MLS Immunology Exam (218 questions) with verified detailed solutions

MLS Immunology Exam (218 questions)
with verified detailed solutions

From the following, identify a specific component of the adaptive immune
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system that is formed in response to antigenic stimulation: - correct answer
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✔Immunoglobulin


Which two organs are considered the primary lymphoid organs in which
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immunocompetent cells originate and mature? - correct answer ✔Thymus n n n n n n n n n


and bone marrow
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What type of B cells are formed after antigen stimulation? - correct answer
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✔Plasma cells and memory B cells
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T cells travel from the bone marrow to the thymus for maturation. What is
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the correct order of the maturation sequence for T cells in the thymus? -
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correct answer ✔Maturation and selection occur in the cortex; migration to
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the medulla; release of mature T cells to secondary lymphoid organs
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Which CD marker appears during the first stage of T cell development and
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remains present as an identifying marker for T cells? - correct answer ✔CD
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two


Which markers are found on mature, peripheral helper T cells? - correct
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answer ✔CD two, three and four
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,Which T cell expresses the CD eight marker and acts specifically to kill
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tumors or virally infected cells? - correct answer ✔T cytotoxic
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How are cytotoxic T cells and natural killer cells similar? - correct answer
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✔Effective against virally infected cells n n n n




What is the name of the process by which phagocytic cells are attracted to a
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substance such as a bacterial peptide? - correct answer ✔Chemotaxis
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All of the following are immunologic functions of complement except: -
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correct answer ✔Induction of an antiviral state
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Which complement component is found in both the classic and alternative
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pathways? - correct answer ✔C three n n n n n




Which immunoglobulins help initiate the classic complement pathway? -
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correct answer ✔I g G and I g M
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How is complement activity destroyed in vitro? - correct answer ✔Heating
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serum at fifty six degrees Celsius for thirty minutes
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What is the purpose of C three a, C four a, and C five a, the split products
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of the complement cascade? - correct answer ✔To cause increased vascular
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permeability, contraction of smooth muscle, and release of histamine from
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basophils


Which region of the immunoglobulin molecule can bind antigen? - correct
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answer ✔F a b n n n

,Which region determines whether an immunoglobulin molecule can fix
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complement? - correct answer ✔C H n n n n n




Which immunoglobulin classes have a
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J chain? - correct answer ✔I g M and s I g A
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Which immunoglobulin appears first in the primary immune response? -
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correct answer ✔I g M
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Which immunoglobulin appears in highest titer in the secondary response? -
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correct answer ✔I g G
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Which immunoglobulin can cross the placenta? - correct answer ✔I g G
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Which immunoglobulin cross links mast cells to release histamine? - correct
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answer ✔I g E n n n




All of the following are functions of immunoglobulins except: - correct
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answer ✔Interacting with T cytotoxic cells to lyse viruses
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Which of the following cell surface molecules is
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classified as an MHC class two antigen? - correct answer ✔HLA DR
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Which MHC class of molecule is necessary for
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antigen recognition by CD four positive T cells? - correct answer ✔Class two
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, Which of the following are products of HLA class three genes? - correct
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answer ✔Complement proteins C two, C four, and Factor B
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What molecule on the surface of most T cells
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recognizes antigen? - correct answer ✔T c R, consisting of two chains, alpha
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and betan




The T cell antigen receptor is similar to immunoglobulin molecules in that it:
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- correct answer ✔Contains V and C regions on each of its chains
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Toll like receptors are found on which cells? - correct answer ✔Dendritic
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cells


Macrophages produce which of the following proteins during antigen
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processing? - correct answer ✔Interleukin one and interleukin six
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A superantigen, such as toxic shock syndrome
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toxin one, bypasses the normal antigen processing stage by binding to and
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cross linking: - correct answer ✔A portion of a T cell receptor and an MHC
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class two molecule
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T regulator cells, responsible for controlling autoimmune antibody
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production, express which of the following phenotypes? - correct answer
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✔CD three, four and twenty five
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