ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATION FINAL EXAM Questions with 100%
Correct Answers Latest Versions 2025 GRADED A+
What is cell mediated immunity dependent on? - Precise Answer
✔✔cytotoxic t-cells, helper t-cells and their cytokines
What are regulatory t-cells also known as? - Precise Answer
✔✔supressor t-cells
What do regulatory t-cells do? - Precise Answer ✔✔regulate the
immune response to prevent autoimmune reactions and limit
inflammatory responses
What are cytokines? - Precise Answer ✔✔cytokines are secreted
by lymphocytes with the intention of stimulating macrophages
and cytotoxic t lymphocytes to identify and kill pathogen
infected cells or tumor cells
What do proto-oncogenes do? - Precise Answer ✔✔regulate
normal cell growth and division.
,What are proto-oncogenes? - Precise Answer ✔✔they are a
large family of genes that code for proteins and enzymes that
turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it
can "turn on" and become what? - Precise Answer ✔✔oncogene
What are two examples of an oncogene? - Precise Answer
✔✔EGFR/Erb- B1 and Erb-B2/HER2
What is a very important tumor suppressor gene? - Precise
Answer ✔✔p53
What is the p53 gene also called? - Precise Answer ✔✔suicide
gene
What does neoadjuvant therapy refer to? - Precise Answer
✔✔treatment given as a first step to shrink a tumor before the
main treatment
What is adjuvant therapy? - Precise Answer ✔✔additional
cancer treatment given after the primary treatment to lower the
risk that cancer will occur
,How do alkylating agents function? - Precise Answer ✔✔by
causing a break in the DNA helix strand, causing interference
with DNA replication, which results in cell death
What are the three most common alkylating agent chemo's? -
Precise Answer ✔✔cytoxan, ifos, bendamustine
How are alkylating agents and platinum based chemo's
different? - Precise Answer ✔✔platinum based chemo's do not
have the molecule to to attach to and destroy DNA
What are the two most common platinum based chemo's? -
Precise Answer ✔✔cisplatin and carboplatin
What should you instruct patients to do when receiving
oxaliplatin? - Precise Answer ✔✔to avoid exposure to cold air
and consuming cold fluids for 3 to 4 days following treatment
What are the two most nephrotoxic drugs? - Precise Answer
✔✔streptozocin and semustine
, What are the most common side effects of antimetabolites? -
Precise Answer ✔✔myelosuppresion, GI toxicities,
photosensitivity, hand foot syndrome,
What kind of chemo therapy require life time doses? - Precise
Answer ✔✔antitumor antibiotics
What are examples of anthracyclines that? - Precise Answer
✔✔doxorubicin, daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - Precise
Answer ✔✔cardiotoxicity
What are classes of antitumor antibiotics? - Precise Answer
✔✔anthracyclines and non-anthracyclines
What are examples of non-anthracyclines? - Precise Answer
✔✔actinomycin d, mitomycin c, bleomycin
Why is there a lifetime dose for bleomycin? - Precise Answer
✔✔pulmonary fibrosis
CERTIFICATION FINAL EXAM Questions with 100%
Correct Answers Latest Versions 2025 GRADED A+
What is cell mediated immunity dependent on? - Precise Answer
✔✔cytotoxic t-cells, helper t-cells and their cytokines
What are regulatory t-cells also known as? - Precise Answer
✔✔supressor t-cells
What do regulatory t-cells do? - Precise Answer ✔✔regulate the
immune response to prevent autoimmune reactions and limit
inflammatory responses
What are cytokines? - Precise Answer ✔✔cytokines are secreted
by lymphocytes with the intention of stimulating macrophages
and cytotoxic t lymphocytes to identify and kill pathogen
infected cells or tumor cells
What do proto-oncogenes do? - Precise Answer ✔✔regulate
normal cell growth and division.
,What are proto-oncogenes? - Precise Answer ✔✔they are a
large family of genes that code for proteins and enzymes that
turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it
can "turn on" and become what? - Precise Answer ✔✔oncogene
What are two examples of an oncogene? - Precise Answer
✔✔EGFR/Erb- B1 and Erb-B2/HER2
What is a very important tumor suppressor gene? - Precise
Answer ✔✔p53
What is the p53 gene also called? - Precise Answer ✔✔suicide
gene
What does neoadjuvant therapy refer to? - Precise Answer
✔✔treatment given as a first step to shrink a tumor before the
main treatment
What is adjuvant therapy? - Precise Answer ✔✔additional
cancer treatment given after the primary treatment to lower the
risk that cancer will occur
,How do alkylating agents function? - Precise Answer ✔✔by
causing a break in the DNA helix strand, causing interference
with DNA replication, which results in cell death
What are the three most common alkylating agent chemo's? -
Precise Answer ✔✔cytoxan, ifos, bendamustine
How are alkylating agents and platinum based chemo's
different? - Precise Answer ✔✔platinum based chemo's do not
have the molecule to to attach to and destroy DNA
What are the two most common platinum based chemo's? -
Precise Answer ✔✔cisplatin and carboplatin
What should you instruct patients to do when receiving
oxaliplatin? - Precise Answer ✔✔to avoid exposure to cold air
and consuming cold fluids for 3 to 4 days following treatment
What are the two most nephrotoxic drugs? - Precise Answer
✔✔streptozocin and semustine
, What are the most common side effects of antimetabolites? -
Precise Answer ✔✔myelosuppresion, GI toxicities,
photosensitivity, hand foot syndrome,
What kind of chemo therapy require life time doses? - Precise
Answer ✔✔antitumor antibiotics
What are examples of anthracyclines that? - Precise Answer
✔✔doxorubicin, daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - Precise
Answer ✔✔cardiotoxicity
What are classes of antitumor antibiotics? - Precise Answer
✔✔anthracyclines and non-anthracyclines
What are examples of non-anthracyclines? - Precise Answer
✔✔actinomycin d, mitomycin c, bleomycin
Why is there a lifetime dose for bleomycin? - Precise Answer
✔✔pulmonary fibrosis
