BCPS EXAM QUESTIONS AND ANSWERS
____ is the most appropriate answer because there are no drug-drug interactions or
contraindications / cautions in HIV - Answers :Bictegravir
n patients with persistent neutropenic fever despite anti-pseudomonal coverage, what
should be considered? - Answers :empiric antifungal therapy should be considered after
4 - 10 days
electrocautery - Answers :Which of the following therapies is most likely to result in a
resolution rate which approaches 100% in patients w/ external anogenital warts.?
preferred therapy for CMV retinitis? - Answers :Ganciclovir intravitreal injections plus
valganciclovir oral
bacterial vaginosis recommended treatment - Answers :clindamycin or metronidazole
(i.e. Clindamycin 300 mg orally twice daily for 7 days)
recommended treatment regimen for pelvic inflammatory disease - Answers
:Ceftriaxone 250 mg intramuscularly x 1 dose plus doxycycline 100 mg orally twice daily
for 14 days
vulvovaginal candidiasis teeatment - Answers :Clindamycin cream 2%, 5 g
intravaginally at bedtime for 7 days
MedWatch - Answers :preferred route for healthcare professionals and patients to report
suspected adverse events to the FDA
FDA Form 3500A - Answers :mechanism for reporting suspected adverse events, but is
reserved for use by user-facilities, importers, distributors, and manufacturers
-reporting errors related to vaccines - Answers :ISMP VERP and VAERS
viral rhinosinusitis sx duration - Answers :-peak at 3 days and may persist longer than
14 days but usually decreases in severity by 10 days
-watchful waiting is recommended to avoid overuse of antibiotics as episodes are often
self-limited
Malignant external otitis treatment - Answers :- predominantly caused by Pseudomonas
aeruginosa
-antipseudomonal antimicrobials are considered the mainstay of therapy.
Fidaxomicin - Answers :-associated with decreased recurrence of Clostridioides difficile
likely owing to its narrow spectrum and minimal effect on normal colonic flora
, duration of initial therapy for CDI? - Answers :10 days with oral vancomycin or
fidaxomicin
MRSA PCR - Answers :-well-recognized tool for antimicrobial de-escalation as part of
stewardship initiatives given the high negative predictive value
MRSA nasal culture - Answers :-used for surveillance and is not employed as a
stewardship tool
Procalcitonin - Answers :-useful in differentiating between viral and bacterial etiologies
-chronic kidney disease may cause an artificially high level leading to questionable
interpretation and potential continuation of inappropriate antimicrobials
Asymptomatic candiduria - Answers :-common among hospitalized patients with an
indwelling urinary catheter and treatment is nt is not warranted
elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (EVG/c/FTC/TAF) - Answers
:Elvitegravir is only available in single-tablet regimen form; either as EVG/c/FTC/TAF or
EVG/c/FTC/TDF. Therefore, it is not possible to stock the single agents and "break up"
the patient's regimen
Waterfall plot - Answers :-Waterfall plot is ideal to represent secondary objectives.
BRAF Mutation - Answers :BRAF mutation confers resistance to EGFR inhibitors; Anti-
EGFR therapies should be avoided in KRAS WT and BRAF mutant mCRC unless given
in combination with BRAF inhibitor
Palbociclib - Answers :-FDA approval for male breast cancer in combination with an
aromatase inhibitor or fulvestrant for men with hormone receptor-positive (HR+), human
epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast
cancer
Atezolizumab combined with nab-paclitaxel - Answers :-in breast CA is based on the
PD-L1 expression on tumor-infiltrating immune cells
Olaparib - Answers :-Breast cancer
-metastatic,
-HER2-negative -germline BRCA-mutated (gBRCAm)
Tvec indication - Answers :-second-line setting
- patients with skin involvement
-not metastatic
platinum-sensitive disease - Answers :=/> 6 months
____ is the most appropriate answer because there are no drug-drug interactions or
contraindications / cautions in HIV - Answers :Bictegravir
n patients with persistent neutropenic fever despite anti-pseudomonal coverage, what
should be considered? - Answers :empiric antifungal therapy should be considered after
4 - 10 days
electrocautery - Answers :Which of the following therapies is most likely to result in a
resolution rate which approaches 100% in patients w/ external anogenital warts.?
preferred therapy for CMV retinitis? - Answers :Ganciclovir intravitreal injections plus
valganciclovir oral
bacterial vaginosis recommended treatment - Answers :clindamycin or metronidazole
(i.e. Clindamycin 300 mg orally twice daily for 7 days)
recommended treatment regimen for pelvic inflammatory disease - Answers
:Ceftriaxone 250 mg intramuscularly x 1 dose plus doxycycline 100 mg orally twice daily
for 14 days
vulvovaginal candidiasis teeatment - Answers :Clindamycin cream 2%, 5 g
intravaginally at bedtime for 7 days
MedWatch - Answers :preferred route for healthcare professionals and patients to report
suspected adverse events to the FDA
FDA Form 3500A - Answers :mechanism for reporting suspected adverse events, but is
reserved for use by user-facilities, importers, distributors, and manufacturers
-reporting errors related to vaccines - Answers :ISMP VERP and VAERS
viral rhinosinusitis sx duration - Answers :-peak at 3 days and may persist longer than
14 days but usually decreases in severity by 10 days
-watchful waiting is recommended to avoid overuse of antibiotics as episodes are often
self-limited
Malignant external otitis treatment - Answers :- predominantly caused by Pseudomonas
aeruginosa
-antipseudomonal antimicrobials are considered the mainstay of therapy.
Fidaxomicin - Answers :-associated with decreased recurrence of Clostridioides difficile
likely owing to its narrow spectrum and minimal effect on normal colonic flora
, duration of initial therapy for CDI? - Answers :10 days with oral vancomycin or
fidaxomicin
MRSA PCR - Answers :-well-recognized tool for antimicrobial de-escalation as part of
stewardship initiatives given the high negative predictive value
MRSA nasal culture - Answers :-used for surveillance and is not employed as a
stewardship tool
Procalcitonin - Answers :-useful in differentiating between viral and bacterial etiologies
-chronic kidney disease may cause an artificially high level leading to questionable
interpretation and potential continuation of inappropriate antimicrobials
Asymptomatic candiduria - Answers :-common among hospitalized patients with an
indwelling urinary catheter and treatment is nt is not warranted
elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (EVG/c/FTC/TAF) - Answers
:Elvitegravir is only available in single-tablet regimen form; either as EVG/c/FTC/TAF or
EVG/c/FTC/TDF. Therefore, it is not possible to stock the single agents and "break up"
the patient's regimen
Waterfall plot - Answers :-Waterfall plot is ideal to represent secondary objectives.
BRAF Mutation - Answers :BRAF mutation confers resistance to EGFR inhibitors; Anti-
EGFR therapies should be avoided in KRAS WT and BRAF mutant mCRC unless given
in combination with BRAF inhibitor
Palbociclib - Answers :-FDA approval for male breast cancer in combination with an
aromatase inhibitor or fulvestrant for men with hormone receptor-positive (HR+), human
epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast
cancer
Atezolizumab combined with nab-paclitaxel - Answers :-in breast CA is based on the
PD-L1 expression on tumor-infiltrating immune cells
Olaparib - Answers :-Breast cancer
-metastatic,
-HER2-negative -germline BRCA-mutated (gBRCAm)
Tvec indication - Answers :-second-line setting
- patients with skin involvement
-not metastatic
platinum-sensitive disease - Answers :=/> 6 months
