3/13/2026, 5:17:26 AM 3/13/2026, 12th
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Chapter 01: General Principles of Pharmacology
Ford: Introductory Clinical Pharmacology 12th Edition
1. After teaching a group of students about the basics of pharmacology, the students will
be able to choose which aspect as the most critical to remember?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
Answer: C
Rationale: Pharmacology is the study of drugs and its action on living organisms. Thus, an
essential aspect of pharmacology is drug action. An understanding of the drug name, drug
class, and drug source is important, but the most critical aspect related to pharmacology is
how the drug acts in the body.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 1 Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process:
Teaching/Learning
Reference: p. 3, Introduction
2. A nurse suspects the client had an adverse reaction to a prescribed medication due to
an interaction with an unreported over-the-counter supplement. Which action by the nurse
will best assist in preventing future similar incidents?
A) File a report with MedWatch
B) File a report with the State Board of Nursing
C) Instruct the client to avoid combining medications in the future
D) Document the incident and report it to the health care provider
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
,3/13/2026, 5:17:26 AM 3/13/2026, 12th
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Answer: A
Rationale: Nurses play an important role in monitoring for adverse reactions. Therefore, it is
important to submit reports, even if there is uncertainty about the cause–effect relationship.
The FDA protects the identity of those who voluntarily report adverse reactions.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 9 Cognitive Level: Apply
Client Needs: Safe and Effective Care Environment: Safety and InfectionControl
Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 7, Box
1.1 MedWatch and Reporting Adverse Events
3. A nurse is assessing a client and notes the client has developed swelling of the eyelids
and lips after administration of a prescribed medication. What does the nurse interpret this
finding to specifically indicate?
A) Mild allergic reaction
B) Anaphylactic shock
C) Angioedema
D) Drug idiosyncrasy
Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by the collection of
fluid in the subcutaneous tissues, most commonly affecting the eyelids, lips, mouth, and
throat. Allergic reactions can be manifested by a wide range of signs and symptoms such as
itching, rashes, and hives. Anaphylactic shock is a serious allergic reaction that requires
immediate medical attention. Drug idiosyncrasydescribes anyunusual or abnormal reaction
to a drug, one that is different from the one normally expected.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 5 Cognitive Level: Apply
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
,3/13/2026, 5:17:26 AM 3/13/2026, 12th
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated Process: Clinical
Problem-solving Process (Nursing Process) Reference: p. 12, Allergic Drug Reactions
4. The nurse is preparing to teach a client about a new drug which is in the fourth phase
of development. Which activity will the nurse explain best illustrates this phase?
A) Health care providers report adverse effects to FDA.
B) Healthy volunteers are involved in the test.
C) In vitro tests are performed using human cells.
D) The drug is given to clients with the disease.
Answer: A
Rationale: The postmarketing surveillance phase of drug development encourages health
care professionals to report adverse effects of drugs to the FDA using MedWatch. Phase 1
of clinical testing involves 20 to 100 healthy volunteers. In vitro testing of the drug on human
or animal cells is done in the pre-FDA phase. In Phase 2 of clinical testing, the drug is given
to clients with the disease for which the drug is manufactured.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 4 Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance Integrated Process: Teaching/Learning
Reference: p. 7, Concept Mastery Alert
5. A nurse is assessing a pregnant client who admits to having a cocaine addiction. Which
condition of the baby after birth should the nurse explain and prepare the client for?
A) Diabetes
B) Hypertension
C) Addiction to drugs
D) CNS defects
Answer: C
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
, 3/13/2026, 5:17:26 AM 3/13/2026, 12th
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Rationale: The nurse informs the client that children born to mothers using addictive drugs
are often born with an addiction to the drug. Children born to mothers who are addicted to
cocaine are not known to be born with diabetes, CNS defects, or hypertension.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 6 Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance Integrated Process: Teaching/Learning
Reference: p. 11, Drug Use, Pregnancy, and Lactation
6. A client arrives at the health care clinic and reports taking several pills for a
headacheand severe cough without relief. Which adverse effect should the nurse be aware
may develop from this combination?
A) Gastrointestinal bleeding
B) Breathing difficulties
C) Liver damage
D) Anaphylaxis
Answer: C
Rationale: Consumers should be urged to carefully read the directions before taking over-
the-counter (OTC) drugs, as these drugs are not without risks. For example, acetaminophen,
commonly used for pain relief, is also found in many OTC products, such as cough and cold
remedies. When taken for both pain and in a cold remedy, this accumulative amount of the
drug can potentially harm a person's liver. Aspirin presents the potential adverse reaction
of gastrointestinal bleeding. An allergic reaction could result in breathing difficulties and
anaphylaxis.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 5 Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical
Problem-solving Process (Nursing Process) Reference: p. 5, Nonprescription Drugs
7. The nurse notes on assessment after administration of a drug that the clienthas
developed itching and a skin rash. The nurse interprets these findings as indicating which
possible reaction?
