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Quiz: A patient has been diagnosed with acute lymphocytic leukemia (ALL) and asks the healthcare professional to describe it. What description by the professional is most accurate? a. ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood b. In ALL, immature blasts cells replace normal myelocytic cells, megakaryocytes, and erythrocytes c. B cells fail to mature into plasma cells that synthesize immunoglobulins d. The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene identified as BCR-ABL Ans: a. ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood Quiz: Which of the following describes CML (Chronic Myelogenous Leukemia)? (Select all that apply.) a. Progresses rapidly b. Splenomegaly is a common finding in the accelerated phase c. Reciprocal translocation between chromosomes 9 and 22 (Philadelphia Chromosome) is present in 95% of cases d. Can lead to pancytopenia o © 2025 TestTrackers o or call [] o Resources & Updates: [Testtrackers - Stuvia US] o Your Success is Our Mission! o For online exams and tutor expert, please me in the number given. Ans: b. Splenomegaly is a common finding in the accelerated phase c. Reciprocal translocation between chromosomes 9 and 22 (Philadelphia Chromosome) is present in 95% of cases d. Can lead to pancytopenia Quiz: Folate and vitamin B12 deficiencies alter the synthesis of which of the following, which results in apoptotic destruction of maturing erythrocytes? a. Complement receptors on the cell surface b. Antigens on the cell surface c. DNA d. Mitochondria Ans: c. DNA Quiz: Hemophilia, a genetic bleeding disorder, is due to: a. Deficiencies of coagulation factor VIII, factor IX or factor XI b. Deficiency of tissue factor c. Deficiency in Vitamin K d. Deficiency of coagulation factor X Ans: a. Deficiencies of coagulation factor VIII, factor IX or factor XI Quiz: The characteristic sickling shape of the red blood cell in sickle cell anemia is due to: a. An autosomal recessive disease that results in the replacement of a o © 2025 TestTrackers o or call [] o Resources & Updates: [Testtrackers - Stuvia US] o Your Success is Our Mission! o For online exams and tutor expert, please me in the number given. proline amino acid with a threonine amino acid in hemoglobin β-chain b. An autosomal dominant disease that results in overproduction of RBCs c. Viral induced production of autoantibodies to hemoglobin resulting in RBC destruction

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Pathophysiology Practice Questions and Correct
Detailed Answers (Verified Answers) ||Already
Graded A+||Newest Version
Quiz: A patient has been diagnosed with acute lymphocytic leukemia (ALL) and asks the
healthcare professional to describe it. What description by the professional is most
accurate?

a. ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts
in the bone marrow or blood

b. In ALL, immature blasts cells replace normal myelocytic cells, megakaryocytes, and
erythrocytes

c. B cells fail to mature into plasma cells that synthesize immunoglobulins

d. The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene
identified as BCR-ABL

Ans: a. ALL is a progressive neoplasm defined by the presence of greater than 30%
lymphoblasts in the bone marrow or blood



Quiz: Which of the following describes CML (Chronic Myelogenous Leukemia)? (Select all
that apply.)

a. Progresses rapidly

b. Splenomegaly is a common finding in the accelerated phase

c. Reciprocal translocation between chromosomes 9 and 22 (Philadelphia Chromosome) is
present in 95% of cases

d. Can lead to pancytopenia




o
o
© 2025 TestTrackers
WhatsApp or call o Resources & Updates: [Testtrackers - Stuvia US]
[+254707240657] o Your Success is Our Mission!
o For online exams and tutor expert, please whatsapp me
in the number given.

, Ans: b. Splenomegaly is a common finding in the accelerated phase

c. Reciprocal translocation between chromosomes 9 and 22 (Philadelphia Chromosome) is
present in 95% of cases

d. Can lead to pancytopenia



Quiz: Folate and vitamin B12 deficiencies alter the synthesis of which of the

following, which results in apoptotic destruction of maturing erythrocytes?

a. Complement receptors on the cell surface

b. Antigens on the cell surface

c. DNA

d. Mitochondria

Ans: c. DNA



Quiz: Hemophilia, a genetic bleeding disorder, is due to:

a. Deficiencies of coagulation factor VIII, factor IX or factor XI

b. Deficiency of tissue factor

c. Deficiency in Vitamin K

d. Deficiency of coagulation factor X

Ans: a. Deficiencies of coagulation factor VIII, factor IX or factor XI



Quiz: The characteristic sickling shape of the red blood cell in sickle cell anemia is

due to:

a. An autosomal recessive disease that results in the replacement of a


o
o
© 2025 TestTrackers
WhatsApp or call o Resources & Updates: [Testtrackers - Stuvia US]
[+254707240657] o Your Success is Our Mission!
o For online exams and tutor expert, please whatsapp me
in the number given.

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