Nurs 549 Drexel midterm Exam Questions
and answers 2025
Triglycerides .and .cholesterol .can .be: .- .CORRECT .ANSWER-Ingested .or
.synthesized .by .the .liver
Triglycerides .- .CORRECT .ANSWER-"Lipid"-FUEL .source, .ingested .or
.synthesized, .major .fuel, .fatty .acids .come .together .to .form .triglycerides.
Cholesterol .- .CORRECT .ANSWER-Structural .lipid, .BUILDING .BLOCK .compound,
.precursor .to .bile .salts .and .steroid .hormones
Chylomicron .- .CORRECT .ANSWER-Transports .INGESTED .triglycerides .to
.muscle .or .adipose, .water-soluble .transport
VLDL .- .CORRECT .ANSWER-Delivers .hepatic .(SYNTHESIZED .) .triglycerides .or
.cholesterol .to .muscle .or .tissue, .secreted .by .the .liver
IDL .- .CORRECT .ANSWER-intermediate .density .lipoprotein, .UNSTABLE, .more
.dense .than .VLDL .as .it .has .lost .some .triglycerides
HDL .- .CORRECT .ANSWER-high .density .lipoproteins .(healthy .good .type .of
.cholesterol), .synthesized .in .liver .and .gut, .attaches .to .vldl .and .chylomicrons
.like .a .GPS .to .take .them .to .target .location-has .cholesterol .and .lots .of .protein .in
.it, .HDL .picks .up .cholesterol .to .take .it .to .free .pool.
LDL .- .CORRECT .ANSWER-low .density .lipoprotein .(bad .cholesterol), .main .target
.of .lipid .therapy. .Most .dense .of .vldl .or .idl-has .the .least .amt .of .triglycerides.
LDL .- .CORRECT .ANSWER-Problem .child-free .radicals .in .oxidized .LDL, .get
.macrophage, .form .foam .cells .under .endothelium .of .arteries, .leading .to .the
.narrowed .lumen, .and .accumulate-result= .atherosclerotic .disease
bile .salts .- .CORRECT .ANSWER-made .by .cholesterol, .emulsify .dietary .fat,
.stored .in .gallbladder, .ejected .into .intestine .after .fatty .meal
Lipids .- .CORRECT .ANSWER-physiological .substance .that .is ."fat .soluble", .most
.are .good.
, Bile .Acid .Sequestrants .- .CORRECT .ANSWER-Cholestyramine .(Questran)
MOA .of .bile .acid .sequestrants .- .CORRECT .ANSWER-bond .with .bile .acids .to
.prevent .reabsorption .of .these .from .the .small .intestines, .thus .decreasing
.synthesis .of .cholesterol .and .reducing .LDLs
Bile .Acid .Sequestrants .MOA .- .CORRECT .ANSWER-prevent .reabsorption .of .bile
.acids .from .small .intestine; .bile .acids .are .necessary .for .absorption .of
.cholesterol, .excretes .bile .in .GI .tract .as .BM, .decreases .cholesterol, .this .forces
.liver .to .upregulate .LDL .receptors .to .get .cholesterol .in .pool .and .decreases .LDL
.in .plasma
Cardiovascular .atherosclerotic .disease .drugs .- .CORRECT .ANSWER-Most .drugs
.used .decrease .risk .of .CV .by .ultimately .shifting .normal .balance .to .require .liver
.to .upregulate .LDL .receptors .to .pull .LDL .from .plasma-targets .LDL .problem
.child .and .decreases .it .in .the .plasma
lipids .found .in .body .- .CORRECT .ANSWER-fatty .acids/triglycerides,
.phospholipids, .steroids, .cholesterol, .bile .salts, .eicosanoids .(prostaglandin
.precursor)
glucerophospholipids .- .CORRECT .ANSWER-embedded .in .cell .membrane,
.provide .hydrophobic .layer .b/t .H20 .and .cholesterol
Triglycerides .- .CORRECT .ANSWER-the .major .type .of .lipid .found .in .fatty .diet,
.undense, .very .heavy, .for .transport .TRG .are .packaged .with .apoproteins,
.phospholipids .and .cholesterol .to .create .water .soluble .compound .(VLDL)
TRG .ingestion .process: .- .CORRECT .ANSWER-1. .in .small .intestine-TRG
.emulsified .by .bile .salts
2. .broken .down .by .lipoprotein .lipase .into .monoglycerols .and .free .fatty .acids
3. .FFAs .packaged .into .micelles .and .absorbed .by .intest. .epithelium
4. .monoglycerols .and .FFAs .recombine .inside .as .triglycerides
TRG .INGESTED-transport .- .CORRECT .ANSWER-1. .TRG .packaged .into
.chylomicrons
2. .Destination .of .TRG- .adipose .(storage) .or .muscle .(fuel/energy)
LPL .- .CORRECT .ANSWER-lipoprotein .lipase
on .endothelial .surface, .breaks .TRG .apart .so .fatty .acids .are .removed .and .taken
.up .by .the .cell: .in .chylomicrons .& .VLDLs
Destination .of .cholesterol .- .CORRECT .ANSWER-cholesterol .pool .in .liver
Cholesterol .Ingestion .- .CORRECT .ANSWER-same .as .TRG .EXCEPT, .cholesterol
.destination .is .free .cholesterol .pool, .NOT .adipose .or .muscle.
