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  • Universiteit Utrecht (UU)
  • Moleculaire Celbiologie
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Samenvatting H.1

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Moleculaire celbioliogie - Boek: essential cell biology - Samenvatting H.1

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Moleculaire celbiologie - H.1 – 06/09/2017

Het leven wordt gekenmerkt door cellen. Hooke en Leeuwenhoek zijn de grondleggers van de
celbiologie.

Kenmerken leven (cellen):
 Reproductie/groei/delen
 Metabolisme (stofwisseling)
 Reageren en aanpassen aan omgeving

DNA is het centrale Dogma van leven op aarde. Maar een virus heeft DNA/RNA maar leeft
niet. Dit komt omdat een virus zichzelf niet kan reproduceren en dus een gastheercel nodig
heeft.

Onderverdeling van het leven:
 Eukaryoten
 Prokaryoten
 Bacteriën
 Archea

Verschillen:
 Eukaryoten hebben celkernen en andere interne organellen (compartimentalizering)
 Eukaryote cellen zijn groter, meeste gevallen multicellulair en delen trager

Synthese: aanmaak van eiwitten in eucaryotische cel
Secretie: transport van eiwitten in een eucaryotische cel

Onderdelen cel:
 ER en Cytoplasma: maken eiwitten
 Golgiapparaat: sortering
 Mitochondrium: levering van energie
 Cytosol: hoge eiwitconcentratie, dikte van erwtensoep.
 Poriën kern: speciale filtering
 Vesciles; brengen nieuwe eiwitten van ER naar golgicomplex
 Cytoskelet: Stevigheid, beweging, vesiculair transport en celdeling
 Actine filamenten
 Microtubles
 Intermediate filamenten




Endocytose: import stoffen
in een cel

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  • moleculaire celbiologie
  • essential cell biology
  • mls
  • uu

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