Oncology Nursing
Biotherapy
Study Guide.pdf
Certification _Chemotherapy
Oncology Nursing
Biotherapy
Study Guide.pdf
Certification _ Oncology Nursing Study Guide.pdf
Chemotherapy Biotherapy Certification |
Oncology Nursing Study Guide
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Chemotherapy Biotherapy Certification _Chemotherapy
Oncology Nursing
Biotherapy
Study Guide.pdf
Certification _Chemotherapy
Oncology Nursing
Biotherapy
Study Guide.pdf
Certification _ Oncology Nursing Study Guide.pdf
,Chemotherapy Biotherapy Certification.pdf Chemotherapy Biotherapy Certification.pdf Chemotherapy Biotherapy Certification.pdf
Terms in this set (95)
Resources nccn.org
cancer.org
LESSON 1: Cell cycle g1- increase in size
s- dna replicated
g2- cell enlarge and ready to divide
m phase- 2 hours
mitosis 4 stages, prophase, metaphase, anaphase, telophase
-chemo targets certain points in the process
apoptosis programmed cell death
hematopoiesis formation of blood cells & how cells differentiate
-myeloid: pre cells mature into RBCs, platelets and WBCs
-lymphoid: pre cells- mature into WBCS
Principles of Biotherapy: p51-95 immunology -defense against foreign organisms, homeostasis (destroy aged cells),
surveillance
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immune responses innate: primary line of defense, non specific, no memory
adaptive: secondary line of defence with specific memry
cytokines -effect growth and differentiation of WBC
-interferons, tumor necrosis factors, growth factos and interleukins
-small protein molecules released by cells throughout body providing
comunication between cells of the immune system
-regular antiboddy production and function of b cells
vaccines for cancer prevention -hep B prevents hepatitis and hepatocellular carcinoma
-hpv vaccine
filgrastim aka neupogen SC or IV to derease infection in patients with neutropenic fever
associated with myelosuppressive anticancer treatments for nonmyeloid
malignancies
tbo-filgramstim/ pegfilgrastim reduce duration of neutroenia in patients with non myeloid malignancies
palifermin IV to dec incidence of oral mucositis in patients with hem malignanies
before BMT
sargramostim aka leukine - patients with AML following chemo to shorten neutrophil
recovery and reduce incidence of infection
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IFN gamma reduce frequency and severity o infections related to granulomatous
disease
aldeleukin treat renal cell carcinoma and metastatic melanoma
oprevelkin prevent severe thrombocytopenia and refuce need for platelet
transfusions in patients with nonmyeloid malig
plerixafor with filgrastim to mobilize hematopoeitc stem cells for collection from
peripheral blood of patients
sipuleucel castrate resistant prostate cancer
rituximab rituxan- treatment of relapsed or refractory low grade follicular b cell
NHL_ first line traetment in combo with chemo in patients with response
-can treat severe rheumatoid arthritis
-can have severe reactions (hypotension, urticaria, angiodema, hypoxia,
rigors, dyspnea, chills, fever, nausea, rash, renal tox)
-premed with tylenol and benadryl
-slow infusion to resolve some side effects, side effects reduce with each
infusion
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