiazepine)
C. haloperidol
D. chlorpromazine
E. thiothixene -- Correct Answer --alprazolam (benzodiazepine)
10. 12. What are the main areas at which benzodiazepines exert their effects?
A. limbic system
B. cerebral cortex
C. reticular formation
D. spinal cord
E. all of these -- Correct Answer --E. all of these
11. 13. First-pass metabolism refers to the metabolism of drugs in the
A. kidney
1. The drug administration route demonstrating the slowest onset of action is
A. inhalation
B. transdermal
C. intramuscular
D. sublingual
E. intravenous -- Correct Answer --B
2. Symptoms of Parkinsonism would be increased by
A. excess levels of acetylcholine
B. treatment with some antipsychotic drugs
C. decreased levels of dopamine
D. drug administration after a high-protein meal
E. all of these -- Correct Answer --I had ABC highlighted I think this was a mistake
please edit
3. The study of drug absorption, distribution, metabolism, and excretion is known as
A. pharmacotherapeutics
B. pharmacodynamics
C. pharmacokinetics
D. pharmacy
E. posology -- Correct Answer --C
4. Barbiturate and benzodiazepine hypnotics both
, A. increase NREM stage 2 sleep
B. increase REM sleep
C. increase NREM stage 4 sleep
D. cause REM rebound
E. all of these statements are true -- Correct Answer --A. increase NREM stage 2
sleep
5. The main pharmacologic effect of the SSRIs is
A. increase levels of norepinephrine
B. increase levels of serotonin
C. decrease levels of norepinephrine
D. decrease levels of serotonin
E. decrease levels of dopamine -- Correct Answer --B. increase levels of serotonin
6. Apomorphine is classified as
A. MAO-B inhibitor
B. dopamine receptor agonist
C. COMT inhibitor
D. anticholinergic drug
E. DOPA decarboxylase inhibitor -- Correct Answer --B. dopamine receptor agonist
7. The antianxiety effect of buspirone (BuSpar) is associated with
A. stimulation of DA receptors
B. stimulation of serotonin receptors
C. blockage of serotonin receptors
, D. blockade of dopamine receptors
E. blockage of GABA receptors -- Correct Answer --C. blockage of serotonin
receptors
8. 10. The time a drug continues to produce its effect is its
A. ED50
B. maximal response
C. ceiling effect
D. onset of action
E. duration of action -- Correct Answer --E
9. 11. Flumazenil (Romazicon) is used to reverse the depressant effects of
A. clozapine
B. alprazolam (benzodiazepine)
C. haloperidol
D. chlorpromazine
E. thiothixene -- Correct Answer --alprazolam (benzodiazepine)
10. 12. What are the main areas at which benzodiazepines exert their effects?
A. limbic system
B. cerebral cortex
C. reticular formation
D. spinal cord
E. all of these -- Correct Answer --E. all of these
11. 13. First-pass metabolism refers to the metabolism of drugs in the
A. kidney
