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VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
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MULTIPLE
CHOICE
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1. Which of thefollowing would bethe most likelycause of
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,A aniatrogenicdisease? ,A
a. An inheriteddisorder , A
b. Acombination ofspecificetiological factors ,A ,A ,A
c. Anunwanted effect of aprescribed drug ,A ,A ,A ,A , A
d. Prolonged exposureto toxicchemicals in theenvironment ,A ,A ,A ,A
ANS: C , A
2. Themanifestations of a disease arebest defined as the ,A ,A ,A ,A ,A ,A , A , A
a. subjective feelings ofdiscomfort duringa chronic illness. r̀ ,A ,A ,A ,A ,A
b. signs and symptoms of adisease. , A , A , A , A
c. factors that precipitate an acute episode of a chronicillness.
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d. earlyindicators oftheprodromal stageofinfection. ,A ,A ,A ,A ,A ,A
ANS: B , A
3. Thebest definition of the term prognosis is the
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a. precipitatingfactors causing an acute episode. r̀`! ,A r̀ ,A ,A
b. numberof remissions to be expected duringthe courseof a chronic illness. ,A ,A ,A `r ,A ,A ,A ,A `r
c. predictedoutcome or likelihood of recoveryfrom a specificdisease. ,A `r ,A ,A `r ,A ,A ,A
d. exacerbations occurringduring chronicillness. ,A ,A r̀`! ,A
ANS: C , A
4. Which ofthe followingis considered asystemic sign of disease?
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a. Swelling of theknee , A ,A
b. Fever
c. Pain in theneck , A , A
d. Red rash on theface , A ,A , A
ANS: B , A
5. Etiologyis defined as the studyof the ,A , A ,A , A ,A
a. causes of adisease. , A , A
b. course of adisease. , A , A
c. expected complications of a disease. r̀ ,A r̀ r̀
d. manifestations of adisease. , A , A
ANS: A , A
6. Atypeof cellular adaptation in which there is adecrease in cell size is referred to as
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a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D , A
7. A change in a tissue marked bycells that varyin size and shape and show
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, A increasedmitoticf igures would be called ,A `! ,A ,A ,A ,A ,A,A ,A,A ,A,A
, a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C , A
8. Adeficit of oxygen in the cells usuallydue to respiratoryor circulatoryproblems is called
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a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B , A
9. When a group of cells in the bodydies, the change is called
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a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D , A
10. Rigorous weightlifting/bodybuilding regimens mayresult in the skeletal
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musclecellsundergoing
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a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A , A
11. The term cancer refersto
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a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignantneoplasm. ,A
ANS: D , A
12. Towhich ofthe followingdoes theterm apoptosis refer?
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a. Increased rate ofmitosis bycertain cells ,A ,A ,A ,A , A
b. Ischemic damage tocells , A , A
c. Liquefaction of necrotictissue , A , A
d. Preprogrammed cellself-destruction ,A r̀`!
ANS: D , A
13. Whichof thefollowing statements is TRUE?
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a. AlterationofDNAdoes not changecell function. ,A ,A ,A `r,A ,A ,A
b. Damaged cells maybe abletorepairthemselves. ,A ,A ,A ,A ,A ,A
c. All types of cells die at the same rate.
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d. Mildischemia causes immediatecell death. ,A r̀ ,A ,A ,A
ANS: B , A
14. Caseation necrosis refers to an area where `r ,A ,A `r `r ,A
a. cell proteinshave been denatured. `r ,A ,A
, b. cellsareliquefied byenzymes. ,A ,A
c. dead cells form athick cheesysubstance.
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d. bacterial invasion hasoccurred. , A , A
ANS: C , A
15. Routineapplication ofsun block to skin would be an example of ,A ,A ,A `r ,A ,A ,A ,A ,A `r,A ,A
a. an iatrogenic cause ofcancer.
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b. a preventivemeasure.
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c. a precipitatingfactor.
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d. a predisposingcondition.
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ANS: B , A
16. Acircumstance that causes asudden acute episode ofa chronic disease to occur is termed
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a. latentstage.
b. predisposingfactor. r̀`!
c. incidence.
d. precipitating factor. `r
ANS: D , A
17. Theterm homeostasis refers to ,A ,A `r
a. thecausative factors in a particulardisease. ,A ,A ,A ,A ,A
b. maintenanceof a stableinternal environment. r̀`! ,A r̀ ,A ,A
c. a condition that triggers an acute episode.
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d. a collection ofsigns and symptoms.
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ANS: B , A
18. Which term is used to describe a new and secondaryor additional problem that arises
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, A aftertheoriginal disease has been established?
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a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D , A
19. Pathophysiologyinvolves thestudyof ,A ,A
a. the structureof the human body.
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b. thefunctions ofvarious organs in the body. ,A ,A ,A ,A ,A ,A
c. functionalorstructural changes resultingfrom disease processes.
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d. variouscellstructures andrelatedfunctions. ,A ,A ,A ,A ,A
ANS: C , A
20. Which ofthefollowing is the best definition ofepidemiology?
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a. Thescienceof tracking theoccurrence and distribution ofdiseases ,A ,A r̀ ,A ,A ,A ,A ,A
b. Therelative number ofdeaths resulting from a particulardisease ,A ,A ,A ,A ,A ,A ,A ,A
c. Identificationof a specific diseasethrough evaluation ofsigns ands ymptoms ,A ,A `r ,A ,A ,A ,A ,A
d. Theglobal search foremerging diseases ,A , A ,A `r,A
ANS: A , A