A) Toxicity
B) Allergic reaction
C) Angioedema
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Chapter 01: General Principles of Pharmacology
Ford: Introductory Clinical Pharmacology 12th Edition
1. After teaching a group of students about the basics of pharmacology, the students will
be able to choose which aspect as the most critical to remember?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
Answer: C
Rationale: Pharmacology is the study of drugs and its action on living organisms. Thus, an
essential aspect of pharmacology is drug action. An understanding of the drug name, drug
class, and drug source is important, but the most critical aspect related to pharmacology is
how the drug acts in the body.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 1 Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process:
Teaching/Learning
Reference: p. 3, Introduction
2. A nurse suspects the client had an adverse reaction to a prescribed medication due to
an interaction with an unreported over-the-counter supplement. Which action by the nurse
will best assist in preventing future similar incidents?
A) File a report with MedWatch
B) File a report with the State Board of Nursing
C) Instruct the client to avoid combining medications in the future
D) Document the incident and report it to the health care provider
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
,3/13/2026, 5:17:26 AM 3/13/2026, 12th
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Answer: A
Rationale: Nurses play an important role in monitoring for adverse reactions. Therefore, it is
important to submit reports, even if there is uncertainty about the cause–effect relationship.
The FDA protects the identity of those who voluntarily report adverse reactions.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 9 Cognitive Level: Apply
Client Needs: Safe and Effective Care Environment: Safety and InfectionControl
Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 7, Box
1.1 MedWatch and Reporting Adverse Events
3. A nurse is assessing a client and notes the client has developed swelling of the eyelids
and lips after administration of a prescribed medication. What does the nurse interpret this
finding to specifically indicate?
A) Mild allergic reaction
B) Anaphylactic shock
C) Angioedema
D) Drug idiosyncrasy
Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by the collection of
fluid in the subcutaneous tissues, most commonly affecting the eyelids, lips, mouth, and
throat. Allergic reactions can be manifested by a wide range of signs and symptoms such as
itching, rashes, and hives. Anaphylactic shock is a serious allergic reaction that requires
immediate medical attention. Drug idiosyncrasydescribes anyunusual or abnormal reaction
to a drug, one that is different from the one normally expected.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 5 Cognitive Level: Apply
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
,3/13/2026, 5:17:26 AM 3/13/2026, 12th
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated Process: Clinical
Problem-solving Process (Nursing Process) Reference: p. 12, Allergic Drug Reactions
4. The nurse is preparing to teach a client about a new drug which is in the fourth phase
of development. Which activity will the nurse explain best illustrates this phase?
A) Health care providers report adverse effects to FDA.
B) Healthy volunteers are involved in the test.
C) In vitro tests are performed using human cells.
D) The drug is given to clients with the disease.
Answer: A
Rationale: The postmarketing surveillance phase of drug development encourages health
care professionals to report adverse effects of drugs to the FDA using MedWatch. Phase 1
of clinical testing involves 20 to 100 healthy volunteers. In vitro testing of the drug on human
or animal cells is done in the pre-FDA phase. In Phase 2 of clinical testing, the drug is given
to clients with the disease for which the drug is manufactured.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 4 Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance Integrated Process: Teaching/Learning
Reference: p. 7, Concept Mastery Alert
5. A nurse is assessing a pregnant client who admits to having a cocaine addiction. Which
condition of the baby after birth should the nurse explain and prepare the client for?
A) Diabetes
B) Hypertension
C) Addiction to drugs
D) CNS defects
Answer: C
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
, 3/13/2026, 5:17:26 AM 3/13/2026, 12th
Introductory Clinical Pharmacology 5:17:18 AM by Susan M. Ford::2026
Edition 3/13/2026, 5:17:20 AM
Rationale: The nurse informs the client that children born to mothers using addictive drugs
are often born with an addiction to the drug. Children born to mothers who are addicted to
cocaine are not known to be born with diabetes, CNS defects, or hypertension.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 6 Cognitive Level: Apply
Client Needs: Health Promotion and Maintenance Integrated Process: Teaching/Learning
Reference: p. 11, Drug Use, Pregnancy, and Lactation
6. A client arrives at the health care clinic and reports taking several pills for a
headacheand severe cough without relief. Which adverse effect should the nurse be aware
may develop from this combination?
A) Gastrointestinal bleeding
B) Breathing difficulties
C) Liver damage
D) Anaphylaxis
Answer: C
Rationale: Consumers should be urged to carefully read the directions before taking over-
the-counter (OTC) drugs, as these drugs are not without risks. For example, acetaminophen,
commonly used for pain relief, is also found in many OTC products, such as cough and cold
remedies. When taken for both pain and in a cold remedy, this accumulative amount of the
drug can potentially harm a person's liver. Aspirin presents the potential adverse reaction
of gastrointestinal bleeding. An allergic reaction could result in breathing difficulties and
anaphylaxis.
Question Format: Multiple Choice Chapter: 1
Learning Objective: 5 Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical
Problem-solving Process (Nursing Process) Reference: p. 5, Nonprescription Drugs
7. The nurse notes on assessment after administration of a drug that the clienthas
developed itching and a skin rash. The nurse interprets these findings as indicating which
possible reaction?
A) Toxicity
B) Allergic reaction
C) Angioedema
3/27/2026,
3/13/2026, 5:37:04
5:17:24 PM
AM 3/27/2026,
3/13/2026, 5:37:03
5:17:23 PM
AM 3/27/2026,
3/13/2026, 5:36:58
5:17:21 PM
AM
