QUESTIONS WITH SOLUTIONS GRADED A+
✔✔Name 4 typical antipsychotics - ✔✔1. haldol
2. fluphenazine
3. thioridazine
4. chlorpromazine
✔✔most dangerous side effect of typical anti psychotics - ✔✔neuroleptic malignant
syndrome
✔✔signs & symptoms of neuroleptic malignant syndrome - ✔✔rigid, fever, AMS
✔✔in neuroleptic malignant syndrome you must check - ✔✔CK level
✔✔how to treat neuroleptic malignant syndrome - ✔✔dantrolene
✔✔pros of atypical anti psychotics - ✔✔1. increased specificity for dopamine receptors
2. controls + and - sx by blocking D2 and 5HT receptors
3. less side effects
✔✔cons of atypical anti psychotics - ✔✔1. expensive
2. only available in oral
3. less potent than typical anti psychotics
✔✔name 6 examples of atypical antipsychotics - ✔✔1. risperdal
2. quetiapine
3. olanzapine
4. aripiprazole
5. ziprasadone
6. clozapine
✔✔top 2 side effects of atypical antipsychotics - ✔✔1. metabolic syndrome (diabates, wt
gain)
2. prolonged QT
✔✔1. most sensitive for D2 and 5HT receptors
2. best at controlling + and - symptoms - ✔✔clozapine
✔✔4 EPS symptoms (side effect) of anti psychotics - ✔✔1. akathesia
2. dystonia
3. dyskinesia
4. tardive dyskinesia
, ✔✔how to treat akathesia (restlessness) - ✔✔decrease dose of anti psychotic
✔✔involuntary spasms (torda colles, hand wringing, ocular gyro crisis) = - ✔✔dystonia
✔✔how to treat dystonia - ✔✔1. anti-cholinergics to decrease dystonia
2. continue anti psychotic
✔✔temporary parkinsonism is known as - ✔✔dyskinesia
✔✔how to treat parkinsonism - ✔✔1. anti-cholinergics like amantidine
2. continue anti psychotic
✔✔how to treat tardive dyskinesia - ✔✔1. stop offending agent
2. unfortunately tardive dyskinesia is irreversible
✔✔drug of choice for compliant, not complicated pt with schizophrenia - ✔✔oral atypical
✔✔drug of choice for noncompliant pt with schizophrenia - ✔✔typical antipsychotic in
the depot form (shot)
✔✔4 steps for pt hospitalized for schizophrenia but has never been on meds before -
✔✔1. start low dose oral atypical
2. increase dose of this atypical daily until reach max dose or reach a dose that pt
responds well to
3. discharge pt with whichever dose they responded well to
4. if all else fails- give typical or clozapine
✔✔an extremely agitated / psychotic pt shows up to the ED. which med should you
give? - ✔✔B52 (haldol, benadryl, lorazepam)
✔✔which anti psychotic should you give an elderly pt? - ✔✔atypicals b/c typicals have
anti-cholinergic effects`
✔✔4 rules of trying anti depressants - ✔✔1. try 1 medicine at least 6 weeks before
changing
2. try max dose of med before changing
3. continue med for at least 6 months before discontinuing
4. need 3 weeks of washout in between meds
✔✔name 4 typical anti depressants (SSRIs) - ✔✔1. fluoxetine
2. paroxetine
3. sertraline
4. (es)citalopram