HMGCoA .Reductase .pathway .- .CORRECT .ANSWER-Rate .limiting .step .in
.cholesterol .synthesis .Changes .HMGCoA .- .Mevalonate
and answers 2025
Triglycerides .and .cholesterol .can .be: .- .CORRECT .ANSWER-Ingested .or
.synthesized .by .the .liver
Triglycerides .- .CORRECT .ANSWER-"Lipid"-FUEL .source, .ingested .or
.synthesized, .major .fuel, .fatty .acids .come .together .to .form .triglycerides.
Cholesterol .- .CORRECT .ANSWER-Structural .lipid, .BUILDING .BLOCK .compound,
.precursor .to .bile .salts .and .steroid .hormones
Chylomicron .- .CORRECT .ANSWER-Transports .INGESTED .triglycerides .to
.muscle .or .adipose, .water-soluble .transport
VLDL .- .CORRECT .ANSWER-Delivers .hepatic .(SYNTHESIZED .) .triglycerides .or
.cholesterol .to .muscle .or .tissue, .secreted .by .the .liver
IDL .- .CORRECT .ANSWER-intermediate .density .lipoprotein, .UNSTABLE, .more
.dense .than .VLDL .as .it .has .lost .some .triglycerides
HDL .- .CORRECT .ANSWER-high .density .lipoproteins .(healthy .good .type .of
.cholesterol), .synthesized .in .liver .and .gut, .attaches .to .vldl .and .chylomicrons
.like .a .GPS .to .take .them .to .target .location-has .cholesterol .and .lots .of .protein .in
.it, .HDL .picks .up .cholesterol .to .take .it .to .free .pool.
LDL .- .CORRECT .ANSWER-low .density .lipoprotein .(bad .cholesterol), .main .target
.of .lipid .therapy. .Most .dense .of .vldl .or .idl-has .the .least .amt .of .triglycerides.
LDL .- .CORRECT .ANSWER-Problem .child-free .radicals .in .oxidized .LDL, .get
.macrophage, .form .foam .cells .under .endothelium .of .arteries, .leading .to .the
.narrowed .lumen, .and .accumulate-result= .atherosclerotic .disease
bile .salts .- .CORRECT .ANSWER-made .by .cholesterol, .emulsify .dietary .fat,
.stored .in .gallbladder, .ejected .into .intestine .after .fatty .meal
Lipids .- .CORRECT .ANSWER-physiological .substance .that .is ."fat .soluble", .most
.are .good.
, Bile .Acid .Sequestrants .- .CORRECT .ANSWER-Cholestyramine .(Questran)
MOA .of .bile .acid .sequestrants .- .CORRECT .ANSWER-bond .with .bile .acids .to
.prevent .reabsorption .of .these .from .the .small .intestines, .thus .decreasing
.synthesis .of .cholesterol .and .reducing .LDLs
Bile .Acid .Sequestrants .MOA .- .CORRECT .ANSWER-prevent .reabsorption .of .bile
.acids .from .small .intestine; .bile .acids .are .necessary .for .absorption .of
.cholesterol, .excretes .bile .in .GI .tract .as .BM, .decreases .cholesterol, .this .forces
.liver .to .upregulate .LDL .receptors .to .get .cholesterol .in .pool .and .decreases .LDL
.in .plasma
Cardiovascular .atherosclerotic .disease .drugs .- .CORRECT .ANSWER-Most .drugs
.used .decrease .risk .of .CV .by .ultimately .shifting .normal .balance .to .require .liver
.to .upregulate .LDL .receptors .to .pull .LDL .from .plasma-targets .LDL .problem
.child .and .decreases .it .in .the .plasma
lipids .found .in .body .- .CORRECT .ANSWER-fatty .acids/triglycerides,
.phospholipids, .steroids, .cholesterol, .bile .salts, .eicosanoids .(prostaglandin
.precursor)
glucerophospholipids .- .CORRECT .ANSWER-embedded .in .cell .membrane,
.provide .hydrophobic .layer .b/t .H20 .and .cholesterol
Triglycerides .- .CORRECT .ANSWER-the .major .type .of .lipid .found .in .fatty .diet,
.undense, .very .heavy, .for .transport .TRG .are .packaged .with .apoproteins,
.phospholipids .and .cholesterol .to .create .water .soluble .compound .(VLDL)
TRG .ingestion .process: .- .CORRECT .ANSWER-1. .in .small .intestine-TRG
.emulsified .by .bile .salts
2. .broken .down .by .lipoprotein .lipase .into .monoglycerols .and .free .fatty .acids
3. .FFAs .packaged .into .micelles .and .absorbed .by .intest. .epithelium
4. .monoglycerols .and .FFAs .recombine .inside .as .triglycerides
TRG .INGESTED-transport .- .CORRECT .ANSWER-1. .TRG .packaged .into
.chylomicrons
2. .Destination .of .TRG- .adipose .(storage) .or .muscle .(fuel/energy)
LPL .- .CORRECT .ANSWER-lipoprotein .lipase
on .endothelial .surface, .breaks .TRG .apart .so .fatty .acids .are .removed .and .taken
.up .by .the .cell: .in .chylomicrons .& .VLDLs
Destination .of .cholesterol .- .CORRECT .ANSWER-cholesterol .pool .in .liver
Cholesterol .Ingestion .- .CORRECT .ANSWER-same .as .TRG .EXCEPT, .cholesterol
.destination .is .free .cholesterol .pool, .NOT .adipose .or .muscle.
HMGCoA .Reductase .pathway .- .CORRECT .ANSWER-Rate .limiting .step .in
.cholesterol .synthesis .Changes .HMGCoA .- .Mevalonate
