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,NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
Terms in this set (54)
What is selective toxicity? Targeting microbial structures absent in human cells (cell wall, enzymes,
ribosomes, DNA/RNA).
What structures do antimicrobials target for selective Cell wall, microbial enzymes, ribosomes, DNA/RNA synthesis, viral
toxicity? replication.
What are the main mechanisms of antimicrobial Cell wall destruction, enzyme inhibition, protein synthesis inhibition,
action? DNA/RNA disruption.
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
,NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
What does bactericidal mean? Kills organisms; required for immunocompromised patients.
What does bacteriostatic mean? Inhibits growth; relies on intact host immunity.
What are the non-negotiables when choosing an Identify organism, determine sensitivity (MIC), assess host factors, obtain
antimicrobial? cultures first, drug must meet/exceed MIC.
What is the benefit of narrow-spectrum antibiotics? Lower resistance and lower superinfection risk.
What is the risk of broad-spectrum antibiotics? Increased resistance and increased superinfection risk (C. difficile).
Who is at high risk for antimicrobial toxicity? Infants, older adults, pregnant/lactating clients, and those with antibiotic
allergies.
When is antimicrobial prophylaxis appropriate? Surgery, prosthetic valves, recurrent UTIs.
What indicates antimicrobial effectiveness? Clinical improvement.
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
, NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
What does persistent infection despite antibiotics Resistance or incorrect drug choice.
suggest?
What is the RN priority before starting antibiotics? Obtain cultures first.
Why must clients complete the full antibiotic course? To prevent resistance.
What is the function of the bacterial cell wall? Maintains osmotic stability and shape.
Why do cell wall antibiotics work? Humans lack cell walls, allowing selective toxicity.
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf
NURS 318- Mod 11_ Antimicrobial Principles & Antibiotics Affecting the Bacterial Cell Wall.pdf