ONS/ONCC CHEMOTHERAPY
IMMUNOTHERAPY CERTIFICATION ACTUAL
EXAM 200+ QUESTIONS WITH DETAILED
VERIFIED ANSWERS 100% CORRECT
ALREADY GRADED A+ LATEST VERSION
"The 2 most important neurotransmitters involved in vomiting are: - CORRECT ANSWER=> 1.
Serotonin
2. Substance P"
"Describe the peripheral pathway of CINV - CORRECT ANSWER=> Primarily occurs in the GI tract
Associated with acute CINV
Neurotransmitter --> serotonin"
"Describe the central pathway of CINV - CORRECT ANSWER=> Primarily occurs in the brain
Associated with delayed CINV
Neurotransmitter --> Substance P"
"Common serotonin 5-HT3 antagonists used for CINV: - CORRECT ANSWER=> Dolasetron
Granisetron
Ondansetron
Palonosetron"
"Common neurokinin-1 antagonists used for CINV: - CORRECT ANSWER=> Aprepitant
Fosaprepitant"
"Common steroids used for CINV: - CORRECT ANSWER=> Dexamethasone"
"2 types of therapies that commonly have cutaneous reactions: - CORRECT ANSWER=> 1. EGFR
inhibitor therapies
2. Antimetabolites"
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,"Most-common cutaneous reaction seen with 5-FU and Capecitabine: - CORRECT ANSWER=>
Palmar-plantar erythrodysesthesia AKA hand-foot syndrome"
"Antimetabolites that commonly cause cutaneous reactions: - CORRECT ANSWER=> 5-FU
Capecitabine (Xeloda)"
"Define myelosuppression - CORRECT ANSWER=> Bone marrow activity is decreased, resulting in
fewer RBCs, WBCs and platelets
If severe: myeloablation"
"The most common dose-limiting toxicity of chemotherapy - CORRECT ANSWER=>
Myelosuppression"
"Define nadir, and when does it occur? - CORRECT ANSWER=> The point at which blood cell
counts are at their lowest following a treatment cycle.
Typically occurs 7-10 days following cycle"
"NCCN defines neutropenia as an ANC < _______/mm^3 - CORRECT ANSWER=> 500"
"Risk factors for developing neutropenia include: - CORRECT ANSWER=> > 65 years old
Hx of neutropenia with previous chemotherapy
Hx of chemotherapy or radiation treatment
Hematologic malignancy
Uncontrolled/advanced cancer
Lung cancer"
"Define neutropenic fever - CORRECT ANSWER=> Fever of 101 F or greater one time
OR
Fever of 100.4 F lasting one hour or longer"
"ANC calculation - CORRECT ANSWER=> (% polys + % bands) x (WBC)/100"
"Normal WBC count - CORRECT ANSWER=> 4,500-10,000"
"Normal neutrophil count - CORRECT ANSWER=> 54%-62% of WBC"
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, "An ANC of less that _____ is considered a risk for infection - CORRECT ANSWER=> 1,000"
"Define thrombocytopenia - CORRECT ANSWER=> Low platelet count"
"Symptoms of thrombocytopenia - CORRECT ANSWER=> Petechiae or easily bruising
Headaches
Hypotension and tachycardia
Prolonged bleeding (gums, menstruation)"
"Define anemia - CORRECT ANSWER=> Deficiency of RBC or hemoglobin in the blood"
"Symptoms of anemia - CORRECT ANSWER=> Dyspnea
Fatigue
Dizziness
Headaches"
"Acute diarrhea lasts: - CORRECT ANSWER=> 1-2 days and resolves on its own"
"Persistent diarrhea lasts: - CORRECT ANSWER=> 2-4 weeks"
"Chronic diarrhea lasts: - CORRECT ANSWER=> > 4 weeks"
"Common constipation-causing agents: - CORRECT ANSWER=> Vinca alkaloids (vincristine and
vinorelbine)
Thalidomide
Lenalidomide
Bortezomib"
"Define mucositis - CORRECT ANSWER=> Inflammation of the mucous membranes lining the
digestive tract from mouth to anus"
"Define stomatitis - CORRECT ANSWER=> Inflammatory conditions of the mouth specifically
AKA oral mucositis"
"Define xerostomia - CORRECT ANSWER=> Dryness of the mouth caused by damage to or
dysfunction of the salivary glands"
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IMMUNOTHERAPY CERTIFICATION ACTUAL
EXAM 200+ QUESTIONS WITH DETAILED
VERIFIED ANSWERS 100% CORRECT
ALREADY GRADED A+ LATEST VERSION
"The 2 most important neurotransmitters involved in vomiting are: - CORRECT ANSWER=> 1.
