Walden 6630 Psychopharmacology
Midterm Study Guide 174 verified and
approved solutions.
Walden 6630 Psychopharmacology
Midterm Study Guide 174 verified and
approved solutions.
Serotonin regulates - ANSWER Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them from reuptake of serotonin to
increase levels in the synaptic cleft to bind with postsysnaptic 5HT2 receptors - ANSWER SSRIs
First line therapy for MDD due to milder side effect profiles - ANSWER SSRIs
Six Common SSRIs - ANSWER citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs - ANSWER 4-6 weeks
In addition to MDD, SSRIs also treat - ANSWER Chronic Anxiety, PTSD, OCD, and eating disorders
(bulimia)
Five Common side effects of SSRIs include - ANSWER Anxiety, insomnia, GI distress, sexual dysfunction
(ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old - ANSWER suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in combination with other serotonergic
drugs (SNRIs, TCAs, MAOIs, etc.) - ANSWER Serotonin Syndrome
,Walden 6630 Psychopharmacology
Midterm Study Guide 174 verified and
approved solutions.
Excess accumulation of serotonin resulting in overstimulation of the nervous system - ANSWER
Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - ANSWER Flushing, hyperthermia, agitation, muscle rigidity,
seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - ANSWER Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by - ANSWER blocking 5-HT2 receptors (serotonin
antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include - ANSWER
Irritability, headaches, and insomnia
Medicine specific side effect of citalopram - ANSWER Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with congenital heart defects - ANSWER
Paroxetine
All SSRIs but paroxetine (D) are pregnancy category - ANSWER C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes - ANSWER fluoxetine, fluvoxamine, and
paroxetine
Five common SNRIs include - ANSWER duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
, Walden 6630 Psychopharmacology
Midterm Study Guide 174 verified and
approved solutions.
This antidepressant class of medications works by binding to presynaptic SERT and NET to inhibit them
from reuptake of serotonin and norepinephrine to increase their levels in the synaptic cleft - ANSWER
SNRIs
In addition to MDD SNRIs treat - ANSWER Anxiety and neuropathic pain (peripheral neuropathy)
Medication specific indications of duloxetine: - ANSWER urinary incontinence and Fibromyalgia
Medication specific indications of venlafaxine: - ANSWER social anxiety, panic disorders, PTSD, OCD,
postmenopausal hot flashes
Six common side effects of SNRIs include: - ANSWER Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old: - ANSWER suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in combination with other serotonergic
drugs: - ANSWER Serotonin Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: - ANSWER venlafaxine
This SNRI is hepatotoxic: - ANSWER duloxetine
MAOIs increase the levels of: - ANSWER Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: - ANSWER alertness and focus
Dopamine regulates: - ANSWER cognitive function, motivation, and awakeness
Midterm Study Guide 174 verified and
approved solutions.
Walden 6630 Psychopharmacology
Midterm Study Guide 174 verified and
approved solutions.
Serotonin regulates - ANSWER Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them from reuptake of serotonin to
increase levels in the synaptic cleft to bind with postsysnaptic 5HT2 receptors - ANSWER SSRIs
First line therapy for MDD due to milder side effect profiles - ANSWER SSRIs
Six Common SSRIs - ANSWER citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs - ANSWER 4-6 weeks
In addition to MDD, SSRIs also treat - ANSWER Chronic Anxiety, PTSD, OCD, and eating disorders
(bulimia)
Five Common side effects of SSRIs include - ANSWER Anxiety, insomnia, GI distress, sexual dysfunction
(ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old - ANSWER suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in combination with other serotonergic
drugs (SNRIs, TCAs, MAOIs, etc.) - ANSWER Serotonin Syndrome
,Walden 6630 Psychopharmacology
Midterm Study Guide 174 verified and
approved solutions.
Excess accumulation of serotonin resulting in overstimulation of the nervous system - ANSWER
Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - ANSWER Flushing, hyperthermia, agitation, muscle rigidity,
seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - ANSWER Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by - ANSWER blocking 5-HT2 receptors (serotonin
antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include - ANSWER
Irritability, headaches, and insomnia
Medicine specific side effect of citalopram - ANSWER Prolonged QT interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with congenital heart defects - ANSWER
Paroxetine
All SSRIs but paroxetine (D) are pregnancy category - ANSWER C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes - ANSWER fluoxetine, fluvoxamine, and
paroxetine
Five common SNRIs include - ANSWER duloxetine, venlafaxine, desvenlafaxine, milnacipran,
levomilnacipran
, Walden 6630 Psychopharmacology
Midterm Study Guide 174 verified and
approved solutions.
This antidepressant class of medications works by binding to presynaptic SERT and NET to inhibit them
from reuptake of serotonin and norepinephrine to increase their levels in the synaptic cleft - ANSWER
SNRIs
In addition to MDD SNRIs treat - ANSWER Anxiety and neuropathic pain (peripheral neuropathy)
Medication specific indications of duloxetine: - ANSWER urinary incontinence and Fibromyalgia
Medication specific indications of venlafaxine: - ANSWER social anxiety, panic disorders, PTSD, OCD,
postmenopausal hot flashes
Six common side effects of SNRIs include: - ANSWER Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old: - ANSWER suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in combination with other serotonergic
drugs: - ANSWER Serotonin Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: - ANSWER venlafaxine
This SNRI is hepatotoxic: - ANSWER duloxetine
MAOIs increase the levels of: - ANSWER Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: - ANSWER alertness and focus
Dopamine regulates: - ANSWER cognitive function, motivation, and awakeness