Serotonin
2. Substance P"
"Describe the peripheral pathway of CINV - CORRECT ANSWER=> Primarily occurs in the GI tract
Associated with acute CINV
Neurotransmitter --> serotonin"
"Describe the central pathway of CINV - CORRECT ANSWER=> Primarily occurs in the brain
Associated with delayed CINV
Neurotransmitter --> Substance P"
"Common serotonin 5-HT3 antagonists used for CINV: - CORRECT ANSWER=> Dolasetron
Granisetron
Ondansetron
Palonosetron"
"Common neurokinin-1 antagonists used for CINV: - CORRECT ANSWER=> Aprepitant
Fosaprepitant"
"Common steroids used for CINV: - CORRECT ANSWER=> Dexamethasone"
"2 types of therapies that commonly have cutaneous reactions: - CORRECT ANSWER=> 1. EGFR
inhibitor therapies
2. Antimetabolites"
1|Page
,"Most-common cutaneous reaction seen with 5-FU and Capecitabine: - CORRECT ANSWER=>
Palmar-plantar erythrodysesthesia AKA hand-foot syndrome"
"Antimetabolites that commonly cause cutaneous reactions: - CORRECT ANSWER=> 5-FU
Capecitabine (Xeloda)"
"Define myelosuppression - CORRECT ANSWER=> Bone marrow activity is decreased, resulting in
fewer RBCs, WBCs and platelets
If severe: myeloablation"
"The most common dose-limiting toxicity of chemotherapy - CORRECT ANSWER=>
Myelosuppression"
"Define nadir, and when does it occur? - CORRECT ANSWER=> The point at which blood cell
counts are at their lowest following a treatment cycle.
Typically occurs 7-10 days following cycle"
"NCCN defines neutropenia as an ANC < _______/mm^3 - CORRECT ANSWER=> 500"
"Risk factors for developing neutropenia include: - CORRECT ANSWER=> > 65 years old
Hx of neutropenia with previous chemotherapy
Hx of chemotherapy or radiation treatment
Hematologic malignancy
Uncontrolled/advanced cancer
Lung cancer"
"Define neutropenic fever - CORRECT ANSWER=> Fever of 101 F or greater one time
OR
Fever of 100.4 F lasting one hour or longer"
"ANC calculation - CORRECT ANSWER=> (% polys + % bands) x (WBC)/100"
"Normal WBC count - CORRECT ANSWER=> 4,500-10,000"
"Normal neutrophil count - CORRECT ANSWER=> 54%-62% of WBC"
2|Page
, "An ANC of less that _____ is considered a risk for infection - CORRECT ANSWER=> 1,000"
"Define thrombocytopenia - CORRECT ANSWER=> Low platelet count"
"Symptoms of thrombocytopenia - CORRECT ANSWER=> Petechiae or easily bruising
Headaches
Hypotension and tachycardia
Prolonged bleeding (gums, menstruation)"
"Define anemia - CORRECT ANSWER=> Deficiency of RBC or hemoglobin in the blood"
"Symptoms of anemia - CORRECT ANSWER=> Dyspnea
Fatigue
Dizziness
Headaches"
"Acute diarrhea lasts: - CORRECT ANSWER=> 1-2 days and resolves on its own"
"Persistent diarrhea lasts: - CORRECT ANSWER=> 2-4 weeks"
"Chronic diarrhea lasts: - CORRECT ANSWER=> > 4 weeks"
"Common constipation-causing agents: - CORRECT ANSWER=> Vinca alkaloids (vincristine and
vinorelbine)
Thalidomide
Lenalidomide
Bortezomib"
"Define mucositis - CORRECT ANSWER=> Inflammation of the mucous membranes lining the
digestive tract from mouth to anus"
"Define stomatitis - CORRECT ANSWER=> Inflammatory conditions of the mouth specifically
AKA oral mucositis"
"Define xerostomia - CORRECT ANSWER=> Dryness of the mouth caused by damage to or
dysfunction of the salivary glands"
3|Page
